The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2.
Open accessAbstract
Identity of the Epstein-Barr virus (EBV) receptor with the complement receptor type 2 (CR2) was established in three sets of experiments using the monoclonal antibodies, HB-5 and anti-B2, which recognize a Mr 145,000 B-lymphocyte membrane protein that is CR2. First, the rank order for binding of fluoresceinated EBV to four lymphoblastoid cell lines (SB, JY, Raji, and Molt-4) was identical to the rank order for binding of HB-5 and anti-B2 by analytical flow cytometry. Second, pretreatment of cells with HB-5 followed by treatment with goat F(ab')2 fragments to mouse IgG blocked binding of fluoresceinated EBV on SB, a B-lymphoblastoid cell line. Virus attachment was not inhibited by HB-5 alone, second antibody alone, rabbit anti-C3b receptor, or UPC10 (an irrelevant monoclonal antibody). Third, transfer of CR2 from SB to protein A-bearing Staphylococcus aureus particles, to which HB-5 had been absorbed, conferred on them the specific ability to bind 125I-labeled EBV. We conclude that CR2 is the EBV receptor of human B lymphocytes.
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Dimitrov, D. S. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro817 · Cited by 701
Albritton, L. M., Tseng, L., Scadden, D., & Cunningham, J. M. (1989) · Cell · doi:10.1016/0092-8674(89)90134-7 · Cited by 688
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Metadata
- Authors
- Fingeroth, J. D., Weis, J. J., Tedder, T. F., Strominger, J. L., Biro, P. A., & Fearon, D. T.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1984-07
- Volume
- 81
- Issue
- 14
- Pages
- 4510-4514
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1967738350
- Cited by
- 939
- References
- 20
- FWCI
- 21.71
- Type
- journal article
- Language
- en
- Open access
- green
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- Fingeroth, J. D., Weis, J. J., Tedder, T. F., Strominger, J. L., Biro, P. A., & Fearon, D. T. (1984). Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.81.14.4510
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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