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Influence of diet on survival of mice.
Open accessAbstract
The longevity of mice of the (NZB X NZW)F1 (B/W) strain and the DBA/2f strain of mice is dramatically prolonged by dietary restriction. B/W mice are susceptible to, and die at an early age from, immunocomplex nephritis. Mice of the DBA/2f strain are also relatively short-lived. Restriction of caloric intake prolonged life of B/W mice more than did protein restriction. DBA/2f mice showed prolongation of life when the diet was restricted only with respect to protein. Caloric restriction alone prolonged life less in DBA/2f mice than in B/W mice. These observations show that dietary manipulations have profound effects on immunity functions, including inhibition of the development of life-shortening autoimmune disease.
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“, 2006), inbred strains (Fernandes et al., 1976; Forster et al., 2003; Goodrick et al., 1990; Harrison and Archer, 1987; Turturro et al., 2002), and recombinant inbred strains (Liao et al.”
Background
Metadata
- Authors
- Fernandes, G., Yunis, E. J., & Good, R. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1976-04
- Volume
- 73
- Issue
- 4
- Pages
- 1279-1283
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2062138189
- Cited by
- 264
- References
- 0
- FWCI
- 3.67
- Type
- journal article
- Language
- en
- Open access
- green
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- Fernandes, G., Yunis, E. J., & Good, R. A. (1976). Influence of diet on survival of mice. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.73.4.1279
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