The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Supercoils in human dna
Abstract
The three-dimensional structure of a double-stranded DNA molecule may be described by distinguishing the helical turns of the DNA duplex from any superhelical turns that might be superimposed upon the duplex turns. There are characteristic changes in the hydrodynamic properties of superhelical DNA molecules when they interact with intercalating agents. The hydrodynamic properties of nuclear structures released by gently lysing human cells are changed by intercalating agents in this characteristic manner. The characteristic changes are abolished by irradiating the cells with γ-rays but may be restored by incubating the cells at 37 °C after irradiation. These results are interpreted as showing that human DNA is supercoiled. A model for the structure of the chromosome is suggested.
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Cites
Kornberg, R. D. (1974) · Science · doi:10.1126/science.184.4139.868 · Cited by 2,650
ACTION OF X-RAYS ON MAMMALIAN CELLS
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Microfluorometric Detection of Deoxyribonucleic Acid Replication in Human Metaphase Chromosomes
Latt, S. A. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.12.3395 · Cited by 827
Interaction between DNA and an Escherichia coli protein ω
Wang, J. C. (1971) · Journal of Molecular Biology · doi:10.1016/0022-2836(71)90334-2 · Cited by 786
On the structure of the folded chromosome of Escherichia coli
Worcel, A., & Burgi, E. (1972) · Journal of Molecular Biology · doi:10.1016/0022-2836(72)90342-7 · Cited by 643
The interaction of closed circular DNA with intercalative dyes
Bauer, W., & Vinograd, J. (1968) · Journal of Molecular Biology · doi:10.1016/0022-2836(68)90286-6 · Cited by 628
Characterization of Macromolecules by Constant Velocity Sedimentation
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Sigal, N., Delius, H., Kornberg, T., Gefter, M. L., & Alberts, B. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.12.3537 · Cited by 358
Champoux, J. J., & Dulbecco, R. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.1.143 · Cited by 346
Actions of radiations on living cells. 2nd edition
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A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
Rao, S. S. P., Huntley, M. H., Durand, N. C., Stamenova, E. K., Bochkov, I. D., Robinson, J. T., Sanborn, A. L., Machol, I., Omer, A. D., Lander, E. S., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.021 · Cited by 9,212
Expression of a β-globin gene is enhanced by remote SV40 DNA sequences
Banerji, J., Rusconi, S., & Schaffner, W. (1981) · Cell · doi:10.1016/0092-8674(81)90413-x · Cited by 1,724
Chromatin Higher-order Structure and Dynamics
Woodcock, C. L., & Ghosh, R. P. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000596 · Cited by 384
The chromosome folding problem and how cells solve it
Dekker, J., & Mirny, L. A. (2024) · Cell · doi:10.1016/j.cell.2024.10.026 · Cited by 112
DNA damage by drugs and radiation: What is important and how is it measured?
Whitaker, S. J. (1992) · European Journal of Cancer · doi:10.1016/0959-8049(92)90432-2 · Cited by 43
Metadata
- Authors
- Cook, P. R., & Brazell, I. A.
- Venue
- Journal of Cell Science
- Publisher
- The Company of Biologists
- Published
- 1975-11-01
- Volume
- 19
- Issue
- 2
- Pages
- 261-279
- ISSN
- 0021-9533 (ISSN-L)
- 1477-9137
- OpenAlex
- W2145381472
- Cited by
- 486
- References
- 16
- FWCI
- 6.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Supercoils in human dna. https://app.cochat.ai/papers/10.1242/jcs.19.2.261
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- Cook, P. R., & Brazell, I. A. (1975). Supercoils in human dna. Journal of Cell Science. https://doi.org/10.1242/jcs.19.2.261
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
