X chromosome-linked muscular dystrophy (mdx) in the mouse

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

LYON, M. F. (1961) · Nature · doi:10.1038/190372a0 · Cited by 3,978

Linkage relationship of a cloned DNA sequence on the short arm of the X chromosome to Duchenne muscular dystrophy

Murray, J., Davies, K. E., Harper, P. S., Meredith, L., Mueller, C. R., & Williamson, R. (1982) · Nature · doi:10.1038/300069a0 · Cited by 330

ACID HYDROLASES AS MODELS OF GENETIC CONTROL

Paigen, K. (1979) · Annual Review of Genetics · doi:10.1146/annurev.ge.13.120179.002221 · Cited by 233

Genetic linkage between Becker muscular dystrophy and a polymorphic DNA sequence on the short arm of the X chromosome.

Kingston, H. M., Thomas, N. S. T., Pearson, P. L., Sarfarazi, M., & Harper, P. S. (1983) · Journal of Medical Genetics · doi:10.1136/jmg.20.4.255 · Cited by 90

Chimaera mouse study shows absence of disease in genetically dystrophic muscle

Peterson, A. C. (1974) · Nature · doi:10.1038/248561a0 · Cited by 59

Serum pyruvate kinase in muscle disease and carrier states

Alberts, M. C., & Samaha, F. J. (1974) · Neurology · doi:10.1212/wnl.24.5.462 · Cited by 54

A histological study of muscle from the bar harbor strain of dystrophic mice

Pearce, G. W., & Walton, J. N. (1963) · The Journal of Pathology and Bacteriology · doi:10.1002/path.1700860105 · Cited by 51

Polymorphism of kidney pyruvate kinase in the mouse is determined by a gene, Pk-3, on chromosome 9

Peters, J., Nash, H., Eicher, E. M., & Bulfield, G. (1981) · Biochemical Genetics · doi:10.1007/bf00484007 · Cited by 46

Pyruvate kinase isoenzymes in progressive muscular dystrophy and in acute myocardial infarction

Harano, Y., Adair, R., Vignos, P. J., Miller, M., & Kowal, J. (1973) · Metabolism · doi:10.1016/0026-0495(73)90041-3 · Cited by 41

Creatine Phosphokinase Isoenzymes in Muscle in human Myopathies

Kar, N. C., & Pearson, C. M. (1965) · American Journal of Clinical Pathology · doi:10.1093/ajcp/43.3.207 · Cited by 40

Transcriptome-scale similarities between mouse and human skeletal muscles with normal and myopathic phenotypes

Kho, A. T., Kang, P. B., Kohane, I. S., & Kunkel, L. M. (2006) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-7-23 · Cited by 42

Stem cells from umbilical cord blood differentiate into myotubes and express dystrophin in vitro only after exposure to in vivo muscle environment

Nunes, V. A., Cavaçana, N., Canovas, M., Strauss, B. E., & Zatz, M. (2007) · Biology of the Cell · doi:10.1042/bc20060075 · Cited by 42

Contractile properties of myocardium are altered in dystrophin-deficient mdx mice

Sapp, J. L., Bobet, J., & Howlett, S. E. (1996) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(96)00167-0 · Cited by 42

Evaluation of exon-skipping strategies for Duchenne muscular dystrophy utilizing dystrophin-deficient zebrafish

Berger, J., Berger, S., Jacoby, A. S., Wilton, S. D., & Currie, P. D. (2011) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2011.01260.x · Cited by 42

Impairments in left ventricular mitochondrial bioenergetics precede overt cardiac dysfunction and remodelling in Duchenne muscular dystrophy

Hughes, M. C., Ramos, S. V., Turnbull, P. C., Edgett, B. A., Huber, J. S., Polidovitch, N., Schlattner, U., Backx, P. H., Simpson, J. A., & Perry, C. G. R. (2019) · The Journal of Physiology · doi:10.1113/jp277306 · Cited by 46

Systemic delivery of NEMO binding domain/IKKγ inhibitory peptide to young mdx mice improves dystrophic skeletal muscle histopathology

