X chromosome-linked muscular dystrophy (mdx) in the mouse

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

LYON, M. F. (1961) · Nature · doi:10.1038/190372a0 · Cited by 3,978

Linkage relationship of a cloned DNA sequence on the short arm of the X chromosome to Duchenne muscular dystrophy

Murray, J., Davies, K. E., Harper, P. S., Meredith, L., Mueller, C. R., & Williamson, R. (1982) · Nature · doi:10.1038/300069a0 · Cited by 330

ACID HYDROLASES AS MODELS OF GENETIC CONTROL

Paigen, K. (1979) · Annual Review of Genetics · doi:10.1146/annurev.ge.13.120179.002221 · Cited by 233

Genetic linkage between Becker muscular dystrophy and a polymorphic DNA sequence on the short arm of the X chromosome.

Kingston, H. M., Thomas, N. S. T., Pearson, P. L., Sarfarazi, M., & Harper, P. S. (1983) · Journal of Medical Genetics · doi:10.1136/jmg.20.4.255 · Cited by 90

Chimaera mouse study shows absence of disease in genetically dystrophic muscle

Peterson, A. C. (1974) · Nature · doi:10.1038/248561a0 · Cited by 59

Serum pyruvate kinase in muscle disease and carrier states

Alberts, M. C., & Samaha, F. J. (1974) · Neurology · doi:10.1212/wnl.24.5.462 · Cited by 54

A histological study of muscle from the bar harbor strain of dystrophic mice

Pearce, G. W., & Walton, J. N. (1963) · The Journal of Pathology and Bacteriology · doi:10.1002/path.1700860105 · Cited by 51

Polymorphism of kidney pyruvate kinase in the mouse is determined by a gene, Pk-3, on chromosome 9

Peters, J., Nash, H., Eicher, E. M., & Bulfield, G. (1981) · Biochemical Genetics · doi:10.1007/bf00484007 · Cited by 46

Pyruvate kinase isoenzymes in progressive muscular dystrophy and in acute myocardial infarction

Harano, Y., Adair, R., Vignos, P. J., Miller, M., & Kowal, J. (1973) · Metabolism · doi:10.1016/0026-0495(73)90041-3 · Cited by 41

Creatine Phosphokinase Isoenzymes in Muscle in human Myopathies

Kar, N. C., & Pearson, C. M. (1965) · American Journal of Clinical Pathology · doi:10.1093/ajcp/43.3.207 · Cited by 40

A- and B-utrophin Have Different Expression Patterns and Are Differentially Up-regulated in mdx Muscle

Weir, A. P., Burton, E. A., Harrod, G. V., & Davies, K. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205177200 · Cited by 131

Muscular dystrophy in the mdx mouse is a severe myopathy compounded by hypotrophy, hypertrophy and hyperplasia

Duddy, W. J., Duguez, S., Johnston, H., Cohen, T. V., Phadke, A., Gordish‐Dressman, H., Nagaraju, K., Gnocchi, V. F., Low, S., & Partridge, T. A. (2015) · Skeletal Muscle · doi:10.1186/s13395-015-0041-y · Cited by 136

Chapter 9 The Value of Mammalian Models for Duchenne Muscular Dystrophy in Developing Therapeutic Strategies

Banks, G. B., & Chamberlain, J. S. (2008) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(08)00609-1 · Cited by 132

Cromolyn administration (to block mast cell degranulation) reduces necrosis of dystrophic muscle in mdx mice

Radley‐Crabb, H. G., & Grounds, M. D. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2006.03.016 · Cited by 129

Distinctive patterns of basic fibroblast growth factor (bFGF) distribution in degenerating and regenerating areas of dystrophic (mdx) striated muscles

Anderson, J. E., Liu, L., & Kardami, E. (1991) · Developmental Biology · doi:10.1016/s0012-1606(05)80010-7 · Cited by 129

Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy

Rooney, J. E., Gurpur, P. B., & Burkin, D. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811599106 · Cited by 128

Detection of dystrophin in the postsynaptic density of rat brain and deficiency in a mouse model of Duchenne muscular dystrophy.

