The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
In vitro binding of type 1-fimbriated Escherichia coli to uroplakins Ia and Ib: relation to urinary tract infections.
Open accessAbstract
Urinary tract infections, caused mainly by Escherichia coli, are among the most common infectious diseases. Most isolates of the uropathogenic E.coli can express type 1 and P fimbriae containing adhesins that recognize cell receptors. While P fimbriae recognize kidney glycolipid receptors and are involved in peyelonephritis, the urothelial for type 1 fimbriae were not identified. We show that type 1-fimbriated E. coli recognize uroplakins Ia and Ib, two major glycoproteins of urothelial apical plaques. Anchorage of E. coli to urothelial surface via type 1 fimbriae-uroplakin I interactions may play a role in its bladder colonization and eventual ascent through the ureters, against urine flow, to invade the kidneys.
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Bäckhed, F., Alsén, B., Roche, N., Ångström, J., von Euler, A., Breimer, M. E., Westerlund-Wikström, B., Teneberg, S., & Richter-Dahlfors, A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111640200 · Cited by 96
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Metadata
- Authors
- Wu, X. R., Sun, T. T., & Medina, J. J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1996-09-03
- Volume
- 93
- Issue
- 18
- Pages
- 9630-9635
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1995025776
- Cited by
- 342
- References
- 25
- FWCI
- 4.55
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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