The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
jun-D: a third member of the jun gene family.
Open accessAbstract
The protooncogene c-jun encodes a component of the transcription factor AP-1. Both murine c-jun and a related gene (jun-B) are rapidly activated in BALB/c3T3 cells by serum growth factors. We report here the cloning and analysis of a cDNA encoding a third member of the murine jun family, jun-D. The amino acid sequence encoded by jun-D has two extensive regions of homology with the other Jun proteins. One homology region includes the DNA-binding domain and sequences required for dimer formation and interaction with the Fos oncoprotein; the other includes the acidic sequence thought to be involved in gene activation. All three jun mRNAs are present in a variety of murine tissues and cell lines. In resting 3T3 cells, jun-D is expressed at a higher level compared to c-jun and jun-B, and its transcription is stimulated only slightly by serum growth factors. Thus, jun-D appears to be regulated differently than c-jun and jun-B.
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Citations
Cites
The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins
Landschulz, W. H., Johnson, P. F., & McKnight, S. L. (1988) · Science · doi:10.1126/science.3289117 · Cited by 3,443
Bohmann, D., Bos, T. J., Admon, A., Nishimura, T., Vogt, P. K., & Tjian, R. (1987) · Science · doi:10.1126/science.2825349 · Cited by 1,321
Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.
Lau, L. F., & Nathans, D. (1985) · The EMBO Journal · doi:10.1002/j.1460-2075.1985.tb04057.x · Cited by 567
Self-citation
Cited by
Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.
Cao, Z., Umek, R. M., & McKnight, S. L. (1991) · Genes & Development · doi:10.1101/gad.5.9.1538 · Cited by 1,663
Xanthoudakis, S., & Curran, T. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05097.x · Cited by 708
Li, Y., & Jaiswal, A. K. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42151-5 · Cited by 353
Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3.
Schaefer, T. S., Sanders, L. K., & Nathans, D. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.20.9097 · Cited by 357
Self-citationA direct physical association between ETS and AP-1 transcription factors in normal human T cells
Bassuk, A. G., & Leiden, J. M. (1995) · Immunity · doi:10.1016/1074-7613(95)90092-6 · Cited by 186
Metadata
- Authors
- Ryder, K., Lanahan, A., Perez-Albuerne, E., & Nathans, D.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1989-03
- Volume
- 86
- Issue
- 5
- Pages
- 1500-1503
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2092237565
- Cited by
- 451
- References
- 3
- FWCI
- 20.83
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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