Kim, T. W., Wu, K., Xu, J., & Black, I. B. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.23.11642 · Cited by 128

Collagen content does not alter the passive mechanical properties of fibrotic skeletal muscle in mdx mice

Smith, L., & Barton, E. R. (2014) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00383.2013 · Cited by 127

Creatine supplementation reduces skeletal muscle degeneration and enhances mitochondrial function in mdx mice

Passaquin, A., Renard, M., Kay, L., Challet, C., Mokhtarian, A., Wallimann, T., & Rüegg, U. T. (2002) · Neuromuscular Disorders · doi:10.1016/s0960-8966(01)00273-5 · Cited by 127

Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer

Cerletti, M., Negri, T., Cozzi, F., Colpo, R., Andreetta, F., Croci, D., Davies, K. E., Cornelio, F., Pozza, O., Karpati, G., et al. (2003) · Gene Therapy · doi:10.1038/sj.gt.3301941 · Cited by 126

Muscle-Specific SIRT1 Gain-of-Function Increases Slow-Twitch Fibers and Ameliorates Pathophysiology in a Mouse Model of Duchenne Muscular Dystrophy

Chalkiadaki, A., Igarashi, M., Nasamu, A. S., Knezevic, J., & Guarente, L. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004490 · Cited by 126

Severe cardiomyopathy in mice lacking dystrophin and MyoD

Megeney, L. A., Kablar, B., Perry, R. L., Ying, C., May, L. L., & Rudnicki, M. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.1.220 · Cited by 126

Canine X-Linked Muscular Dystrophy in Japan (CXMDJ).

Shimatsu, Y., KATAGIRI, K., FURUTA, T., Nakura, M., Tanioka, Y., Yuasa, K., Tomohiro, M., Kornegay, J. N., Nonaka, I., & Takeda, S. (2003) · EXPERIMENTAL ANIMALS · doi:10.1538/expanim.52.93 · Cited by 125

Oxidative Stress and the Pathogenesis of Muscular Dystrophies

Rando, T. A. (2002) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/00002060-200211001-00018 · Cited by 125

The association of cardiac muscle necrosis and inflammation with the degenerative and persistent myopathy of MDX mice

Bridges, L. (1986) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(86)90003-1 · Cited by 124

A gene for familial juvenile nephronophthisis (recessive medullary cystic kidney disease) maps to chromosome 2p

Antignac, C., Arduy, C. H., Beckmann, J. S., Benessy, F., Gros, F., Medhioub, M., Hildebrandt, F., Dufier, J., Kleinknecht, C., Broyer, M., et al. (1993) · Nature Genetics · doi:10.1038/ng0493-342 · Cited by 124

Muscle Lesions Associated with Dystrophin Deficiency in Neonatal Golden Retriever Puppies

Nguyen, F., Chérel, Y., Guigand, L., Goubault-Leroux, I., & Wyers, M. (2002) · Journal of Comparative Pathology · doi:10.1053/jcpa.2001.0526 · Cited by 123

CRISPR-Based Gene Therapies: From Preclinical to Clinical Treatments

Laurent, M., Geoffroy, M., Pavani, G., & Guiraud, S. (2024) · Cells · doi:10.3390/cells13100800 · Cited by 126

Canine and feline models of human inherited muscle diseases

Shelton, G. D., & Engvall, E. (2005) · Neuromuscular Disorders · doi:10.1016/j.nmd.2004.10.019 · Cited by 122

Targeted expression of insulin-like growth factor-i reduces early myofiber necrosis in dystrophic mdx mice

Shavlakadze, T., White, J. D., Hoh, J. F. Y., Rosenthal, N. A., & Grounds, M. D. (2004) · Molecular Therapy · doi:10.1016/j.ymthe.2004.07.026 · Cited by 124

