Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

Ullrich, A., Coussens, L. M., Hayflick, J. S., Dull, T. J., Gray, A., Tam, A. W., Lee, J., Yarden, Y., Libermann, T. A., Schlessinger, J., et al. (1984) · Nature · doi:10.1038/309418a0 · Cited by 2,751 · see citing works

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

Fearon, E. R., Cho, K. R., Nigro, J. M., Kern, S. E., Simons, J. W., Ruppert, J. M., Hamilton, S. R., Preisinger, A. C., Thomas, G., Kinzler, K. W., et al. (1990) · Science · doi:10.1126/science.2294591 · Cited by 1,738 · see citing works

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

Libermann, T. A., Nusbaum, H. R., Razon, N., Kris, R., Lax, I., Soreq, H., Whittle, N., Waterfield, M. D., Ullrich, A., & Schlessinger, J. (1985) · Nature · doi:10.1038/313144a0 · Cited by 1,503 · see citing works

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.

Wong, A. J., Bigner, S. H., Bigner, D. D., Kinzler, K. W., Hamilton, S. R., & Vogelstein, B. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.19.6899 · Cited by 849 · see citing works

Autophosphorylation sites on the epidermal growth factor receptor

Downward, J., Parker, P., & Waterfield, M. D. (1984) · Nature · doi:10.1038/311483a0 · Cited by 704 · see citing works

EPIDERMAL-GROWTH-FACTOR RECEPTORS IN HUMAN BLADDER CANCER: COMPARISON OF INVASIVE AND SUPERFICIAL TUMOURS

Neal, D. E., Bennett, M., Hall, R. R., Marsh, C., Abel, P., Sainsbury, J. R. C., & Harris, A. L. (1985) · The Lancet · doi:10.1016/s0140-6736(85)91386-8 · Cited by 604 · see citing works

Clonal genomic alterations in glioma malignancy stages.

Cd, J., Carlbom, E., Dumanski, J. P., Hansen, M., Nordenskjöld, M., Collins, V. P., & Cavenee, W. K. (1988) · PubMed · Cited by 512 · see citing works

Expression of epidermal growth factor receptors in human brain tumors.

Libermann, T. A., Razon, N., Bartal, A. D., Yarden, Y., Schlessinger, J., & Soreq, H. (1984) · PubMed · Cited by 473 · see citing works

Expression Cloning of Human EGF Receptor Complementary DNA: Gene Amplification and Three Related Messenger RNA Products in A431 Cells

Lin, C. R., Chen, W. S., Kruiger, W., et al. (1984) · Science · doi:10.1126/science.6326261 · Cited by 408 · see citing works

Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene.

Ishii, S., Xu, Y. H., Stratton, R. H., et al. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.15.4920 · Cited by 393 · see citing works

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.

Humphrey, P. A., Wong, A. J., Vogelstein, B., Zalutsky, M. R., Fuller, G. N., Archer, G. E., Friedman, H. S., Kwatra, M. M., Bigner, S. H., & Bigner, D. D. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.11.4207 · Cited by 382 · see citing works

Human squamous cell lung cancers express increased epidermal growth factor receptors.

Hendler, F. J., & Ozanne, B. W. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111463 · Cited by 370 · see citing works

Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines.

Nistér, M., Libermann, T. A., Betsholtz, C., et al. (1988) · PubMed · Cited by 355 · see citing works

Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas.

Gullick, W. J., Marsden, J. J., Whittle, N., et al. (1986) · PubMed · Cited by 307 · see citing works

Mitotic recombination of chromosome 17 in astrocytomas.

James, C. D., Carlbom, E., Nordenskjöld, M., Collins, V. P., & Cavenee, W. K. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.8.2858 · Cited by 279 · see citing works

Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts.

Humphrey, P. A., Wong, A. J., Vogelstein, B., et al. (1988) · PubMed · Cited by 265 · see citing works

Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines.

Xu, Y. H., Richert, N. D., Ito, S., Merlino, G. T., & Pastan, I. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.23.7308 · Cited by 225 · see citing works

Gene Amplification in Malignant Human Gliomas: Clinical and Histopathologic Aspects

Bigner, S. H., Burger, P. C., Wong, A. J., et al. (1988) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-198805000-00001 · Cited by 213 · see citing works

Amplification of the Structurally and Functionally Altered Epidermal Growth Factor Receptor Gene (c-erbB) in Human Brain Tumors

Yamazaki, H., Fukui, Y., Ueyama, Y., Tamaoki, N., Kawamoto, T., Taniguchi, S., & Shibuya, M. (1988) · Molecular and Cellular Biology · doi:10.1128/mcb.8.4.1816 · Cited by 211 · see citing works

Epidermal growth factor, its receptor, and related proteins

Carpenter, G. F., & Zendegui, J. G. (1986) · Experimental Cell Research · doi:10.1016/0014-4827(86)90449-0 · Cited by 187 · see citing works

Effects of preparatory patient education for radiation oncology patients

Rainey, L. C. (1985) · Cancer · doi:10.1002/1097-0142(19850901)56:5 · Cited by 174 · see citing works

Epidermal growth factor binding induces a conformational change in the external domain of its receptor.

