The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas.
Open accessAbstract
Cas NS-1 is an acutely transforming murine retrovirus that induces pre-B and pro-B cell lymphomas. Molecular cloning showed it was generated from the ecotropic Cas-Br-M virus by sequential recombinations with endogenous retroviral sequences and a cellular oncogene. The oncogene sequence shows no homology with known oncogenes but some similarity to the yeast transcriptional activator GCN4. A 100-kDa gag-cbl fusion protein, with no detectable kinase activity, is responsible for the cellular transformation. The cellular homologue of v-cbl, present in mouse and human DNA, is expressed in a range of hemopoietic lineages.
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Cites
Bohmann, D., Bos, T. J., Admon, A., Nishimura, T., Vogt, P. K., & Tjian, R. (1987) · Science · doi:10.1126/science.2825349 · Cited by 1,321
Cited by
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Bellacosa, A., Testa, J. R., Staal, S. P., & Tsichlis, P. N. (1991) · Science · doi:10.1126/science.1833819 · Cited by 939
The Cbl interactome and its functions
Schmidt, M. H. H., & Dikic, I. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1762 · Cited by 395
Wienands, J., Schweikert, J., Wollscheid, B., Jumaa, H., Nielsen, P. J., & Reth, M. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.4.791 · Cited by 271
Lee, P. S. W., Wang, Y., Dominguez, M. G., Yeung, Y., Murphy, M. A., Bowtell, D. D. L., & Stanley, E. R. (1999) · The EMBO Journal · doi:10.1093/emboj/18.13.3616 · Cited by 255
E3 ubiquitin ligases as T cell anergy factors
Mueller, D. L. (2004) · Nature Immunology · doi:10.1038/ni1106 · Cited by 224
Metadata
- Authors
- Langdon, W. Y., Hartley, J. W., Klinken, S. P., Ruscetti, S. K., & Morse, H. C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1989-02
- Volume
- 86
- Issue
- 4
- Pages
- 1168-1172
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1981096579
- Cited by
- 307
- References
- 1
- FWCI
- 3.53
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas. https://app.cochat.ai/papers/10.1073/pnas.86.4.1168
- The paper
- Langdon, W. Y., Hartley, J. W., Klinken, S. P., Ruscetti, S. K., & Morse, H. C. (1989). v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.86.4.1168
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