Human Ornithine Transcarbamylase Locus Mapped to Band Xp21.1 Near the Duchenne Muscular Dystrophy Locus

Lindgren, V., de Martinville, B., Horwich, A. L., Rosenberg, L. E., & Francke, U. (1984) · Science · doi:10.1126/science.6494904 · Cited by 122

Improved gene transfer by direct plasmid injection associated with regeneration in mouse skeletal muscle

Wells, D. J. (1993) · FEBS Letters · doi:10.1016/0014-5793(93)80508-r · Cited by 121

Dystrophin Dp71: The Smallest but Multifunctional Product of the Duchenne Muscular Dystrophy Gene

Tadayoni, R., Rendón, Á., Soria-Jasso, L. E., & Cisneros, B. (2011) · Molecular Neurobiology · doi:10.1007/s12035-011-8218-9 · Cited by 120

CD82 Is a Marker for Prospective Isolation of Human Muscle Satellite Cells and Is Linked to Muscular Dystrophies

Alexander, M. S., Rozkalne, A., Colletta, A., Spinazzola, J. M., Johnson, S., Rahimov, F., Meng, H., Lawlor, M. W., Estrella, E. A., Kunkel, L. M., et al. (2016) · Cell stem cell · doi:10.1016/j.stem.2016.08.006 · Cited by 120

Flk-1 + Adipose-Derived Mesenchymal Stem Cells Differentiate into Skeletal Muscle Satellite Cells and Ameliorate Muscular Dystrophy in MDX Mice

Liu, Y., Yan, X., Sun, Z., Chen, B., Han, Q., Li, J., & Zhao, R. C. (2007) · Stem Cells and Development · doi:10.1089/scd.2006.0118 · Cited by 123

Skeletal Muscle Function

Cardinet, G. H. (1997) · Elsevier eBooks · doi:10.1016/b978-012396305-5/50017-8 · Cited by 119

Effect of chloroquine-induced myopathy on rat soleus muscle sarcoplasm and expression of clathrin

Kumamoto, T., Nagao, S., Sugihara, R., Abe, T., Ueyama, H., & Tsuda, T. (1998) · Muscle & Nerve · doi:10.1002/(sici)1097-4598(199805)21:5 · Cited by 9

The Dystrophin‐Glycoprotein Complex in the Prevention of Muscle Damage

Gumerson, J., & Michele, D. E. (2011) · BioMed Research International · doi:10.1155/2011/210797 · Cited by 122

Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy

Zhang, K., Zhang, Y., Gu, L., Lan, M., Liu, C., Wang, M., Su, Y., Ge, M., Wang, T., Yu, Y., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-07638-4 · Cited by 117

Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy

Jiang, C., Wen, Y., Kuroda, K., Hannon, K., Rudnicki, M. A., & Kuang, S. (2014) · Disease Models & Mechanisms · doi:10.1242/dmm.015917 · Cited by 116

Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy

Reyes, N. L., Banks, G. B., Tsang, M., Margineantu, D. H., Gu, H., Djukovic, D., Chan, J. I. S., Torres, M., Liggitt, H. D., Hirenallur-Shanthappa, D. K., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1413021112 · Cited by 116

Contractile properties and susceptibility to exercise-induced damage of normal and mdx mouse tibialis anterior muscle

Sacco, P., Jones, D. A., Dick, J. R. T., & Vrbovà, G. (1992) · Clinical Science · doi:10.1042/cs0820227 · Cited by 116

Widespread Distribution and Muscle Differentiation of Human Fetal Mesenchymal Stem Cells After Intrauterine Transplantation in Dystrophic mdx Mouse

Chan, J. K. Y., Waddington, S. N., O’Donoghue, K., Kurata, H., Guillot, P. V., Gotherstrom, C. O. T., Themis, M., Morgan, J. E., & Fisk, N. M. (2006) · Stem Cells · doi:10.1634/stemcells.2006-0694 · Cited by 117

mdx muscle pathology is independent of nNOS perturbation

Crosbie, R. H. (1998) · Human Molecular Genetics · doi:10.1093/hmg/7.5.823 · Cited by 114