Reay, D. P., Yang, M. L., Watchko, J. F., Daood, M., O’Day, T. L., Rehman, K. K., D, D. C. G., Robbins, P. D., & Clemens, P. R. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.05.008 · Cited by 41

Preclinical Studies with Umbilical Cord Mesenchymal Stromal Cells in Different Animal Models for Muscular Dystrophy

Zucconi, E., Vieira, N. M., Júnior, C. R. B., Secco, M., Jazedje, T., Valadares, M. C., Suzuki, M. F., Bartolini, P., Vainzof, M., & Zatz, M. (2011) · BioMed Research International · doi:10.1155/2011/715251 · Cited by 41

Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis

Cea, L. A., Puebla, C., Cisterna, B. A., Escamilla, R., Vargas, A. A., Frank, M., Martínez‐Montero, P., Prior, C., Molano, J., Esteban‐Rodríguez, I., et al. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2132-2 · Cited by 41

Mutation-Based Therapeutic Strategies for Duchenne Muscular Dystrophy: From Genetic Diagnosis to Therapy

Nakamura, A. (2019) · Journal of Personalized Medicine · doi:10.3390/jpm9010016 · Cited by 43

Common therapeutic advances for Duchenne muscular dystrophy (DMD)

Salmaninejad, A., Abarghan, Y. J., Qomi, S. B., Bayat, H., Yousefi, M., Azhdari, S., Talebi, S., & Mojarrad, M. (2020) · International Journal of Neuroscience · doi:10.1080/00207454.2020.1740218 · Cited by 41

What ‘We’?

Lawford‐Smith, H. (2015) · Journal of Social Ontology · doi:10.1515/jso-2015-0008 · Cited by 44

The influence of muscle type and dystrophin deficiency on murine expression profiles

Haslett, J. N., Kang, P. B., Han, M., Kho, A. T., Sanoudou, D., Volinski, J., Beggs, A. H., Kohane, I. S., & Kunkel, L. M. (2005) · Mammalian Genome · doi:10.1007/s00335-005-0053-8 · Cited by 41

A Combined Metabolomic and Proteomic Investigation of the Effects of a Failure to Express Dystrophin in the Mouse Heart

Gulston, M. K., Rubtsov, D. V., Atherton, H. J., Clarke, K., Davies, K. E., Lilley, K. S., & Griffin, J. L. (2008) · Journal of Proteome Research · doi:10.1021/pr800070p · Cited by 41

Transduction of satellite cells after prenatal intramuscular administration of lentiviral vectors

MacKenzie, T. C., Kobinger, G. P., Louboutin, J., Radu, A. P., Javazon, E. H., Sena‐Esteves, M., Wilson, J. M., & Flake, A. W. (2004) · The Journal of Gene Medicine · doi:10.1002/jgm.649 · Cited by 41

Bubble Liposomes and Ultrasound Exposure Improve Localized Morpholino Oligomer Delivery into the Skeletal Muscles of Dystrophic mdx Mice

Negishi, Y., Ishii, Y., Shiono, H., Akiyama, S., Sekine, S., Kojima, T., Mayama, S., Kikuchi, T., Hamano, N., Endo‐Takahashi, Y., et al. (2014) · Molecular Pharmaceutics · doi:10.1021/mp4004755 · Cited by 41

Protein turnover is elevated in muscle of mdx mice in vivo

MACLENNAN, P. A., & Edwards, R. H. T. (1990) · Biochemical Journal · doi:10.1042/bj2680795 · Cited by 42

Mechanical activity of small and large intestine in normal and mdx mice: a comparative analysis

Mulè, V., D’Angelo, Tabacchi, Amato, & Serio, R. (1999) · Neurogastroenterology & Motility · doi:10.1046/j.1365-2982.1999.00142.x · Cited by 41

Profound cellular defects attribute to muscular pathogenesis in the rhesus monkey model of Duchenne muscular dystrophy

Ren, S., Fu, X., Guo, W., Bai, R., Li, S., Zhang, T., Liu, J., Wang, Z., Zhao, H., Suo, S., et al. (2024) · Cell · doi:10.1016/j.cell.2024.08.041 · Cited by 41

