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Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1).
Open accessAbstract
A monoclonal antibody derived by fusion of mouse myeloma cells with spleen cells from a mouse immunized with F9 teratocarcinoma cells is described. This antibody, which reacts with embryonal carcinoma cells of mouse and human origin and with some preimplantation stage mouse embryos, defines an embryonic stage-specific antigen. This stage-specific antigen (SSEA-1) is first detected on blastomeres of 8-cell stage embryos. Trophectodermal cells are transitorily positive; however, each cell in the inner cell mass eventually expresses this antigen.
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Cited by
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Hakomori, S. (1981) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.50.070181.003505 · Cited by 1,644
Protein Glycosylation in Cancer
Stowell, S. R., Ju, T., & Cummings, R. D. (2015) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-012414-040438 · Cited by 873
Generation of Pluripotent Stem Cells from Neonatal Mouse Testis
Kanatsu-Shinohara, M., Inoue, K., Lee, J., Yoshimoto, M., Ogonuki, N., Miki, H., Baba, S., Kato, T., Kazuki, Y., Toyokuni, S., et al. (2004) · Cell · doi:10.1016/j.cell.2004.11.011 · Cited by 814
Andrews, P. W. (1984) · Developmental Biology · doi:10.1016/0012-1606(84)90316-6 · Cited by 806
Role of Glycosylation in Development
Haltiwanger, R. S., & Lowe, J. B. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.074043 · Cited by 757
Metadata
- Authors
- Solter, D., & Knowles, B. B.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1978-11
- Volume
- 75
- Issue
- 11
- Pages
- 5565-5569
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2158343596
- Cited by
- 1,294
- References
- 0
- FWCI
- 9.85
- Type
- journal article
- Language
- en
- Open access
- green
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- Solter, D., & Knowles, B. B. (1978). Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.75.11.5565
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