The dystrophin associated protein complex in zebrafish

Guyon, J. R., Mosley, A. N., Zhou, Y., O'Brien, K., Sheng, X., Chiang, K., Davidson, A. J., Volinski, J., Zon, L. I., & Kunkel, L. M. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg071 · Cited by 119

Myogenic Expression of Mesenchymal Stem Cells within Myotubes of mdx Mice in Vitro and in Vivo

Saito, T., Dennis, J. E., Lennon, D. P., Young, R. G., & Caplan, A. I. (1995) · Tissue Engineering · doi:10.1089/ten.1995.1.327 · Cited by 114

A New Immuno-, Dystrophin-Deficient Model, the NSG-mdx 4Cv Mouse, Provides Evidence for Functional Improvement Following Allogeneic Satellite Cell Transplantation

Arpke, R. W., Darabi, R., Mader, T. L., Zhang, Y., Toyama, A., Lonetree, C.-L., Nash, N. L., Lowe, D. A., Perlingeiro, R. C. R., & Kyba, M. (2013) · Stem Cells · doi:10.1002/stem.1402 · Cited by 113

Mammalian Models of Duchenne Muscular Dystrophy: Pathological Characteristics and Therapeutic Applications

Nakamura, A., & Takeda, S. (2011) · BioMed Research International · doi:10.1155/2011/184393 · Cited by 120

Osteopontin and skeletal muscle myoblasts: Association with muscle regeneration and regulation of myoblast function in vitro

Uaesoontrachoon, K., Yoo, H.-J., Tudor, E. M., Pike, R. N., Mackie, E. J., & Pagel, C. N. (2008) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2008.03.020 · Cited by 113

Transgenic Expression of α7β1 Integrin Maintains Muscle Integrity, Increases Regenerative Capacity, Promotes Hypertrophy, and Reduces Cardiomyopathy in Dystrophic Mice

Burkin, D. J., Wallace, G. Q., Milner, D. J., Chaney, E. J., Mulligan, J. A., & Kaufman, S. J. (2005) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)62249-3 · Cited by 113

PGC-1α Induces SPP1 to Activate Macrophages and Orchestrate Functional Angiogenesis in Skeletal Muscle

Rowe, G. C., Raghuram, S., Jang, C., Nagy, J. A., Patten, I. S., Goyal, A., Chan, M. C., Liu, L. X., Jiang, A., Spokes, K., et al. (2014) · Circulation Research · doi:10.1161/circresaha.115.303829 · Cited by 115

Spinal muscular atrophy: Recent advances and future prospects

Nicole, S., Cifuentes-Díaz, C., Frugier, T., & Melki, J. (2002) · Muscle & Nerve · doi:10.1002/mus.10110 · Cited by 112

Ultrastructure of the skeletal muscle in the X chromosome-linked dystrophic (mdx) mouse

Cullen, M. J., & Jaros, E. (1988) · Acta Neuropathologica · doi:10.1007/bf00688245 · Cited by 112

Absence of α7 integrin in dystrophin-deficient mice causes a myopathy similar to Duchenne muscular dystrophy

Guo, C., Willem, M., Werner, A., Raivich, G., Emerson, M., Neyses, L., & Mayer, U. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl018 · Cited by 111

A Capacitative Calcium Current in Cultured Skeletal Muscle Cells Is Mediated by the Calcium-specific Leak Channel and Inhibited by Dihydropyridine Compounds

Hopf, F. W., Reddy, P., Hong, J. C., & Steinhardt, R. A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.37.22358 · Cited by 111

Functional characteristics of dystrophic skeletal muscle: insights from animal models

Watchko, J. F., O’Day, T. L., & Hoffman, E. P. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01242.2001 · Cited by 114

