The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase.
Open accessAbstract
Polypeptides of Mr 50,000 and 60,000 in isolated synaptic junctions have been compared to polypeptides of corresponding molecular weight in Ca2+/calmodulin-dependent protein kinase II. The polypeptides of corresponding molecular weight from the two preparations were shown by several criteria to be indistinguishable. These criteria included 125I-labeled tryptic/chymotryptic peptide patterns, 32P-labeled proteolytic peptide maps, and crossreactivity on immunoblots using polyclonal and monoclonal antibodies. Furthermore, studies examining the phosphorylation of substrate proteins, by the endogenous synaptic junction kinase and by Ca2+/calmodulin-dependent protein kinase II, indicated that the two enzymes have similar substrate specificities. Since the Mr 50,000 polypeptide present in synaptic junctions is known to be the major postsynaptic density protein, the present results indicate that the major postsynaptic density protein is a component of Ca2+/calmodulin-dependent protein kinase II.
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Cites
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Continuous cultures of fused cells secreting antibody of predefined specificity
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Self-citationKennedy, M. B., & Greengard, P. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.2.1293 · Cited by 297
Self-citationKennedy, M., McGuinness, T., & Greengard, P. (1983) · The Journal of Neuroscience · doi:10.1523/jneurosci.03-04-00818.1983 · Cited by 258
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Cited by
Hayashi, Y., Shi, S.-H., Esteban, J. A., Piccini, A., Poncer, J.-C., & Malinow, R. (2000) · Science · doi:10.1126/science.287.5461.2262 · Cited by 1,524
A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory.
Lisman, J. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.23.9574 · Cited by 1,127
An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation
Malenka, R. C., Kauer, J. A., Perkel, D. J., Mauk, M. D., Kelly, P. T., Nicoll, R. A., & Waxham, M. N. (1989) · Nature · doi:10.1038/340554a0 · Cited by 1,025
Self-citationMiller, S. (1986) · Cell · doi:10.1016/0092-8674(86)90008-5 · Cited by 864
SynGAP: a Synaptic RasGAP that Associates with the PSD-95/SAP90 Protein Family
Kim, J. H., Liao, D., Lau, L.-F., & Huganir, R. L. (1998) · Neuron · doi:10.1016/s0896-6273(00)81008-9 · Cited by 634
Metadata
- Authors
- Kelly, P. T., McGuinness, T. L., & Greengard, P.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1984-02
- Volume
- 81
- Issue
- 3
- Pages
- 945-949
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2081445047
- Cited by
- 384
- References
- 17
- FWCI
- 10.78
- Type
- journal article
- Language
- en
- Open access
- green
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- Kelly, P. T., McGuinness, T. L., & Greengard, P. (1984). Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.81.3.945
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
