The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
LEAFY COTYLEDON2 encodes a B3 domain transcription factor that induces embryo development
Open accessAbstract
The Arabidopsis LEAFY COTYLEDON 2 ( LEC2 ) gene is a central embryonic regulator that serves critical roles both early and late during embryo development. LEC2 is required for the maintenance of suspensor morphology, specification of cotyledon identity, progression through the maturation phase, and suppression of premature germination. We cloned the LEC2 gene on the basis of its chromosomal position and showed that the predicted polypeptide contains a B3 domain, a DNA-binding motif unique to plants that is characteristic of several transcription factors. We showed that LEC2 RNA accumulates primarily during seed development, consistent with our finding that LEC2 shares greatest similarity with the B3 domain transcription factors that act primarily in developing seeds, VIVIPAROUS1/ABA INSENSITIVE3 and FUSCA3. Ectopic, postembryonic expression of LEC2 in transgenic plants induces the formation of somatic embryos and other organ-like structures and often confers embryonic characteristics to seedlings. Together, these results suggest that LEC2 is a transcriptional regulator that establishes a cellular environment sufficient to initiate embryo development.
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Cites
A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of Arabidopsis
Long, J. A., Moan, E. I., Medford, J. I., & Barton, M. K. (1996) · Nature · doi:10.1038/379066a0 · Cited by 1,537
Di Laurenzio, L., Wysocka-Diller, J., Malamy, J. E., Pysh, L., Helariutta, Y., Freshour, G., Hahn, M. G., Feldmann, K. A., & Benfey, P. N. (1996) · Cell · doi:10.1016/s0092-8674(00)80115-4 · Cited by 1,124
Cited by
Molecular networks regulating Arabidopsis seed maturation, after‐ripening, dormancy and germination
Holdsworth, M. J., Bentsink, L., & Soppe, W. J. J. (2008) · New Phytologist · doi:10.1111/j.1469-8137.2008.02437.x · Cited by 964
Morphogenic Regulators Baby boom and Wuschel Improve Monocot Transformation
Lowe, K., Wu, E., Wang, N., Hoerster, G., Hastings, C., Cho, M.-J., Scelonge, C., Lenderts, B., Chamberlin, M., Cushatt, J., et al. (2016) · The Plant Cell · doi:10.1105/tpc.16.00124 · Cited by 881
“…in response to overexpression of plant morphogenic genes such as LEAFY COTYLEDON1 (Lotan et al., 1998), Lec1 (Lowe et al., 2002), LEAFY COTYLEDON2 (Stone et al., 2001), WUSCHEL (WUS; Zuo et al., 2002), and BABY BOOM (BBM; Boutilier et al., 2002) as well as enhanced regeneration (Srinivasan et…”
BackgroundHorstman, A., Li, M., Heidmann, I., Weemen, M., Chen, B., Muino, J. M., Angenent, G. C., & Boutilier, K. (2017) · Plant Physiology · doi:10.1104/pp.17.00232 · Cited by 361
Bies-Ethève, N., Gaubier-Comella, P., Debures, A., Lasserre, E., Jobet, E., Raynal, M., Cooke, R., & Delseny, M. (2008) · Plant Molecular Biology · doi:10.1007/s11103-008-9304-x · Cited by 308
The gene TaWOX5 overcomes genotype dependency in wheat genetic transformation
Wang, K., Shi, L., Liang, X., Zhao, P., Wang, W., Liu, J., Chang, Y., Hiei, Y., Yanagihara, C., Du, L., et al. (2022) · Nature Plants · doi:10.1038/s41477-021-01085-8 · Cited by 303
Metadata
- Authors
- Stone, S. L., Kwong, L. W., Yee, K. M., Pelletier, J., Lepiniec, L., Fischer, R. L., Goldberg, R. B., & Harada, J. J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2001-09-25
- Volume
- 98
- Issue
- 20
- Pages
- 11806-11811
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2066228716
- Cited by
- 786
- References
- 2
- FWCI
- 23.40
- Type
- journal article
- Language
- en
- Open access
- green
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- Stone, S. L., Kwong, L. W., Yee, K. M., Pelletier, J., Lepiniec, L., Fischer, R. L., Goldberg, R. B., & Harada, J. J. (2001). LEAFY COTYLEDON2 encodes a B3 domain transcription factor that induces embryo development. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.201413498
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