A role for Rho in Ras transformation

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The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

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The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

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Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

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Activation of Raf as a Result of Recruitment to the Plasma Membrane

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An essential role for Rac in Ras transformation

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Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

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The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

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Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

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A role for Rac in Tiaml-induced membrane ruffling and invasion

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Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction.

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Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product

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Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).

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The Ras signal transduction pathway

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Cooperative interaction of S. pombe proteins required for mating and morphogenesis

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Activation of rat liver phospholipase D by the small GTP-binding protein RhoA

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Lysophosphatidic acid signalling

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Relationship Among Guanine Nucleotide Exchange, GTP Hydrolysis, and Transforming Potential of Mutated ras Proteins

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ADP-ribosylation of rho p21 inhibits lysophosphatidic acid-induced protein tyrosine phosphorylation and phosphatidylinositol 3-kinase activation in cultured Swiss 3T3 cells.

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Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein Rho.

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Rac mediates growth factor-induced arachidonic acid release

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A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways.

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Expression of transduced tropomyosin 1 cDNA suppresses neoplastic growth of cells transformed by the ras oncogene.

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Suppression of tumorigenicity in simian virus 40-transformed 3T3 cells transfected with alpha-actinin cDNA.

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Direct Involvement of the Small GTP-binding Protein Rho in lbc Oncogene Function

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Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras.

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The role of p21ras in receptor tyrosine kinase signalling

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Characterization and expression of the human rhoH12 gene product.

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Tumorigenic activity of rho genes from Aplysia californica.

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Different structural organization of Ras and Rho effector domains.

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Cytoskeletal reorganization in NIH 3T3 fibroblasts expressing the ras oncogene.

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Dbl and Vav Mediate Transformation via Mitogen-Activated Protein Kinase Pathways That are Distinct from Those Activated by Oncogenic Ras

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Oncogenic Activation of Ras Proteins

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Characterization and Expression of the Human rhoH12 Gene Product

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p21 in cancer: Intricate networks and multiple activities

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Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways

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The Ras-related Protein Rheb Is Farnesylated and Antagonizes Ras Signaling and Transformation

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Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy

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Oncogenic Ras leads to Rho activation by activating the mitogen-activated protein kinase pathway and decreasing Rho-GTPase-activating protein activity

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R-Ras3, a brain-specific Ras-related protein, activates Akt and promotes cell survival in PC12 cells

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Communication between the extracellular environment, cytoplasmic signalling cascades and the nuclear cell-cycle machinery

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Paracingulin Regulates the Activity of Rac1 and RhoA GTPases by Recruiting Tiam1 and GEF-H1 to Epithelial Junctions

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MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assembly

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In silico screening of Rac1 ligand specificity

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Regulation of fibronectin matrix assembly and capillary morphogenesis in endothelial cells by Rho family GTPases

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