The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Chromatin components as part of a putative transcriptional repressing complex
Open accessAbstract
The Drosophila HMG1-like protein DSP1 was identified by its ability to inhibit the transcriptional activating function of Dorsal in a promoter-specific fashion in yeast. We show here that DSP1 as well as its mammalian homolog hHMG2 bind to the mammalian protein SP100B and that SP100B in turn binds to human homologs of HP1. The latter is a Drosophila protein that is involved in transcriptional silencing. Each of these proteins represses transcription when tethered to DNA in mammalian cells. These results suggest how heterochromatin proteins might be recruited to specific sites on DNA with resultant specific effects on gene expression.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Conversion of Dorsal from an activator to a repressor by the global corepressor Groucho
Dubnicoff, T., Valentine, S. A., Chen, G., Shi, T., Lengyel, J. A., Paroush, Z., & Courey, A. J. (1997) · Genes & Development · doi:10.1101/gad.11.22.2952 · Cited by 155
Cited by
Hay, R. T. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.03.012 · Cited by 1,622
Kang, R., Chen, R., Zhang, Q., Hou, W., Wu, S., Cao, L., Huang, J., Yu, Y., Fan, X.-G., Yan, Z., et al. (2014) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2014.05.001 · Cited by 956
Bustin, M. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.8.5237 · Cited by 845
Vakoc, C. R., Mandat, S. A., Olenchock, B. A., & Blobel, G. A. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.06.011 · Cited by 696
The transcriptional role of PML and the nuclear body
Zhong, S., Salomoni, P., & Pandolfi, P. P. (2000) · Nature Cell Biology · doi:10.1038/35010583 · Cited by 577
Metadata
- Authors
- Lehming, N., Le Saux, A., Schüller, J., & Ptashne, M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1998-06-23
- Volume
- 95
- Issue
- 13
- Pages
- 7322-7326
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2135002148
- Cited by
- 175
- References
- 1
- FWCI
- 7.88
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Chromatin components as part of a putative transcriptional repressing complex. https://app.cochat.ai/papers/10.1073/pnas.95.13.7322
- The paper
- Lehming, N., Le Saux, A., Schüller, J., & Ptashne, M. (1998). Chromatin components as part of a putative transcriptional repressing complex. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.95.13.7322
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
