The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Cloning of the cDNA and gene for a human D2 dopamine receptor.
Open accessAbstract
A clone encoding a human D2 dopamine receptor was isolated from a pituitary cDNA library and sequenced. The deduced protein sequence is 96% identical with that of the cloned rat receptor with one major difference: the human receptor contains an additional 29 amino acids in its putative third cytoplasmic loop. Southern blotting demonstrated the presence of only one human D2 receptor gene. Two overlapping phage containing the gene were isolated and characterized. DNA sequence analysis of these clones showed that the coding sequence is interrupted by six introns and that the additional amino acids present in the human pituitary receptor are encoded by a single exon of 87 base pairs. The involvement of this sequence in alternative splicing and its biological significance are discussed.
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Cites
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Cloning and expression of a rat D2 dopamine receptor cDNA
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Cited by
Dopamine receptors: from structure to function
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Prolactin: structure, function, and regulation of secretion
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Multiple dopamine D4 receptor variants in the human population
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Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits
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Metadata
- Authors
- Grandy, D. K., Marchionni, M. A., Makam, H., Stofko, R. E., Alfano, M., Frothingham, L., Fischer, J. B., Burke-Howie, K. J., Bunzow, J. R., & Server, A. C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1989-12
- Volume
- 86
- Issue
- 24
- Pages
- 9762-9766
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2166217068
- Cited by
- 486
- References
- 25
- FWCI
- 12.52
- Type
- journal article
- Language
- en
- Open access
- green
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- Grandy, D. K., Marchionni, M. A., Makam, H., Stofko, R. E., Alfano, M., Frothingham, L., Fischer, J. B., Burke-Howie, K. J., Bunzow, J. R., & Server, A. C. (1989). Cloning of the cDNA and gene for a human D2 dopamine receptor. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.86.24.9762
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
