The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
A close relative of the nuclear, chromosomal high-mobility group protein HMG1 in yeast mitochondria.
Open accessAbstract
ABF2 (ARS-binding factor 2), a small, basic DNA-binding protein that binds specifically to the autonomously replicating sequence ARS1, is located primarily in the mitochondria of the yeast Saccharomyces cerevisiae. The abundance of ABF2 and the phenotype of abf2- null mutants argue that this protein plays a key role in the structure, maintenance, and expression of the yeast mitochondrial genome. The predicted amino acid sequence of ABF2 is closely related to the high-mobility group proteins HMG1 and HMG2 from vertebrate cell nuclei and to several other DNA-binding proteins. Additionally, ABF2 and the other HMG-related proteins are related to a globular domain from the heat shock protein hsp70 family. ABF2 interacts with DNA both nonspecifically and in a specific manner within regulatory regions, suggesting a mechanism whereby it may aid in compacting the mitochondrial genome without interfering with expression.
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Metadata
- Authors
- Diffley, J. F., & Stillman, B.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1991-09
- Volume
- 88
- Issue
- 17
- Pages
- 7864-7868
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2007153791
- Cited by
- 324
- References
- 26
- FWCI
- 6.85
- Type
- journal article
- Language
- en
- Open access
- green
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- Diffley, J. F., & Stillman, B. (1991). A close relative of the nuclear, chromosomal high-mobility group protein HMG1 in yeast mitochondria. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.88.17.7864
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.