The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
An unusual genetic code in nuclear genes of Tetrahymena.
Open accessAbstract
We have cloned and partially sequenced two histone H3 genes of Tetrahymena thermophila. The DNA sequences strongly suggest that both genes are active in the vegetatively growing cell. Comparison of the derived amino acid sequences of these two genes with the actual sequence of Tetrahymena histone H3 results in the surprising conclusion that TAA codes for glutamine. This represents the first demonstration of a coding function for this termination codon of the "universal" code. This observation has important implications for the evolution of ciliates and of the genetic code.
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Citations
Cites
On the evolution of the genetic code.
Woese, C. R. (1965) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.54.6.1546 · Cited by 487
Cited by
The guanine and cytosine content of genomic DNA and bacterial evolution.
Muto, A., & Osawa, S. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.1.166 · Cited by 578
Codon reassignment (codon capture) in evolution
Osawa, S., & Jukes, T. H. (1989) · Journal of Molecular Evolution · doi:10.1007/bf02103422 · Cited by 289
Genetic Codes with No Dedicated Stop Codon: Context-Dependent Translation Termination
Swart, E. C., Serra, V., Petroni, G., & Nowacki, M. (2016) · Cell · doi:10.1016/j.cell.2016.06.020 · Cited by 167
Metadata
- Authors
- Horowitz, S., & Gorovsky, M. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1985-04
- Volume
- 82
- Issue
- 8
- Pages
- 2452-2455
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2050057842
- Cited by
- 223
- References
- 1
- FWCI
- 7.15
- Type
- journal article
- Language
- en
- Open access
- green
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- Horowitz, S., & Gorovsky, M. A. (1985). An unusual genetic code in nuclear genes of Tetrahymena. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.82.8.2452
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