The Paradox of Muscle Hypertrophy in Muscular Dystrophy

Kornegay, J. N., Childers, M. K., Bogan, D. J., Bogan, J. R., Nghiem, P. P., Wang, J., Fan, Z., Howard, J. F., Schatzberg, S. J., Dow, J. L., et al. (2012) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2011.11.014 · Cited by 112

Influence of dystrophin-gene mutation onmdx mouse behavior. I. Retention deficits at long delays in spontaneous alternation and bar-pressing tasks

Vaillend, C., Rendon, A., Misslin, R., & Ungerer, A. (1995) · Behavior Genetics · doi:10.1007/bf02327580 · Cited by 112

Impaired regeneration of dystrophin-deficient muscle fibers is caused by exhaustion of myogenic cells

Luz, M. A. M., Marques, M. J., & Neto, H. S. (2002) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2002000600009 · Cited by 109

Lipocalin 2: A New Mechanoresponding Gene Regulating Bone Homeostasis

Rucci, N., Capulli, M., Piperni, S. G., Cappariello, A., Lau, P., Frings‐Meuthen, P., Heer, M. A., & Teti, A. M. (2014) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2341 · Cited by 108

Changes in Phospholipid Composition within the Dystrophic Muscle by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Mass Spectrometry Imaging

Touboul, D., Piednoël, H., Voisin, V., de la Porte, S., Brunelle, A., Halgand, F., & Laprévôte, O. (2004) · European Journal of Mass Spectrometry · doi:10.1255/ejms.671 · Cited by 112

Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex

Judge, L. M., Haraguchiln, M., & Chamberlain, J. S. (2006) · Journal of Cell Science · doi:10.1242/jcs.02857 · Cited by 112

Characterization and identification of the inhibitory domain of GDF-8 propeptide

Jiang, M., Liang, L., Wang, S., Ratovitski, T., Holmstrom, J., Barker, C., & Stotish, R. L. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.01.085 · Cited by 109

Muscle regeneration in dystrophin-deficient mdx mice studied by gene expression profiling

Turk, R., Sterrenburg, E., de Meijer, E., van Ommen, G. B., den Dunnen, J. T., & Hoen, P. A. C. ’. (2005) · BMC Genomics · doi:10.1186/1471-2164-6-98 · Cited by 106

Current Understanding of Molecular Pathology and Treatment of Cardiomyopathy in Duchenne Muscular Dystrophy

van Westering, T. L. E., Betts, C., & Wood, M. J. A. (2015) · Molecules · doi:10.3390/molecules20058823 · Cited by 105

Genetics and pathogenesis of malignant hyperthermia

Jurkat‐Rott, K., McCarthy, T. V., & Lehmann‐Horn, F. (2000) · Muscle & Nerve · doi:10.1002/(sici)1097-4598(200001)23:1 · Cited by 290

Systemic Delivery of Allogenic Muscle Stem Cells Induces Long-Term Muscle Repair and Clinical Efficacy in Duchenne Muscular Dystrophy Dogs

Rouger, K., Larcher, T., Dubreil, L., Deschamps, J., Guiner, C. L., Jouvion, G., Delorme, B., Lieubeau, B., Carlus, M., Fornasari, B., et al. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2011.07.022 · Cited by 111

Lipid mapping in human dystrophic muscle by cluster-time-of-flight secondary ion mass spectrometry imaging

Tahallah, N., Brunelle, A., de la Porte, S., & Laprévôte, O. (2007) · Journal of Lipid Research · doi:10.1194/jlr.m700421-jlr200 · Cited by 105

Low intensity training decreases markers of oxidative stress in skeletal muscle of mdx mice

Kaczor, J. J., Hall, J. E., Payne, E. T., & Tarnopolsky, M. A. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.04.003 · Cited by 104

T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse

Farini, A., Meregalli, M., Belicchi, M., Battistelli, M., Parolini, D., D’Antona, G., Gavina, M., Ottoboni, L., Constantin, G., Bottinelli, R., et al. (2007) · The Journal of Pathology · doi:10.1002/path.2213 · Cited by 104

Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance

Buyse, G., der Mieren, G. V., Erb, M., D’hooge, J., Herijgers, P., Verbeken, E. K., Jara, A., den Bergh, A. V., Mertens, L., Courdier-Fruh, I., et al. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn406 · Cited by 103

YY1 regulates skeletal muscle regeneration through controlling metabolic reprogramming of satellite cells

Chen, F., Zhou, J., Li, Y., Zhao, Y. F., Yuan, J., Cao, Y., Wang, L., Zhang, Z., Zhang, B., Wang, C. C., et al. (2019) · The EMBO Journal · doi:10.15252/embj.201899727 · Cited by 103

Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in mdx Mice

Moore, T. M., Lin, A. J., Strumwasser, A. R., Cory, K., Whitney, K. A., Ho, T., Ho, T., Lee, J. L., Rucker, D. H., Nguyen, C. Q., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00690 · Cited by 105

Association of the Dystroglycan Complex Isolated from Bovine Brain Synaptosomes with Proteins Involved in Signal Transduction

Cavaldesi, M., Macchia, G., Barca, S., Defilippi, P., Tarone, G., & Petrucci, T. C. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.721648.x · Cited by 106

Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice

Janssen, P. M. L., Hiranandani, N., Mays, T. A., & Rafael‐Fortney, J. A. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00448.2005 · Cited by 103

Immune Evasion by Muscle-Specific Gene Expression in Dystrophic Muscle

Hartigan-O’Connor, D. J., Kirk, C. J., Crawford, R., Mulé, J. J., & Chamberlain, J. S. (2001) · Molecular Therapy · doi:10.1006/mthe.2001.0496 · Cited by 106

Altered blood–brain barrier development in dystrophic MDX mice

Nico, B., Nicchia, G. P., Frigeri, A., Corsi, P., Mangieri, D., Ribatti, D., Svelto, M., & Roncali, L. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.02.008 · Cited by 102

A Human-Specific Deletion in Mouse Cmah Increases Disease Severity in the mdx Model of Duchenne Muscular Dystrophy

Chandrasekharan, K., Yoon, J. H., Xu, Y., deVries, S., Camboni, M., Janssen, P. M. L., Varki, A. P., & Martin, P. T. (2010) · Science Translational Medicine · doi:10.1126/scitranslmed.3000692 · Cited by 104

Proteolysis results in altered leak channel kinetics and elevated free calcium in mdx muscle

Turner, P., Schultz, R., Ganguly, B. J., & Steinhardt, R. A. (1993) · The Journal of Membrane Biology · doi:10.1007/bf00232023 · Cited by 102

A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys

Andre, M. S., Johnson, M. C., Bansal, P. N., Wellen, J. W., Robertson, A. W., Opsahl, A., Burch, P. M., Bialek, P., Morris, C. A., & Owens, J. M. (2017) · Skeletal Muscle · doi:10.1186/s13395-017-0141-y · Cited by 104

The jam session between muscle stem cells and the extracellular matrix in the tissue microenvironment

Loreti, M., & Sacco, A. (2022) · npj Regenerative Medicine · doi:10.1038/s41536-022-00204-z · Cited by 111

Passive avoidance behaviour deficit in the mdx mouse

Francesco Muntoni, A., Mateddu, A., & Serra, G. (1991) · Neuromuscular Disorders · doi:10.1016/0960-8966(91)90059-2 · Cited by 101

Production of a model for Lesch–Nyhan syndrome in hypoxanthine phosphoribosyltransferase–deficient mice

Wu, C.-L., & Melton, D. W. (1993) · Nature Genetics · doi:10.1038/ng0393-235 · Cited by 101

Muscular weakness in the mdx mouse

Francesco Muntoni, A., Mateddu, A., Marchei, F., Clerk, A., & Serra, G. (1993) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(93)90027-v · Cited by 100

Transplanted primary neonatal myoblasts can give rise to functional satellite cells as identified using the Myf5nlacZl+ mouse

