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Synergistic potential of immune checkpoint inhibitors and therapeutic cancer vaccines

Oladejo, M., Paulishak, W., & Wood, L. M. (2022) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2022.12.003 · Cited by 74 · see citing works

Advances in targeting tumor microenvironment for immunotherapy

Wang, L., Zhang, L., Zhang, Z., Wu, P., Zhang, Y., & Chen, X. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1472772 · Cited by 72 · see citing works

Revisiting regulatory T cells as modulators of innate immune response and inflammatory diseases

Ou, Q., Power, R., & Griffin, M. D. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1287465 · Cited by 71 · see citing works

Current Progress and Future Perspectives of Immune Checkpoint in Cancer and Infectious Diseases

Cai, X., Zhan, H., Ye, Y., Yang, J., Zhang, M., Li, J., & Zhuang, Y. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.785153 · Cited by 66 · see citing works

Biomaterial-mediated macrophage polarization remodeling and sequential regulation: a potential strategy in bone infections treatment

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Investigating the Dynamic Interplay Between Cellular Immunity and Tumor Cells in the Fight Against Cancer: An Updated Comprehensive Review

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IL-23 stabilizes an effector Treg cell program in the tumor microenvironment

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Metabolism Characteristics of Th17 and Regulatory T Cells in Autoimmune Diseases

Qin, Y., Gao, C., & Luo, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.828191 · Cited by 62 · see citing works

Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions

Mei, S., Alchahin, A. M., Τσέα, Ι., Kfoury, Y. S., Hirz, T., Jeffries, N. E., Zhao, T., Xu, Y., Zhang, H., Sarkar, H., et al. (2024) · Genome Medicine · doi:10.1186/s13073-023-01272-6 · Cited by 56 · see citing works

CD74 supports accumulation and function of regulatory T cells in tumors

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Gnawing Between Cells and Cells in the Immune System: Friend or Foe? A Review of Trogocytosis

Zhao, S., Zhang, L., Xiang, S., Hu, Y., Wu, Z., & Shen, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.791006 · Cited by 58 · see citing works

Regulatory T Cell Dysfunction in Autoimmune Diseases

Honing, D. Y., Luiten, R. M., & Matos, T. R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137171 · Cited by 58 · see citing works

Cytolytic CD4+ and CD8+ Regulatory T-Cells and Implications for Developing Immunotherapies to Combat Graft-Versus-Host Disease

Bolivar-Wagers, S., Larson, J. H., Jin, S., & Blazar, B. R. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.864748 · Cited by 56 · see citing works

FOXP3+ regulatory T cells and the immune escape in solid tumours

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Kidney organoids: a pioneering model for kidney diseases

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CTLA-4 tail fusion enhances CAR-T antitumor immunity

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Multi-Layered Mechanisms of Immunological Tolerance at the Maternal-Fetal Interface

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Immune cellular components and signaling pathways in the tumor microenvironment

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T Cells in Atherosclerosis: Key Players in the Pathogenesis of Vascular Disease

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Molecular Mechanisms of Immune Regulation: A Review

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Activated CTLA‐4‐independent immunosuppression of Treg cells disturbs CTLA‐4 blockade‐mediated antitumor immunity

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Role of Treg cell subsets in cardiovascular disease pathogenesis and potential therapeutic targets

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Treg-based immunotherapy for antigen-specific immune suppression and stable tolerance induction: a perspective

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Trogocytosis-mediated immune evasion in the tumor microenvironment

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Regulatory T cells: masterminds of immune equilibrium and future therapeutic innovations

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CTLA4 depletes T cell endogenous and trogocytosed B7 ligands via cis-endocytosis

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Immune evasion in esophageal squamous cell cancer: From the perspective of tumor microenvironment

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Regulatory T cells in autoimmune kidney diseases and transplantation

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Outsmarting trogocytosis to boost CAR NK/T cell therapy

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CTLA-4-expressing ILC3s restrain interleukin-23-mediated inflammation

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From Crypts to Cancer: A Holistic Perspective on Colorectal Carcinogenesis and Therapeutic Strategies

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Soluble CTLA-4 regulates immune homeostasis and promotes resolution of inflammation by suppressing type 1 but allowing type 2 immunity

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Current status of immunotherapy for non-small cell lung cancer

Yang, T., Xiong, Y., Zeng, Y., Wang, Y., Zeng, J., Liu, J., Xu, S., & Li, L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.989461 · Cited by 45 · see citing works

Tregs in transplantation tolerance: role and therapeutic potential

Cassano, A., Chong, A. S., & Alegre, M. (2023) · Frontiers in Transplantation · doi:10.3389/frtra.2023.1217065 · Cited by 44 · see citing works

Roles of Regulatory T Cell-Derived Extracellular Vesicles in Human Diseases

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The effect of Staphylococcus aureus on innate and adaptive immunity and potential immunotherapy for S. aureus-induced osteomyelitis

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Ozone Pollution, Oxidative Stress, Regulatory T Cells and Antioxidants

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IL-10 Negatively Controls the Primary T Cell Response of Tilapia by Triggering the JAK1/STAT3/SOCS3 Axis That Suppresses NF-κB and MAPK/ERK Signaling

