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Structure and expression of the hairless gene of mice.

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Cachon-Gonzalez, M B, Fenner, S, Coffin, J M, Moran, C, Best, S, Stoye, J P·1994·Proceedings of the National Academy of Sciences

Abstract

The hairless mutation of mice was caused by insertion of a murine leukemia virus. Starting with sequences flanking the provirus, a series of overlapping clones surrounding the viral integration site were obtained. By using a combination of sequencing, PCR, and exon-trapping techniques, the hairless gene was identified. It encodes a predicted protein of 1182 amino acids, including a potential zinc-finger domain. The expression patterns of the gene closely reflect the phenotype of animals carrying the hairless mutation.

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Metadata

Authors
Cachon-Gonzalez, M. B., Fenner, S., Coffin, J. M., Moran, C., Best, S., & Stoye, J. P.
Venue
Proceedings of the National Academy of Sciences
Published
1994-08-02
Volume
91
Issue
16
Pages
7717-7721
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W1988929732
Cited by
179
References
0
FWCI
7.30
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Structure and expression of the hairless gene of mice. https://app.cochat.ai/papers/10.1073/pnas.91.16.7717
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Cachon-Gonzalez, M. B., Fenner, S., Coffin, J. M., Moran, C., Best, S., & Stoye, J. P. (1994). Structure and expression of the hairless gene of mice. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.91.16.7717

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.