Heslop, L., Beauchamp, J. R., Tajbakhsh, S., BUCKINGHAM, M. E., Partridge, T. A., & Zammit, P. S. (2001) · Gene Therapy · doi:10.1038/sj.gt.3301463 · Cited by 100

Electrotransfer of naked DNA in the skeletal muscles of animal models of muscular dystrophies

Vilquin, J., Kennel, P., Paturneau-Jouas, M., Chapdelaine, P., Boissel, N., Delaère, P., Tremblay, J. P., Scherman, D., Fiszman, M. Y., & Schwartz, K. (2001) · Gene Therapy · doi:10.1038/sj.gt.3301484 · Cited by 100

Modulating Mitophagy in Mitochondrial Disease

Dombi, E., Mortiboys, H., & Poulton, J. (2017) · Current Medicinal Chemistry · doi:10.2174/0929867324666170616101741 · Cited by 100

Characteristics of Skeletal Muscle in Mdx Mutant Mice

de la Porte, S., Morin, S., & Koenig, J. (1999) · International review of cytology · doi:10.1016/s0074-7696(08)60158-8 · Cited by 102

Nanopatterned muscle cell patches for enhanced myogenesis and dystrophin expression in a mouse model of muscular dystrophy

Yang, H. S., Ieronimakis, N. M., Tsui, J. H., Kim, H. N., Suh, K. Y., Reyes, M., & Kim, D. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.10.067 · Cited by 98

Increase in decorin and biglycan in Duchenne Muscular Dystrophy: role of fibroblasts as cell source of these proteoglycans in the disease

Fadić, R., Mezzano, V., Álvarez, K., Cabrera, D., Holmgren, J., & Brandan, E. (2006) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2006.tb00435.x · Cited by 97

Abnormal lipid profile of dystrophic cardiac tissue as demonstrated by one‐ and two‐dimensional magic‐angle spinning 1H NMR spectroscopy

Griffin, J. L., Williams, H. J., Sang, E., & Nicholson, J. K. (2001) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1185 · Cited by 97

Accumulation of collagen and altered fiber‐type ratios as indicators of abnormal muscle gene expression in the mdx dystrophic mouse

Marshall, P., WILLIAMS, P. E., & Goldspink, G. (1989) · Muscle & Nerve · doi:10.1002/mus.880120703 · Cited by 97

Necroptosis mediates myofibre death in dystrophin-deficient mice

Morgan, J. E., Prola, A., Mariot, V., Pini, V., Meng, J., Hourdé, C., Dumonceaux, J., Conti, F. J. A., Relaix, F., Authier, F., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-06057-9 · Cited by 97

Skeletal muscle in health and disease

Morgan, J. E., & Partridge, T. A. (2020) · Disease Models & Mechanisms · doi:10.1242/dmm.042192 · Cited by 98

Cognitive impairment in neuromuscular disorders

D’Angelo, M. G., & Bresolin, N. (2006) · Muscle & Nerve · doi:10.1002/mus.20535 · Cited by 95

Viral-mediated gene therapy for the muscular dystrophies: Successes, limitations and recent advances

Odom, G. L., Gregorevic, P., & Chamberlain, J. S. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2006.09.007 · Cited by 97

Genetic Analyses of Integrin SignalingPreprint

Wickstrom, S. A., Radovanac, K., & Fassler, R. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005116 · Cited by 95

Ca 2+ /Calmodulin-Dependent Kinase IIδ Causes Heart Failure by Accumulation of p53 in Dilated Cardiomyopathy

Toko, H., Takahashi, H., Kayama, Y., Oka, T., Minamino, T., Okada, S., Morimoto, S., Zhan, D., Terasaki, F., Anderson, M. E., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.935296 · Cited by 95

The gene and its product

Mandel, J. (1989) · Nature · doi:10.1038/339584a0 · Cited by 98

Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice

Malerba, A., Sharp, P. S., Graham, I. R., Arechavala‐Gomeza, V., Foster, K., Muntoni, F., Wells, D. J., & Dickson, G. (2010) · Molecular Therapy · doi:10.1038/mt.2010.261 · Cited by 93