Greenfield, C., Hiles, I., Waterfield, M. D., Federwisch, M., Wollmer, A., Blundell, T. L., & McDonald, N. Q. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08596.x · Cited by 169 · see citing works

A Deletion Mutation within the Ligand Binding Domain Is Responsible for Activation of Epidermal Growth Factor Receptor Gene in Human Brain Tumors

Yamazaki, H., Ohba, Y., Tamaoki, N., et al. (1990) · Japanese Journal of Cancer Research · doi:10.1111/j.1349-7006.1990.tb02644.x · Cited by 159 · see citing works

Selective amplification of the cytoplasmic domain of the epidermal growth factor receptor gene in glioblastoma multiforme.

Malden, L. T., Novak, U., Kaye, A. H., et al. (1988) · PubMed · Cited by 158 · see citing works

Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro

Gilmore, T. D., DeClue, J. E., & Martin, G. S. (1985) · Cell · doi:10.1016/0092-8674(85)90209-0 · Cited by 154 · see citing works

mRNA phenotyping by enzymatic amplification of randomly primed cDNA

Noonan, K. E., & Roninson, I. B. (1988) · Nucleic Acids Research · doi:10.1093/nar/16.21.10366 · Cited by 142 · see citing works

Deletion mapping in human renal cell carcinoma.

Bergerheim, U. S. R., Nordenskjöld, M., & Collins, V. P. (1989) · PubMed · Cited by 133 · see citing works

Relationship between gene amplification and chromosomal deviations in malignant human gliomas

Bigner, S. H., Wong, A. J., Mark, J., et al. (1987) · Cancer Genetics and Cytogenetics · doi:10.1016/0165-4608(87)90045-8 · Cited by 131 · see citing works

Localization of a Major Receptor-Binding Domain for Epidermal Growth Factor by Affinity Labeling

Lax, I., Burgess, W. H., Bellot, F., Ullrich, A., Schlessinger, J., & Givol, D. (1988) · Molecular and Cellular Biology · doi:10.1128/mcb.8.4.1831 · Cited by 121 · see citing works

Expression of an altered epidermal growth factor receptor by human glioblastoma cells.

Steck, P. A., Lee, P., Hung, M., et al. (1988) · PubMed · Cited by 66 · see citing works

Amplification of the Structurally and Functionally Altered Epidermal Growth Factor Receptor Gene (c-erbB) in Human Brain Tumors

Yamazaki, H., Fukui, Y., Ueyama, Y., et al. (1988) · Molecular and Cellular Biology · doi:10.1128/mcb.8.4.1816-1820.1988 · Cited by 55 · see citing works

Analysis of mammalian fibroblast transformation by normal and mutated human EGF receptors.

Jd, H., Hsuan, J. J., & Waterfield, M. D. (1989) · PubMed · Cited by 53 · see citing works

Human epidermal growth factor receptor residue covalently cross-linked to epidermal growth factor.

Wu, D. G., Wang, L. H., Chi, Y., et al. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.8.3151 · Cited by 43 · see citing works

Epidermal growth factor receptor: Mechanisms of activation and signalling

Jorissen, R. (2003) · Experimental Cell Research · doi:10.1016/s0014-4827(02)00098-8 · Cited by 1,565 · see citing works

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors

Mellinghoff, I. K., Wang, M. Y., Vivanco, I., Haas-Kogan, D. A., Zhu, S., Dia, E. Q., Lu, K. V., Yoshimoto, K., Huang, J. H. Y., Chute, D. J., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa051918 · Cited by 1,442 · see citing works

ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics

Arteaga, C. L., & Engelman, J. A. (2014) · Cancer Cell · doi:10.1016/j.ccr.2014.02.025 · Cited by 1,048 · see citing works

EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance

Uribe, M. L., Marrocco, I., & Yarden, Y. (2021) · Cancers · doi:10.3390/cancers13112748 · Cited by 604 · see citing works

Epidermal growth factor receptor targeting in cancer: a review of trends and strategies

Yewale, C., Baradia, D., Vhora, I., Patil, S., & Misra, A. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.07.100 · Cited by 533 · see citing works

Genetic pathways to glioblastomas

Ohgaki, H. (2005) · Neuropathology · doi:10.1111/j.1440-1789.2004.00600.x · Cited by 235 · see citing works

Molecular cloning and tissue distribution of a short form chicken leptin receptor mRNA

Liu, X., Dunn, I., Sharp, P. J., et al. (2006) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2006.02.001 · Cited by 55 · see citing works

Neuron-specific splicing

Hakim, N. H. A., Majlis, B. Y., Suzuki, H., & Tsukahara, T. (2016) · BioScience Trends · doi:10.5582/bst.2016.01169 · Cited by 18 · see citing works

Integrity of the exon 6 sequence is essential for tissue-specific alternative splicing of human leukocyte common antigen pre-mRNA.

Tsai, A. Y., Streuli, M., & Saito, H. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.10.4550 · Cited by 12 · see citing works

Integrity of the Exon 6 Sequence Is Essential for Tissue-Specific Alternative Splicing of Human Leukocyte Common Antigen Pre-mRNA

Tsai, A. Y., Streuli, M., & Saito, H. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.10.4550-4555.1989 · Cited by 34 · see citing works

Structure and alternative splicing of the Presenilin-2 gene

Prihar, G., Fuldner, R., Pérez‐Tur, J., Lincoln, S., Duff, K., Crook, R., Hardy, J., Philips, C. A., Venter, C. J., Talbot, C. J., et al. (1996) · Neuroreport · doi:10.1097/00001756-199607080-00031 · Cited by 47 · see citing works