The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Shifting foci of hematopoiesis during reconstitution from single stem cells
Open accessAbstract
To reveal the early events and dynamics of hematopoietic reconstitution in living animals in real-time, we used bioluminescence imaging to monitor engraftment from single luciferase-labeled hematopoietic stem cells (HSC) in irradiated recipients. Transplanted HSC generated discrete foci in the spleen and bone marrow (BM), at a frequency that correlated with BM compartment size. Initially detected foci could expand locally, seed other sites in BM or spleen, and/or recede with different kinetics. These studies reveal dynamic and variable patterns of engraftment from highly purified HSC and indicate that the final overall contribution of individual HSC to hematopoietic chimerism does not depend on the specific site of initial engraftment and expansion.
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Wright, D. E., Cheshier, S. H., Wagers, A. J., Randall, T. D., Christensen, J. L., & Weissman, I. L. (2001) · Blood · doi:10.1182/blood.v97.8.2278 · Cited by 208
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Cited by
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Self-renewal and expansion of single transplanted muscle stem cells
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Wilhelm, K., Ganesan, J., Müller, T., Dürr, C., Grimm, M., Beilhack, A., Krempl, C. D., Sorichter, S., Gerlach, U. V., Jüttner, E., et al. (2010) · Nature Medicine · doi:10.1038/nm.2242 · Cited by 435
Self-citationZeiser, R., Leveson-Gower, D. B., Zambricki, E. A., Kambham, N., Beilhack, A., Loh, J., Hou, J.-Z., & Negrin, R. S. (2008) · Blood · doi:10.1182/blood-2007-06-094482 · Cited by 402
Self-citationMolecular Signatures of Quiescent, Mobilized and Leukemia-Initiating Hematopoietic Stem Cells
Forsberg, E. C., Passegué, E., Prohaska, S. S., Wagers, A. J., Koeva, M., Stuart, J. M., & Weissman, I. L. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008785 · Cited by 127
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Metadata
- Authors
- Cao, Y.-A., Wagers, A. J., Beilhack, A., Dusich, J., Bachmann, M. H., Negrin, R. S., Weissman, I. L., & Contag, C. H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2003-12-19
- Volume
- 101
- Issue
- 1
- Pages
- 221-226
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2117419072
- Cited by
- 337
- References
- 1
- FWCI
- 9.15
- Type
- journal article
- Language
- en
- Open access
- green
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- Cao, Y.-A., Wagers, A. J., Beilhack, A., Dusich, J., Bachmann, M. H., Negrin, R. S., Weissman, I. L., & Contag, C. H. (2004). Shifting foci of hematopoiesis during reconstitution from single stem cells. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2637010100
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