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Receptor-Ligand Interaction Between CD44 and Osteopontin (Eta-1)

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The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques

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A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

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TAM receptors regulate multiple features of microglial physiology

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Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood

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A novel microglial subset plays a key role in myelinogenesis in developing brain

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Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection.

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GABA-Receptive Microglia Selectively Sculpt Developing Inhibitory Circuits

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Phosphorylation‐dependent interaction of osteopontin with its receptors regulates macrophage migration and activation

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Engagement of the Type I Interferon Receptor on Dendritic Cells Inhibits T Helper 17 Cell Development: Role of Intracellular Osteopontin

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Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells

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Engulfment signals and the phagocytic machinery for apoptotic cell clearance

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In-Depth Characterization of Monocyte-Derived Macrophages using a Mass Cytometry-Based Phagocytosis Assay

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CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation

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Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma

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A p85α-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells

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Critical role of integrin CD11c in splenic dendritic cell capture of missing-self CD47 cells to induce adaptive immunity

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Developmental Apoptosis Promotes a Disease-Related Gene Signature and Independence from CSF1R Signaling in Retinal Microglia

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Forebrain microglia from wild-type but not adult 5xFAD mice prevent amyloid-β plaque formation in organotypic hippocampal slice cultures

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RNA-Seq Analysis of Microglia Reveals Time-Dependent Activation of Specific Genetic Programs following Spinal Cord Injury

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Osteopontin expression by CD103 − dendritic cells drives intestinal inflammation

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Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease

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Molecular cascades and cell type–specific signatures in ASD revealed by single-cell genomics

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Microglia maintain structural integrity during fetal brain morphogenesis

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Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

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Microglial diversity in neuropathic pain

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The Role of Osteopontin in Microglia Biology: Current Concepts and Future Perspectives

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Definition of the contribution of an Osteopontin-producing CD11c + microglial subset to Alzheimer’s disease

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Single-cell RNA sequencing reveals the evolution of the immune landscape during perihematomal edema progression after intracerebral hemorrhage

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Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults

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Microglial cannabinoid receptor type II stimulation improves cognitive impairment and neuroinflammation in Alzheimer’s disease mice by controlling astrocyte activation

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A role for microglia in mediating the microbiota–gut–brain axis

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Suppression of inner blood-retinal barrier breakdown and pathogenic Müller glia activation in ischemia retinopathy by myeloid cell depletion

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Myeloid cell replacement is neuroprotective in chronic experimental autoimmune encephalomyelitis

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Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

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Endothelial Foxo1 Phosphorylation Inhibition via Aptamer‐Liposome Alleviates OPN‐Induced Pathological Vascular Remodeling Following Spinal Cord Injury

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Morphine suppresses peripheral responses and transforms brain myeloid gene expression to favor neuropathogenesis in SIV infection

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Microglia in Brain Aging and Age-Related Diseases: Friends or Foes?

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The role of signaling crosstalk of microglia in hippocampus on progression of ageing and Alzheimer's disease

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Neonatal inflammation impairs developmentally-associated microglia and promotes a highly reactive microglial subset

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CD11c ‐Expressing Microglia Are Transient, Driven by Interactions With Apoptotic Cells

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Microglia in early brain development: A window of opportunity

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Botulinum toxin type A-targeted SPP1 contributes to neuropathic pain by the activation of microglia pyroptosis

Chen, L., Gui, X., Tian, W.-D., Kan, H., Huang, J.-Z., & Ji, F. (2024) · World Journal of Psychiatry · doi:10.5498/wjp.v14.i8.1254 · Cited by 12 · see citing works

Detection of disease-associated microglia among various microglia phenotypes induced by West Nile virus infection in mice

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Osteopontin regulation of MerTK+ macrophages promotes Crohn’s disease intestinal fibrosis

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Molecular mapping of a core transcriptional signature of microglia-specific genes in schizophrenia

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Spatiotemporal dynamics of the CD11c+ microglial population in the mouse brain and spinal cord from developmental to adult stages

Nomaki, K., Fujikawa, R., Masuda, T., & Tsuda, M. (2024) · Molecular Brain · doi:10.1186/s13041-024-01098-2 · Cited by 9 · see citing works

Prenatal inflammation impairs early CD11c-positive microglia induction and delays myelination in neurodevelopmental disorders

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Enduring Effects of Humanin on Mitochondrial Systems in TBI Pathology

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New Insights into Roles of IL-7R Gene as a Therapeutic Target Following Intracerebral Hemorrhage

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The Activation of Hippocampal Microglial Cells and Their Role in the Regulation of Pain

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Uncovering transcriptomic landscape alterations of CAN-2409 in in vitro and in vivo glioma models

