The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Molecular cloning of a human gene that is a member of the nerve growth factor family.
Open accessAbstract
Cell death within the developing vertebrate nervous system is regulated in part by interactions between neurons and their innervation targets that are mediated by neurotrophic factors. These factors also appear to have a role in the maintenance of the adult nervous system. Two neurotrophic factors, nerve growth factor and brain-derived neurotrophic factor, share substantial amino acid sequence identity. We have used a screen that combines polymerase chain reaction amplification of genomic DNA and low-stringency hybridization with degenerate oligonucleotides to isolate human BDNF and a human gene, neurotrophin-3, that is closely related to both nerve growth factor and brain-derived neurotrophic factor. mRNA products of the brain-derived neurotrophic factor and neurotrophin-3 genes were detected in the adult human brain, suggesting that these proteins are involved in the maintenance of the adult nervous system. Neurotrophin-3 is also expected to function in embryonic neural development.
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Cites
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
Trophic factors and neuronal survival
Barde, Y.-A. (1989) · Neuron · doi:10.1016/0896-6273(89)90040-8 · Cited by 1,625
Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF
Maisonpierre, P. C., Belluscio, L., Squinto, S., Ip, N. Y., Furth, M. E., Lindsay, R. M., & Yancopoulos, G. D. (1990) · Science · doi:10.1126/science.2321006 · Cited by 1,322
Hohn, A., Leibrock, J., Bailey, K., & Barde, Y.-A. (1990) · Nature · doi:10.1038/344339a0 · Cited by 1,145
Cited by
trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3
Lamballe, F., Klein, R., & Barbacid, M. (1991) · Cell · doi:10.1016/0092-8674(91)90442-2 · Cited by 1,080
Jones, K. R., Fariñas, I., Backus, C., & Reichardt, L. F. (1994) · Cell · doi:10.1016/0092-8674(94)90377-8 · Cited by 1,042
Self-citationKlein, R., Nanduri, V., Jing, S., Lamballe, F., Tapley, P., Bryant, S., Cordon-Cardo, C., Jones, K. R., Reichardt, L. F., & Barbacid, M. (1991) · Cell · doi:10.1016/0092-8674(91)90628-c · Cited by 958
Self-citationLee, K.-F., Li, E., Huber, L. J., Landis, S. C., Sharpe, A. H., Chao, M. V., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90286-l · Cited by 956
Murer, M. G., Yan, Q., & Raisman-Vozari, R. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00014-9 · Cited by 874
Metadata
- Authors
- Jones, K. R., & Reichardt, L. F.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1990-10
- Volume
- 87
- Issue
- 20
- Pages
- 8060-8064
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2053287079
- Cited by
- 404
- References
- 4
- FWCI
- 14.64
- Type
- journal article
- Language
- en
- Open access
- green
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- Jones, K. R., & Reichardt, L. F. (1990). Molecular cloning of a human gene that is a member of the nerve growth factor family. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.87.20.8060
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