The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication
Open accessAbstract
Nuclei from secondary mouse-embryo cells contain an activity capable of untwisting closed-circular DNAs containing either negative or positive superhelical turns. The activity has no apparent effect on a closed-circular DNA containing no superhelical turns, and is not due to the combined action of an endonuclease and polynucleotide ligase. The enzyme apparently acts by introducing a single-strand nick into the DNA, forming a DNA-enzyme complex that allows the strands to rotate relative to the helix axis before reversing the reaction and sealing the break. The enzyme might possibly serve as a swivel during DNA replication.
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Burton, K. (1956) · Biochemical Journal · doi:10.1042/bj0620315 · Cited by 14,090
Cited by
Cook, P. R., & Brazell, I. A. (1975) · Journal of Cell Science · doi:10.1242/jcs.19.2.261 · Cited by 486
Topoisomerases as anticancer targets
Delgado, J. L., Hsieh, C.-M., Chan, N.-L., & Hiasa, H. (2018) · Biochemical Journal · doi:10.1042/bcj20160583 · Cited by 481
New Mechanistic and Functional Insights into DNA Topoisomerases
Chen, S. H., Chan, N.-L., & Hsieh, T.-S. (2013) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-061809-100002 · Cited by 369
Metadata
- Authors
- Champoux, J. J., & Dulbecco, R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1972-01
- Volume
- 69
- Issue
- 1
- Pages
- 143-146
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1994135840
- Cited by
- 346
- References
- 1
- FWCI
- 7.42
- Type
- journal article
- Language
- en
- Open access
- green
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- Champoux, J. J., & Dulbecco, R. (1972). An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.69.1.143
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