Facilitated NMDA receptor-mediated synaptic plasticity in the hippocampal CA1 area of dystrophin-deficient mice

Vaillend, C., Ungerer, A., & Billard, J. (1999) · Synapse · doi:10.1002/(sici)1098-2396(199907)33:1 · Cited by 40

Embryonic myosin is a regeneration marker to monitor utrophin-based therapies for DMD

Guiraud, S., Edwards, B., Squire, S. E., Moir, L., Berg, A., Babbs, A., Ramadan, N., Wood, M. J. A., & Davies, K. E. (2018) · Human Molecular Genetics · doi:10.1093/hmg/ddy353 · Cited by 40

Isometric resistance training increases strength and alters histopathology of dystrophin-deficient mouse skeletal muscle

Lindsay, A., Larson, A. A., Verma, M., Ervasti, J. M., & Lowe, D. A. (2018) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00948.2018 · Cited by 40

What is the level of dystrophin expression required for effective therapy of Duchenne muscular dystrophy?

Wells, D. J. (2019) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-019-09535-9 · Cited by 40

Natural History of Cardiomyopathy in Adult Dogs With Golden Retriever Muscular Dystrophy

Guo, L., Soslow, J. H., Bettis, A. K., Nghiem, P. P., Cummings, K. J., Lenox, M., Miller, M. W., Kornegay, J. N., & Spurney, C. F. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.012443 · Cited by 40

Chronic treatment with agents that stabilize cytosolic IκB-α enhances survival and improves resting membrane potential in MDX muscle fibers subjected to chronic passive stretch

Carlson, C. G., Samadi, A. K., & Siegel, A. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.05.003 · Cited by 42

Full-length dystrophin gene transfer to the mdx mouse in utero

Reay, D. P., Bilbao, R., Koppanati, B. M., Cai, L., O’Day, T., Jiang, Z., Zheng, H., Watchko, J. F., & Clemens, P. R. (2008) · Gene Therapy · doi:10.1038/gt.2008.8 · Cited by 40

Early mechanical dysfunction of the diaphragm in the muscular dystrophy with myositis (Ttnmdm) model

Lopez, M. A., Pardo, P. S., Cox, G. A., & Boriek, A. M. (2008) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.16.2008 · Cited by 40

Myogenic NOS and endogenous NO production are defective in colon from dystrophic (mdx) mice

Mulè, F., Vannucchi, M. G., Corsani, L., Serio, R., & Faussone‐Pellegrini, M. S. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.281.5.g1264 · Cited by 40

Myoediting: Toward Prevention of Muscular Dystrophy by Therapeutic Genome Editing

Zhang, Y., Long, C., Bassel‐Duby, R., & Olson, E. N. (2018) · Physiological Reviews · doi:10.1152/physrev.00046.2017 · Cited by 42

Activation of the intramyofibral autophagic-lysosomal system in muscular dystrophy.

Kominami, E., Kunio, I., & Katunuma, N. (1987) · PubMed Central · Cited by 40

Expression profiling in stably regenerating skeletal muscle of dystrophin-deficient mdx mice

Boer, J. M., de Meijer, E. J., Mank, E. M., van Ommen, G. B., & den Dunnen, J. T. (2002) · Neuromuscular Disorders · doi:10.1016/s0960-8966(02)00092-5 · Cited by 40

In Utero Stem Cell Transplantation

Boelig, M. M., & Flake, A. W. (2016) · Stem cell biology and regenerative medicine · doi:10.1007/978-1-4939-3483-6_17 · Cited by 40

Comparative map for mice and humans

Nadeau, J. H., Davisson, M. T., Doolittle, D. P., Grant, P., Hillyard, A. L., Kosowsky, M., & Roderick, T. H. (1991) · Mammalian Genome · doi:10.1007/bf00656504 · Cited by 40

AAV-directed muscular dystrophy gene therapy

Tang, Y. M., Cummins, J. H., Huard, J., & Wang, B. (2010) · Expert Opinion on Biological Therapy · doi:10.1517/14712591003604690 · Cited by 42

Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma

Hosur, V., Kavirayani, A. M., Riefler, J., Carney, L., Lyons, B. L., Gott, B., Cox, G. A., & Shultz, L. D. (2012) · Cancer Genetics · doi:10.1016/j.cancergen.2012.03.005 · Cited by 39

Stra13 regulates oxidative stress mediated skeletal muscle degeneration

Vercherat, C., Chung, T., Yalcin, S., Gülbağcı, N. T., Gopinadhan, S., Ghaffari, S., & Taneja, R. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp383 · Cited by 39

Chemical mutagenesis of the mouse genome: an overview

Guénet, J. (2007) · Springer eBooks · doi:10.1007/978-1-4020-5057-2_2 · Cited by 39

Target selection for antisense oligonucleotide induced exon skipping in the dystrophin gene

Errington, S. J., Mann, C. J., Fletcher, S., & Wilton, S. D. (2003) · The Journal of Gene Medicine · doi:10.1002/jgm.361 · Cited by 39

Recovery from disuse osteopenia coincident to restoration of muscle strength in mdx mice

Anderson, J. E., Lentz, D. L., & Johnson, R. B. (1993) · Bone · doi:10.1016/8756-3282(93)90084-n · Cited by 39

Glial dystrophin-associated proteins, laminin and agrin, are downregulated in the brain of mdx mouse

Nico, B., Tamma, R., Annese, T., Mangieri, D., Luca, A. D., Corsi, P., Benagiano, V., Longo, V., Enrico Crivellato, B., Salmaggi, A., et al. (2010) · Laboratory Investigation · doi:10.1038/labinvest.2010.149 · Cited by 39

Chemical mutagenesis of the mouse genome: an overview

Guénet, J. (2004) · Genetica · doi:10.1007/s10709-004-1442-8 · Cited by 39

Skeletal muscle regeneration after crush injury in dystrophic mdx mice: An autoradiographic study

Grounds, M. D., & McGeachie, J. K. (1992) · Muscle & Nerve · doi:10.1002/mus.880150508 · Cited by 41

Ascorbic acid protects the diaphragm muscle against myonecrosis in mdx mice

Tonon, É., Ferretti, R., Shiratori, J. H., Neto, H. S., Marques, M. J., & Minatel, E. (2011) · Nutrition · doi:10.1016/j.nut.2011.09.013 · Cited by 38

Rbfox1 Downregulation and Altered Calpain 3 Splicing by FRG1 in a Mouse Model of Facioscapulohumeral Muscular Dystrophy (FSHD)

Pistoni, M., Shiue, L., Cline, M., Bortolanza, S., Neguembor, M. V., Xynos, A., Ares, M., & Gabellini, D. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003186 · Cited by 40

Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle

Olthoff, J. T., Lindsay, A., Abo‐Zahrah, R., Baltgalvis, K. A., Patrinostro, X., Belanto, J. J., Yu, D., Perrin, B. J., Garry, D. J., Rodney, G. G., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-07639-3 · Cited by 41

Duchenne muscular dystrophy animal models for high-throughput drug discovery and precision medicine

Wasala, N. B., Chen, S., & Duan, D. (2020) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2020.1718100 · Cited by 40

Abnormalities in brain biochemistry associated with lack of dystrophin: studies of the mdx mouse

Rae, C. D., Griffin, J. L., Blair, D. H., Bothwell, J. H. F., Bubb, W. A., Maitland, A., & Head, S. I. (2002) · Neuromuscular Disorders · doi:10.1016/s0960-8966(01)00253-x · Cited by 38

Immunological hurdles in the path to gene therapy for Duchenne muscular dystrophy

Wells, D. J., Ferrer, A., & Wells, K. E. (2002) · Expert Reviews in Molecular Medicine · doi:10.1017/s146239940200515x · Cited by 38

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy

Pritchard, H. A. T., Pires, P. W., Yamasaki, E., Thakore, P., & Earley, S. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1804593115 · Cited by 38

