The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Identifying Environmental Chemicals Causing Mutations and Cancer
Abstract
Damage to DNA appears to be the major cause of most cancer and genetic birth defects and may contribute to aging and heart disease as well. The agents that cause this damage must be identified. Many of these agents are natural chemicals present in the human diet as complex mixtures. The tens of thousands of man-made chemicals that have been introduced into the environment in the last few decades must also be tested for their ability to damage DNA. Existing animal tests and human epidemiology alone are inadequate for this task because of time, expense, and the difficulty of dealing with complex mixtures, Newly developed short-term tests, most of them assaying for mutagenicity, are discussed as key tools in identifying environmental mutagens and carcinogens.
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Cites
Ames, B. N., McCann, J., & Yamasaki, E. (1975) · Mutation Research/Environmental Mutagenesis and Related Subjects · doi:10.1016/0165-1161(75)90046-1 · Cited by 7,381
Self-citationDetection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.
McCann, J., Choi, E., Yamasaki, E., & Ames, B. N. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.12.5135 · Cited by 3,323
Self-citationChemical Mutagens. Principles and Methods for Their Detection.
(1974) · Annals of Internal Medicine · doi:10.7326/0003-4819-80-3-439_4 · Cited by 1,454
Chemical induction of sperm abnormalities in mice.
Wyrobek, A. J., & Bruce, W. R. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.11.4425 · Cited by 874
McCann, J., & Ames, B. N. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.3.950 · Cited by 846
Self-citationShort-term tests for carcinogens and mutagens
Hollstein, M., McCann, J., Angelosanto, F. A., & Nichols, W. W. (1979) · Mutation Research/Reviews in Genetic Toxicology · doi:10.1016/0165-1110(79)90014-9 · Cited by 685
Anderson, D. (1978) · FEBS Letters · doi:10.1016/0014-5793(78)81223-x · Cited by 579
Hair dyes are mutagenic: identification of a variety of mutagenic ingredients.
Ames, B. N., Kammen, H. O., & Yamasaki, E. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.6.2423 · Cited by 473
Self-citationYamasaki, E., & Ames, B. N. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.8.3555 · Cited by 471
Self-citationAn evaluation of 6 short-term tests for detecting organic chemical carcinogens
Purchase, I. F., Longstaff, E., Ashby, J., Styles, J. A., Anderson, D., Lefevre, P. A., & Westwood, F. R. (1978) · British Journal of Cancer · doi:10.1038/bjc.1978.132 · Cited by 424
Cited by
Toxicity of Nanomaterials: Exposure, Pathways, Assessment, and Recent Advances
Ganguly, P., Breen, A., & Pillai, S. C. (2018) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.8b00068 · Cited by 341
Fecalase: a model for activation of dietary glycosides to mutagens by intestinal flora
Tamura, G., Gold, C., Ferro-Luzzi, A., & Ames, B. N. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.8.4961 · Cited by 182
Self-citationMutagenic activity of chloramines
Thomas, E. L., Jefferson, M. M., Bennet, J. J., & Learn, D. B. (1987) · Mutation Research/Genetic Toxicology · doi:10.1016/0165-1218(87)90112-1 · Cited by 55
Metadata
- Authors
- Ames, B. N.
- Venue
- Science
- Published
- 1979-05-11
- Volume
- 204
- Issue
- 4393
- Pages
- 587-593
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2002546431
- Cited by
- 586
- References
- 41
- FWCI
- 31.29
- Type
- journal article
- Language
- en
- Open access
- closed
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