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Prevention of Metabolic Syndrome by Phytochemicals and Vitamin D

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Crosstalk between dendritic cells and regulatory T cells: Protective effect and therapeutic potential in multiple sclerosis

Li, R., Li, H., Yang, X., Hu, H., Liu, P., & Liu, H. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.970508 · Cited by 42 · see citing works

Immunometabolism of regulatory T cells in cancer

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CD4+ T-cell subsets in autoimmune hepatitis: A review

Chen, H., Han, Z., Fan, Y., Chen, L., Peng, F., Cheng, X., Wang, Y., Su, J., & Li, D. (2023) · Hepatology Communications · doi:10.1097/hc9.0000000000000269 · Cited by 40 · see citing works

Regulatory T-cells: The Face-off of the Immune Balance

Singer, M., Elsayed, A. M., & Husseiny, M. I. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2911377 · Cited by 39 · see citing works

Implications of regulatory T cells in anti-cancer immunity: from pathogenesis to therapeutics

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Immune checkpoint inhibitors and reproductive failures

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Single-cell transcriptomics reveals variations in monocytes and Tregs between gout flare and remission

Yu, H., Xue, W., Yu, H., Song, Y., Liu, X., Qin, L., Wang, S., Bao, H. F., Gu, H., Chen, G., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.171417 · Cited by 38 · see citing works

Generating functionally stable and antigen-specific T reg cells from effector T cells for cell therapy of inflammatory diseases

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The CTLA‐4 immune checkpoint protein regulates PD‐L1:PD‐1 interaction via transendocytosis of its ligand CD80

Kennedy, A., Robinson, M. A., Hinze, C., Waters, E., Williams, C., Halliday, N., Dovedi, S. J., & Sansom, D. M. (2023) · The EMBO Journal · doi:10.15252/embj.2022111556 · Cited by 36 · see citing works

Tregs integrate native and CAR-mediated costimulatory signals for control of allograft rejection

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IL1RN and PRRX1 as a Prognostic Biomarker Correlated with Immune Infiltrates in Colorectal Cancer: Evidence from Bioinformatic Analysis

Wang, Q., Huang, X., Zhou, S., Ding, Y., Wang, H., Jiang, W., & Xu, M. (2022) · International Journal of Genomics · doi:10.1155/2022/2723264 · Cited by 35 · see citing works

Cell-based therapies for rheumatoid arthritis: opportunities and challenges

Li, Y.-J., & Chen, Z. (2022) · Therapeutic Advances in Musculoskeletal Disease · doi:10.1177/1759720x221100294 · Cited by 34 · see citing works

B7-1 mediates podocyte injury and glomerulosclerosis through communication with Hsp90ab1-LRP5-β-catenin pathway

Li, J., Niu, J., Min, W., Ai, J., Xu, L., Miao, J., Zhou, S. Y., Liang, Y., Chen, S., Ren, Q., et al. (2022) · Cell Death and Differentiation · doi:10.1038/s41418-022-01026-8 · Cited by 34 · see citing works

Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients

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PD-1 and CTLA-4 exert additive control of effector regulatory T cells at homeostasis

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Impact of inflammation and Treg cell regulation on neuropathic pain in spinal cord injury: mechanisms and therapeutic prospects

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Dysregulation of T cell response in the pathogenesis of inflammatory bowel disease

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Spatial multiplex analysis of lung cancer reveals that regulatory T cells attenuate KRAS-G12C inhibitor–induced immune responses

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Mechanisms of Resistance to Anti-PD-1 Immunotherapy in Melanoma and Strategies to Overcome It

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CD40-CD154: A perspective from type 2 immunity

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A mouse model of the LEAP study reveals a role for CTLA-4 in preventing peanut allergy induced by environmental peanut exposure

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Intelligent Nanoplatform Integrating Macrophage and Cancer Cell Membrane for Synergistic Chemodynamic/Immunotherapy/Photothermal Therapy of Breast Cancer

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A coordinated cellular network regulates tolerance to food

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Double Negative T Regulatory Cells: An Emerging Paradigm Shift in Reproductive Immune Tolerance?

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Regulatory T cells in cancer: from immunosuppression to therapeutic targeting

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Clinical and Immunological Effects of p53-Targeting Vaccines

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Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunity

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Functional Diversities of Regulatory T Cells in the Context of Cancer Immunotherapy

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Eras of designer Tregs: Harnessing synthetic biology for immune suppression

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Augmenting regulatory T cells: new therapeutic strategy for rheumatoid arthritis

Zhang, J., Liu, H.-J., Chen, Y.-H., Liu, H., Zhang, S., Yin, G., & Xie, Q.-B. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1312919 · Cited by 25 · see citing works

CTLA-4-dependent trogocytosis promotes the interactions between Tregs and antigen-presenting cells

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Tumor-derived CD4+CD25+regulatory T cells inhibit dendritic cells function by CTLA-4

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CD86 and CD80 Differentially Modulate the Suppressive Function of Human Regulatory T Cells

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Trogocytosis of CD80 and CD86 by induced regulatory T cells

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Activated CTLA‐4‐independent immunosuppression of Treg cells disturbs CTLA‐4 blockade‐mediated antitumor immunity

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