“Of Mice and Measures”: A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic

Gordish‐Dressman, H., Willmann, R., Pazze, L. D., Kreibich, A. S., van Putten, M., Heydemann, A., Bogdanik, L. P., Lutz, C. M., Davies, K. E., Demonbreun, A. R., et al. (2018) · Journal of Neuromuscular Diseases · doi:10.3233/jnd-180324 · Cited by 38

Regulation of intracellular free calcium in normal and dystrophic mouse cerebellar neurons

Hopf, F. W., & Steinhardt, R. A. (1992) · Brain Research · doi:10.1016/0006-8993(92)90228-2 · Cited by 38

Induction of revertant fibres in the mdx mouse using antisense oligonucleotides

Fall, A., Johnsen, R. D., Honeyman, K., Iversen, P. L., Fletcher, S., & Wilton, S. D. (2006) · Genetic Vaccines and Therapy · doi:10.1186/1479-0556-4-3 · Cited by 38

Effects of calcium on protein turnover of incubated muscles from mdx mice

MACLENNAN, P. A., McArdle, A., & Edwards, R. H. T. (1991) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1991.260.4.e594 · Cited by 38

In situ localisation of single-stranded DNA breaks in nuclei of a subpopulation of cells within regenerating skeletal muscle of the dystrophic mdx mouse

Coulton, G. R., Rogers, B., Strutt, P., Skynner, M. J., & Watt, D. J. (1992) · Journal of Cell Science · doi:10.1242/jcs.102.3.653 · Cited by 38

The membrane hypothesis of duchenne muscular dystrophy: Quest for functional evidence

Hutter, O. F. (1992) · Journal of Inherited Metabolic Disease · doi:10.1007/bf01799615 · Cited by 38

Direct gene transfer into mouse diaphragm

Davis, H. L., & Jasmin, B. J. (1993) · FEBS Letters · doi:10.1016/0014-5793(93)80393-9 · Cited by 38

Histological Methods to Assess Skeletal Muscle Degeneration and Regeneration in Duchenne Muscular Dystrophy

Dubuisson, N., Versele, R., Planchon, C., Selvais, C. M., Noël, L., Abou‐Samra, M., & de Carrizosa, M. A. D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232416080 · Cited by 41

Chondroitin Sulfate Is a Crucial Determinant for Skeletal Muscle Development/Regeneration and Improvement of Muscular Dystrophies

Mikami, T., Koyama, S., Yabuta, Y., & Kitagawa, H. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.336925 · Cited by 38

Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy

Shabanpoor, F., McClorey, G., Saleh, A. F. A., Järver, P., Wood, M. J. A., & Gait, M. J. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku1256 · Cited by 37

Sarcolipin deletion in mdx mice impairs calcineurin signalling and worsens dystrophic pathology

Fajardo, V. A., Chambers, P. J., Juracic, E. S., Rietze, B. A., Gamu, D., Bellissimo, C. A., Kwon, F., Quadrilatero, J., & Tupling, A. R. (2018) · Human Molecular Genetics · doi:10.1093/hmg/ddy302 · Cited by 37

Macrophages in Skeletal Muscle Dystrophies, An Entangled Partner

Théret, M., Saclier, M., Messina, G., & Rossi, F. M. V. (2021) · Journal of Neuromuscular Diseases · doi:10.3233/jnd-210737 · Cited by 41

Duchenne muscular dystrophy trajectory in R-DMDdel52 preclinical rat model identifies COMP as biomarker of fibrosis

Taglietti, V., Kefi, K., Bronisz-Budzyńska, I., Mirciloglu, B., Rodrigues, M., Cardone, N., Coulpier, F., Periou, B., Gentil, C., Goddard, M. A., et al. (2022) · Acta Neuropathologica Communications · doi:10.1186/s40478-022-01355-2 · Cited by 49

Proteomic profiling of animal models mimicking skeletal muscle disorders

Doran, P., Gannon, J. M., O’Connell, K. M., & Ohlendieck, K. (2007) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.200700042 · Cited by 37

Mutation Types and Aging Differently Affect Revertant Fiber Expansion in Dystrophic Mdx and Mdx52 Mice

Echigoya, Y., Lee, J. K., Rodrigues, M., Nagata, T., Tanihata, J., Nozohourmehrabad, A., Panesar, D., Miskew, B., Aoki, Y., & Yokota, T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069194 · Cited by 37

