The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens
Open accessAbstract
Several carcinogenic metabolites of the carcinogen 2-acetyl-aminofluorene, especially 2-nitrosofluorene and N -hydroxy-2-aminofluorene, are potent frameshift mutagens for Salmonella typhimurium . 2-Nitrosonaphthalene, 2-nitrosophenanthrene, 4-nitroso- trans -stilbene, 4-nitrosobiphenyl, and 4-nitrosoazobenzene, all of which are metabolites or likely metabolites of carcinogenic aromatic amines, are also potent frameshift mutagens. These compounds may be frameshift mutagens of the class that intercalates into DNA and then reacts covalently with the DNA; various ultimate carcinogens may be of this type. The utility of a set of bacterial strains for detecting carcinogens as mutagens is shown.
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Citations
Cites
Frameshift Mutations and the Genetic Code
Streisinger, G., Okada, Y., Emrich, J., Newton, J., Tsugita, A., Terzaghi, E., & Inouye, M. (1966) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1966.031.01.014 · Cited by 1,400
Cited by
Building Predictive Models in R Using the caret Package
Kuhn, M. (2008) · Journal of Statistical Software · doi:10.18637/jss.v028.i05 · Cited by 8,863
An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens
Ames, B. N., Lee, F. D., & Durston, W. E. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.3.782 · Cited by 1,532
Self-citationIdentifying Environmental Chemicals Causing Mutations and Cancer
Ames, B. N. (1979) · Science · doi:10.1126/science.373122 · Cited by 586
Self-citationMatched Molecular Pairs as a Medicinal Chemistry Tool: Miniperspective
Griffen, E., Leach, A. G., Robb, G. R., & Warner, D. J. (2011) · Journal of Medicinal Chemistry · doi:10.1021/jm200452d · Cited by 282
Metadata
- Authors
- Ames, B. N., Gurney, E. G., Miller, J. A., & Bartsch, H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1972-11
- Volume
- 69
- Issue
- 11
- Pages
- 3128-3132
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2028300606
- Cited by
- 369
- References
- 1
- FWCI
- 11.02
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens. https://app.cochat.ai/papers/10.1073/pnas.69.11.3128
- The paper
- Ames, B. N., Gurney, E. G., Miller, J. A., & Bartsch, H. (1972). Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.69.11.3128
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
