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Chromosomal localization of the callipyge gene in sheep (Ovis aries) using bovine DNA markers.
Open accessAbstract
A mutation causing muscular hypertrophy, with associated leanness and improved feed efficiency, has been recently identified in domestic sheep (Ovis aries). Preliminary results indicate that an autosomal dominant gene may be responsible for this economically advantageous trait. We have exploited the conservation in sequence and chromosomal location of DNA markers across Bovidae to map the corresponding callipyge locus to ovine chromosome 18 using a battery of bovine chromosome 21 markers. Chromosomal localization of the ovine callipyge locus is the first step toward positional cloning of the corresponding gene.
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Citations
Cited by
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Andersson, L. (2001) · Nature Reviews Genetics · doi:10.1038/35052563 · Cited by 425
Koohmaraie, M., Shackelford, S. D., Wheeler, T. L., Lonergan, S. M., & Doumit, M. E. (1995) · Journal of Animal Science · doi:10.2527/1995.73123596x · Cited by 309
Technologies for the control of fat and lean deposition in livestock
Sillence, M. N. (2004) · The Veterinary Journal · doi:10.1016/j.tvjl.2003.10.020 · Cited by 142
Genetics of the phenotypic evolution in sheep: a molecular look at diversity-driving genes
Kalds, P., Zhou, S., Gao, Y., Cai, B., Huang, S., Chen, Y., & Wang, X. (2022) · Genetics Selection Evolution · doi:10.1186/s12711-022-00753-3 · Cited by 85
Determination and regulation of body composition in elite athletes
Sonksen, P. (2018) · British Journal of Sports Medicine · doi:10.1136/bjsports-2016-096742 · Cited by 23
Metadata
- Authors
- Cockett, N. E., Jackson, S. P., Shay, T. L., Nielsen, D., Moore, S. S., Steele, M. R., Barendse, W., Green, R. D., & Georges, M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1994-04-12
- Volume
- 91
- Issue
- 8
- Pages
- 3019-3023
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2079859027
- Cited by
- 203
- References
- 0
- FWCI
- 6.94
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Chromosomal localization of the callipyge gene in sheep (Ovis aries) using bovine DNA markers. https://app.cochat.ai/papers/10.1073/pnas.91.8.3019
- The paper
- Cockett, N. E., Jackson, S. P., Shay, T. L., Nielsen, D., Moore, S. S., Steele, M. R., Barendse, W., Green, R. D., & Georges, M. (1994). Chromosomal localization of the callipyge gene in sheep (Ovis aries) using bovine DNA markers. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.91.8.3019
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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