Calcium‐binding proteins in skeletal muscles of the mdx mice: potential role in the pathogenesis of Duchenne muscular dystrophy

Pertille, A., Carvalho, C. L. T. D., Matsumura, C. Y., Neto, H. S., & Marques, M. J. (2009) · International Journal of Experimental Pathology · doi:10.1111/j.1365-2613.2009.00688.x · Cited by 37

HIF Activation and VEGF Overexpression are Coupled with ZO‐1 Up‐phosphorylation in the Brain of Dystrophic MDX Mouse

Nico, B., Mangieri, D., Enrico Crivellato, B., Longo, V., Giorgis, M. D., Capobianco, C., Corsi, P., Benagiano, V., Roncali, L., & Ribatti, D. (2007) · Brain Pathology · doi:10.1111/j.1750-3639.2007.00090.x · Cited by 37

Dynamic distribution of bone marrow-derived mesenchymal stromal cells and change of pathology after infusing into mdx mice

Feng, S., Lu, X., Liu, Z.-S., Zhang, Y.-N., Liu, T.-Y., Li, J.-L., Yu, M., Zeng, Y., & Zhang, C. (2008) · Cytotherapy · doi:10.1080/14653240802020381 · Cited by 37

Degeneration of dystrophic or injured skeletal muscles induces high expression of Galectin-1

Cerri, D. G., Rodrigues, L. C., Stowell, S. R., de Araujo, D. D., Coelho, M. C., Oliveira, S. R., Bizário, J. C. S., Cummings, R. D., Dias‐Baruffi, M., & Costa, M. C. R. (2008) · Glycobiology · doi:10.1093/glycob/cwn079 · Cited by 39

Bmi1 enhances skeletal muscle regeneration through MT1-mediated oxidative stress protection in a mouse model of dystrophinopathy

Foggia, V. D., Zhang, X., Licastro, D., Gerli, M., Phadke, R., Muntoni, F., Mourikis, P., Tajbakhsh, S., Ellis, M. J., Greaves, L. C., et al. (2014) · The Journal of Experimental Medicine · doi:10.1084/jem.20140317 · Cited by 40

Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice

Judge, L. M., Arnett, A. L. H., Banks, G. B., & Chamberlain, J. S. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr433 · Cited by 40

Metabolic profile of dystrophic mdx mouse muscles analyzed with in vitro magnetic resonance spectroscopy (MRS)

Martins-Bach, A. B., Bloise, A. C., Vainzof, M., & Rabbani, S. R. (2012) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2012.04.003 · Cited by 37

Systematic evaluation of 2′-Fluoro modified chimeric antisense oligonucleotide-mediated exon skipping in vitro

Chen, S., Le, B. T., Chakravarthy, M., Kosbar, T. R., & Veedu, R. N. (2019) · Scientific Reports · doi:10.1038/s41598-019-42523-0 · Cited by 37

Decreased mAKAP, ryanodine receptor, and SERCA2a gene expression in mdx hearts

Rohman, M. S., Emoto, N., Takeshima, Y., Yokoyama, M., & Matsuo, M. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.09.005 · Cited by 37

Beneficial versus adverse effects of long‐term use of clenbuterol in mdx mice

Dupont‐Versteegden, E. E., Katz, M. S., & McCarter, R. (1995) · Muscle & Nerve · doi:10.1002/mus.880181216 · Cited by 37

Contractile properties of clenbuterol-treatedmdx muscle are enhanced by low-intensity swimming

Hayes, A., & Williams, D. A. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.82.2.435 · Cited by 37

Murine models of Duchenne muscular dystrophy: is there a best model?