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Perivascular SPP1 Mediates Microglial Engulfment of Synapses in Alzheimer’s Disease ModelsPreprint

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Transcriptomic Analyses of Brains of RBM8A Conditional Knockout Mice at Different Developmental Stages Reveal Conserved Signaling Pathways Contributing to Neurodevelopmental Diseases

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Smoothened-mediated signaling contributes to immune and non-immune functions of microglia

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Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage

Gai, C., Zhao, Y., Xin, D., Li, T., Cheng, Y., Jiang, Z., Song, Y. Y., Liu, D., & Wang, Z. (2023) · Cells · doi:10.3390/cells12060854 · Cited by 4 · see citing works

Age-related cerebral amyloid angiopathy accumulation in the APPSw mouse model is associated with perivascular inflammation and brain-wide vascular and inflammatory gene and protein changes

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Deficiency of Microglial‐Derived Spp1 Exacerbates Age‐Related Memory Decline by Impairing Mitochondrial Complex I Function

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Microglial Phagocytosis During Embryonic and Postnatal Development

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CD11c+ microglia: From basic research to clinical application

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Absence of Aquaporin-4 (AQP4) Prolongs the Presence of a CD11c+ Microglial Population during Postnatal Corpus Callosum Development

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Anti–IL-6R antibody treatment changes microglial phenotype in AQP4 peptide–immunized mice, leading to suppression of myelitis severity

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Novel diagnostic biomarkers associated with macrophage-microglia in spinal cord injury

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Ectopic CD11c Drives SMAD3-Mediated Aberrant Antigen Presentation and Epithelial–Mesenchymal Transition in Esophageal Squamous Cell Carcinoma

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Spatial proteomic analysis of antimicrobial therapeutic-releasing intracortical probes as a platform technology to modulate specific neuroinflammatory pathways

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Emergence of microglia structural and functional heterogeneity between hippocampal subregions during development into early adulthoodPreprint

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PLCγ2 deficiency compromises systemic immune tolerance and erodes myelin homeostasis while enhancing oxidative metabolism in the mouse brain

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Single-cell RNA sequencing reveals the evolution of the immune landscape during perihematomal edema progression after intracerebral hemorrhagePreprint

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Additional file 6 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S.-H., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972873

Additional file 7 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S.-H., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972876

Additional file 8 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S.-H., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972879

Additional file 9 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S.-H., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972882

Additional file 11 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S.-H., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972888

Additional file 10 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S.-H., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972885

Additional file 5 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S.-H., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972870

Smoothened-mediated signaling contributes to immune and non-immune functions of microgliaPreprint

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Bibliometric Mapping of Research Trends and Hotspots of Microglia in Spinal Cord Injury (2000–2024)

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Identification and validation of PANoptosis-related genes in Alzheimer's disease

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Additional file 3 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972861

Additional file 2 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972855

Additional file 4 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972864

Additional file 1 of Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Ocañas, S. R., Pham, K. D., Cox, J. E. J., Keck, A. W., Ko, S., Ampadu, F. A., Porter, H. L., Ansere, V. A., Kulpa, A. M., Kellogg, C. M., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23972852

Mechanisms controlling microglial colonization of the forebrain

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Identification of a CD44-dependent control of astrocytic autophagic activity in Alzheimer’s disease

Wang, H., Long, Y., Tang, Y., Duan, L., Wang, Z., Zhang, S., Yin, Y., Zhou, J., Wu, W., & Zhong, C. (2026) · The Journal of Prevention of Alzheimer s Disease · doi:10.1016/j.tjpad.2026.100601

A-to-I RNA editing profiles and distinct immune responses in myelin oligodendrocyte glycoprotein antibody-positive optic neuritis

Cui, X., Pan, J.-Q., Ding, J., Fu, X., Cheng, F., Zhang, Y., Chen, J., & Zou, W. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1946792

IL-33/ST2 Signaling and Microglial Functional-State Transitions After Spinal Cord Injury: Direct Evidence and Mechanistic Hypotheses

Ma, Z., Lu, Z., Zhou, Z., Wang, T., Zhang, J., Ma, Y., Niu, R., Zhang, L., Deng, J., & Zhao, Y. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27188254

Definition of the contribution of an Osteopontin-producing CD11c + microglial subset to Alzheimer’s disease

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A novel microglial subset plays a key role in myelinogenesis in developing brain

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Microglia promote the proliferation of neural precursor cells by secreting osteopontin

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Osteopontin alters the functional profile of porcine microglia in vitro

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Spatiotemporal dynamics of the CD11c+ microglial population in the mouse brain and spinal cord from developmental to adult stages

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