The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Stimulation of Ca 2+ -dependent neurotransmitter release and presynaptic nerve terminal protein phosphorylation by calmodulin and a calmodulin-like protein isolated from synaptic vesicles
Open accessAbstract
Synaptic vesicles have a Ca 2+ -dependent protein kinase system that may play a role in mediating Ca 2+ -stimulated neurotransmitter release and vesicle function. Calcium's ability to initiate norepinephrine release and protein phosphorylation in synaptic vesicle preparations was shown to be stimulated by the presence of an endogenous heat-stable vesicle protein fraction. The heat stability and characteristics of this endogenous vesicle fraction were similar to those of calmodulin (Ca 2+ -dependent regular protein) isolated from rat and bovine brain. Calmodulin, like endogenous heat-stable vesicle factor, restored calcium's ability to stimulate vesicle neurotransmitter release and protein kinase activity. Calmodulin-like vesicle protein and purified calmodulin were also equally effective in stimulating cyclic nucleotide-dependent phosphodiesterase, further indicating that these two proteins are functionally equivalent. Depolarization-dependent Ca 2+ uptake in intact synaptosomes simultaneously stimulated release of neurotransmitter and phosphorylation of particular synaptic vesicle proteins that were shown in the isolated vesicle preparation to be dependent on Ca 2+ and calmodulin. The results suggest that calcium's effects on neurotransmitter release and presynaptic nerve terminal protein phosphorylation may be mediated by endogenous calmodulin-like proteins.
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Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 317,331
THE ROLE OF CALCIUM IN THE RELEASE OF NEUROTRANSMITTER SUBSTANCES AND HORMONES
RUBIN, R. P. (1970) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06883-8 · Cited by 873
Cyclic 3′,5′-nucleotide phosphodiesterase
Cheung, W. Y. (1970) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(70)90747-3 · Cited by 823
Blaustein, M. P. (1975) · The Journal of Physiology · doi:10.1113/jphysiol.1975.sp010950 · Cited by 553
Brostrom, C. O., Huang, Y. C., Breckenridge, B. M., & Wolff, D. J. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.1.64 · Cited by 545
Calcium dependent phosphodiesterase activity and its activating factor (PAF) from brain
Kakiuchi, S., & Yamazaki, R. (1970) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(70)90199-3 · Cited by 489
Blaustein, M. P., & Goldring, J. M. (1975) · The Journal of Physiology · doi:10.1113/jphysiol.1975.sp010949 · Cited by 387
Cyclic 3′ : 5′-Nucleotide Phosphodiesterase
Lin, Y. M., Liu, Y. P., & Cheung, W. Y. (1974) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)42412-5 · Cited by 379
SCHULMAN, H., & GREENGARD, P. (1978) · Nature · doi:10.1038/271478a0 · Cited by 336
Cyclic Nucleotide-dependent Protein Kinases
Kuo, J. F., & Greengard, P. (1970) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63097-2 · Cited by 335
Cited by
Kennedy, M. B., Bennett, M. K., & Erondu, N. E. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.23.7357 · Cited by 610
Watterson, D. M., Sharief, F., & Vanaman, T. C. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86127-6 · Cited by 586
Kuo, J. F., Andersson, R. G., Wise, B. C., Mackerlova, L., Salomonsson, I., Brackett, N. L., Katoh, N., Shoji, M., & Wrenn, R. W. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.12.7039 · Cited by 567
Bennett, M. K., Erondu, N. E., & Kennedy, M. B. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44239-6 · Cited by 481
Saitoh, T., & Schwartz, J. H. (1985) · The Journal of cell biology · doi:10.1083/jcb.100.3.835 · Cited by 259
Metadata
- Authors
- Delorenzo, R. J., Freedman, S. D., Yohe, W. B., & Maurer, S. C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1979-04
- Volume
- 76
- Issue
- 4
- Pages
- 1838-1842
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2094373300
- Cited by
- 344
- References
- 11
- FWCI
- 15.14
- Type
- journal article
- Language
- en
- Open access
- green
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- Delorenzo, R. J., Freedman, S. D., Yohe, W. B., & Maurer, S. C. (1979). Stimulation of Ca 2+ -dependent neurotransmitter release and presynaptic nerve terminal protein phosphorylation by calmodulin and a calmodulin-like protein isolated from synaptic vesicles. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.76.4.1838
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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