Swiderski, K., & Lynch, G. S. (2021) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00212.2021 · Cited by 37

From Mice to Humans: An Overview of the Potentials and Limitations of Current Transgenic Mouse Models of Major Muscular Dystrophies and Congenital Myopathies

Sztretye, M. T., Szabó, L. Z., Dobrosi, N., Fodor, J., Szentesi, P., Almássy, J., Magyar, Z. É., Dienes, B., & Csernoch, L. J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21238935 · Cited by 36

NF-YA splice variants have different roles on muscle differentiation

Basile, V., Baruffaldi, F., Dolfini, D., Belluti, S., Benatti, P., Ricci, L., Artusi, V., Tagliafico, E., Mantovani, R., Molinari, S., et al. (2016) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2016.02.011 · Cited by 36

Diaphragm: A vital respiratory muscle in mammals

Lessa, T. B., de Abreu, D. K., Bertassoli, B. M., & Ambrósio, C. E. (2016) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2016.03.008 · Cited by 36

The extraocular muscle stem cell niche is resistant to ageing and disease

Formicola, L., Marazzi, G., & Sassoon, D. A. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00328 · Cited by 42

Partial Functional Correction of Xeroderma Pigmentosum Group A Cells by Suppressor tRNA

Panchal, R. G., Wang, S., Mcdermott, J., & Link, C. J. (1999) · Human Gene Therapy · doi:10.1089/10430349950017194 · Cited by 36

Diltiazem and verapamil protect dystrophin‐deficient muscle fibers of MDX mice from degeneration: A potential role in calcium buffering and sarcolemmal stability

Matsumura, C. Y., Pertille, A., de Albuquerque, T. C. P., Neto, H. S., & Marques, M. J. (2009) · Muscle & Nerve · doi:10.1002/mus.21188 · Cited by 36

Decreased Mitochondrial Oxygen Consumption and Antioxidant Enzyme Activities in Skeletal Muscle of Dystrophic Mice after Low-Intensity Exercise

Faist, V., König, J. S., Höger, H., & Elmadfa, I. (2001) · Annals of Nutrition and Metabolism · doi:10.1159/000046707 · Cited by 36

Involvement of Inositol 1,4,5-Trisphosphate in Nicotinic Calcium Responses in Dystrophic Myotubes Assessed by Near-plasma Membrane Calcium Measurement

Basset, O., Boittin, F.-X., Dorchies, O. M., Chatton, J., van Breemen, C., & Rüegg, U. T. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m405054200 · Cited by 36

Gene Replacement Therapies for Duchenne Muscular Dystrophy Using Adeno-Associated Viral Vectors

Seto, J. T., Ramos, J. N., Muir, L. A., Chamberlain, J. S., & Odom, G. L. (2012) · Current Gene Therapy · doi:10.2174/156652312800840603 · Cited by 37

Gender differences in contractile and passive properties of mdx extensor digitorum longus muscle

Hakim, C. H., & Duan, D. (2011) · Muscle & Nerve · doi:10.1002/mus.22275 · Cited by 36

Therapeutic Effects of Mouse Adipose-Derived Stem Cells and Losartan in the Skeletal Muscle of Injured Mdx Mice

Lee, E. M., Kim, A.-Y., Lee, E. H., Park, J., Lee, M., Hwang, M., Kim, C.-Y., Kim, S., & Jeong, K. (2014) · Cell Transplantation · doi:10.3727/096368914x678599 · Cited by 36

Human stem cells as a model for cardiac differentiation and disease

Beqqali, A., van Eldik, W. M., Mummery, C. L., & Passier, R. C. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-8476-0 · Cited by 36

An in vivo and in vitro 1H-magnetic resonance spectroscopy study of mdx mouse brain: Abnormal development or neural necrosis?

Tracey, I., Dunn, J. F., Parkes, H. G., & Radda, G. K. (1996) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(96)00135-9 · Cited by 36

Adenovirus-mediated gene transfer into striated muscles

Acsádi, G., Jani, A., & Massie, B. (1995) · Journal of Molecular Medicine · doi:10.1007/bf00188137 · Cited by 36

The road toward AAV-mediated gene therapy of Duchenne muscular dystrophy

Bengtsson, N. E., Tasfaout, H., & Chamberlain, J. S. (2025) · Molecular Therapy · doi:10.1016/j.ymthe.2025.03.065 · Cited by 36

Pharyngeal Satellite Cells Undergo Myogenesis Under Basal Conditions and Are Required for Pharyngeal Muscle Maintenance