RNA-targeted splice-correction therapy for neuromuscular disease

Wood, M. J. A., Gait, M. J., & Yin, H. (2010) · Brain · doi:10.1093/brain/awq002 · Cited by 93

Testing of SHIRPA, a mouse phenotypic assessment protocol, on Dmd mdx and Dmd mdx3cv dystrophin-deficient mice

Rafael, J. A., Nitta, Y., Peters, J., & Davies, K. E. (2000) · Mammalian Genome · doi:10.1007/s003350010149 · Cited by 97

Expansion of revertant fibers in dystrophic mdx muscles reflects activity of muscle precursor cells and serves as an index of muscle regeneration

Yokota, T., Lu, Q., Morgan, J. E., Davies, K. E., Fisher, R., Takeda, S., & Partridge, T. A. (2006) · Journal of Cell Science · doi:10.1242/jcs.03000 · Cited by 93

Skeletal Muscle as a Paradigm for Regenerative Biology and Medicine

Gayraud-Morel, B., Chrétien, F., & Tajbakhsh, S. (2009) · Regenerative Medicine · doi:10.2217/17460751.4.2.293 · Cited by 103

Extensive but Coordinated Reorganization of the Membrane Skeleton in Myofibers of Dystrophic (mdx) Mice

Williams, M. W., & Bloch, R. J. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.144.6.1259 · Cited by 93

Dermal fibroblasts convert to a myogenic lineage in mdx mouse muscle

Gibson, A. J., Karasiński, J., Relvas, J. B., Moss, J., Sherratt, T. G., Strong, P. N., & Watt, D. J. (1995) · Journal of Cell Science · doi:10.1242/jcs.108.1.207 · Cited by 93

Progressive muscular dystrophy in a golden retriever dog: light microscope and ultrastructural features at 4 and 8 months

Valentine, B. A., Cooper, B. J., Cummings, J. F., & deLahunta, A. (1986) · Acta Neuropathologica · doi:10.1007/bf00688053 · Cited by 92

Basic fibroblast growth factor promotes in vivo muscle regeneration in murine muscular dystrophy

Lefaucheur, J. P., & Sébille, A. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(95)12223-0 · Cited by 92

Immunocytochemical study of dystrophin at the myotendinous junction

Samitt, C. E., & Bonilla, E. (1990) · Muscle & Nerve · doi:10.1002/mus.880130605 · Cited by 92

A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9

Sui, T., Lau, Y. S., Liu, D., Liu, T., Xu, L. M., Gao, Y., Lai, L., Li, Z., & Han, R. (2018) · Disease Models & Mechanisms · doi:10.1242/dmm.032201 · Cited by 99

trophy (mdx) in the mouse

Bulfield, G., Wg, S., Wight, P. A. L., & MOOREt, K. J. (2016)

Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice.

Chapman, V. M., Miller, D. R., Armstrong, D., & Caskey, C. T. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.4.1292 · Cited by 227

X Chromosome-Linked Muscular Dystrophy (mdx) of the Skeletal Muscle, Mouse

Tanabe, Y., Woo, M., & Nonaka, I. (1991) · Monographs on pathology of laboratory animals · doi:10.1007/978-3-642-76533-9_22 · Cited by 2

The mapping of a cDNA from the human X-linked Duchenne muscular dystrophy gene to the mouse X chromosome

Brockdorff, N., Cross, G. S., Cavanna, J., Fisher, E., Lyon, M. F., Davies, K. E., & Brown, S. D. M. (1987) · Nature · doi:10.1038/328166a0 · Cited by 66

Localization of the region homologous to the Duchenne muscular dystrophy locus on the mouse X chromosome

Heilig, R., Lemaire‐Vieille, C., Mandel, J., Dandolo, L., Amar, L., & Avner, P. R. (1987) · Nature · doi:10.1038/328168a0 · Cited by 53