The DOI matches its Crossref record.
Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor.
Open accessAbstract
Fourier analysis of the hydrophobicities of the acetylcholine receptor subunit sequences reveals regions of amphipathic secondary structure. Prediction of a consensus secondary structure based on this analysis and on an empirical prediction method leads to a testable hypothesis about how the ion channel is formed and might function. Knowledge of the three-dimensional structure of acetylcholine receptors is consistent with features of the model proposed and provides some constraints.
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Citations
Cited by
Acetylcholine Receptor: An Allosteric Protein
Changeux, J.-P., Devillers-Thiéry, A., & Chemouilli, P. (1984) · Science · doi:10.1126/science.6382611 · Cited by 623
Modrow, S., Hahn, B. H., Shaw, G. M., Gallo, R. C., Wong-Staal, F., & Wolf, H. (1987) · Journal of Virology · doi:10.1128/jvi.61.2.570-578.1987 · Cited by 441
Hypothesis about the function of membrane-buried proline residues in transport proteins.
Brandl, C. J., & Deber, C. M. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.4.917 · Cited by 337
Functional Expression of a New Pharmacological Subtype of Brain Nicotinic Acetylcholine Receptor
Wada, K., Ballivet, M., Boulter, J., Connolly, J., Wada, E., Deneris, E. S., Swanson, L. W., Heinemann, S., & Patrick, J. (1988) · Science · doi:10.1126/science.2832952 · Cited by 310
Cloning and localization of a conventional kinesin motor expressed exclusively in neurons
Niclas, J., Navone, F., Hom-Booker, N., & Vale, R. D. (1994) · Neuron · doi:10.1016/0896-6273(94)90314-x · Cited by 153
Metadata
- Authors
- Finer-Moore, J., & Stroud, R. M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1984-01
- Volume
- 81
- Issue
- 1
- Pages
- 155-159
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1996916918
- Cited by
- 506
- References
- 0
- FWCI
- 26.40
- Type
- journal article
- Language
- en
- Open access
- green
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- Finer-Moore, J., & Stroud, R. M. (1984). Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.81.1.155
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.