Randolph, M. E., Phillips, B. L., Choo, H. J., Vest, K. E., Vera, Y., & Pavlath, G. K. (2015) · Stem Cells · doi:10.1002/stem.2098 · Cited by 36

Development of Antisense‐Mediated Exon Skipping as a Treatment for Duchenne Muscular Dystrophy

Heemskerk, H., de Winter, C. L., van Ommen, G. B., van Deutekom, J. C. T., & Aartsma-Rus, A. M. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04973.x · Cited by 35

Neuronal Nitric Oxide Synthase-Rescue of Dystrophin/Utrophin Double Knockout Mice does not Require nNOS Localization to the Cell Membrane

Wehling-Henricks, M., & Tidball, J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025071 · Cited by 37

Aberrant Location of Inhibitory Synaptic Marker Proteins in the Hippocampus of Dystrophin-Deficient Mice: Implications for Cognitive Impairment in Duchenne Muscular Dystrophy

Krasowska, E., Zabłocki, K., Górecki, D. C., & Swinny, J. D. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108364 · Cited by 35

Mitochondrial bioenergetic dysfunction in the D2.mdx model of Duchenne muscular dystrophy is associated with microtubule disorganization in skeletal muscle

Ramos, S. V., Hughes, M. C., Delfinis, L. J., Bellissimo, C. A., & Perry, C. G. R. (2020) · PLoS ONE · doi:10.1371/journal.pone.0237138 · Cited by 35

Empowering Muscle Stem Cells for the Treatment of Duchenne Muscular Dystrophy

Filippelli, R. L., & Chang, N. C. (2021) · Cells Tissues Organs · doi:10.1159/000514305 · Cited by 38

Metformin Increases Sarcolemma Integrity and Ameliorates Neuromuscular Deficits in a Murine Model of Duchenne Muscular Dystrophy

Dong, X., Hui, T., Chen, J., Zheng, Y., Ren, D., Zou, S., Wang, S., Fei, E., Jiao, H., & Lai, X. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.642908 · Cited by 35

Breathing in Duchenne muscular dystrophy: translation to therapy

Mhandire, D. Z., Burns, D. P., Roger, A. L., O’Halloran, K. D., & ElMallah, M. K. (2022) · The Journal of Physiology · doi:10.1113/jp281671 · Cited by 37

Engraftment of ES-Derived Myogenic Progenitors in a Severe Mouse Model of Muscular Dystrophy

Filareto, A. (2012) · Journal of Stem Cell Research & Therapy · doi:10.4172/2157-7633.s10-001 · Cited by 35

Dystrophin Deficiency Compromises Force Production of the Extensor Carpi Ulnaris Muscle in the Canine Model of Duchenne Muscular Dystrophy

Yang, H. T., Shin, J., Hakim, C. H., Pan, X., Terjung, R. L., & Duan, D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044438 · Cited by 35

trophy (mdx) in the mouse

Bulfield, G., Wg, S., Wight, P. A. L., & MOOREt, K. J. (2016)

Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice.

Chapman, V. M., Miller, D. R., Armstrong, D., & Caskey, C. T. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.4.1292 · Cited by 227

X Chromosome-Linked Muscular Dystrophy (mdx) of the Skeletal Muscle, Mouse

Tanabe, Y., Woo, M., & Nonaka, I. (1991) · Monographs on pathology of laboratory animals · doi:10.1007/978-3-642-76533-9_22 · Cited by 2

The mapping of a cDNA from the human X-linked Duchenne muscular dystrophy gene to the mouse X chromosome

Brockdorff, N., Cross, G. S., Cavanna, J., Fisher, E., Lyon, M. F., Davies, K. E., & Brown, S. D. M. (1987) · Nature · doi:10.1038/328166a0 · Cited by 66

Localization of the region homologous to the Duchenne muscular dystrophy locus on the mouse X chromosome

Heilig, R., Lemaire‐Vieille, C., Mandel, J., Dandolo, L., Amar, L., & Avner, P. R. (1987) · Nature · doi:10.1038/328168a0 · Cited by 53