The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat.
Open accessAbstract
Cloned cDNAs encoding the precursor protein for gonadotropin-releasing hormone (Gn-RH) and prolactin release-inhibiting factor (PIF) were isolated from libraries derived from human and rat hypothalamic mRNA. Nucleotide sequence analyses predict precursor proteins of 92 amino acids for both species and show identity between the human placental and human hypothalamic precursor proteins. Whereas the Gn-RH peptide structure is completely conserved in human and rat, the PIF domain of the precursor displays 70% interspecies homology. Genomic analyses revealed the presence of a single Gn-RH-PIF gene in human and rat containing sequences corresponding to the cDNA distributed across four exons.
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Second gene for gonadotropin-releasing hormone in humans
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The Stimulatory Effect of Leptin on the Neuroendocrine Reproductive Axis of the Monkey1
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Metadata
- Authors
- Adelman, J. P., Mason, A. J., Hayflick, J. S., & Seeburg, P. H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1986-01
- Volume
- 83
- Issue
- 1
- Pages
- 179-183
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2117556333
- Cited by
- 349
- References
- 28
- FWCI
- 27.84
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat. https://app.cochat.ai/papers/10.1073/pnas.83.1.179
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- Adelman, J. P., Mason, A. J., Hayflick, J. S., & Seeburg, P. H. (1986). Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.83.1.179
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
