The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Genome-wide analysis of developmental and sex-regulated gene expression profiles in Caenorhabditis elegans
Open accessAbstract
We have constructed DNA microarrays containing 17,871 genes, representing about 94% of the 18,967 genes currently annotated in the Caenorhabditis elegans genome. These DNA microarrays can be used as a tool to define a nearly complete molecular profile of gene expression levels associated with different developmental stages, growth conditions, or worm strains. Here, we used these full-genome DNA microarrays to show the relative levels of gene expression for nearly every gene during development, from eggs through adulthood. These expression data can help reveal when a gene may act during development. We also compared gene expression in males to that of hermaphrodites and found a total of 2,171 sex-regulated genes ( P < 0.05). The sex-regulated genes provide a global view of the differences between the sexes at a molecular level and identify many genes likely to be involved in sex-specific differentiation and behavior.
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Cites
Cluster analysis and display of genome-wide expression patterns
Eisen, M. B., Spellman, P. T., Brown, P. O., & Botstein, D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14863 · Cited by 16,184
The embryonic cell lineage of the nematode Caenorhabditis elegans
Sulston, J. E., Schierenberg, E., White, J. G., & Thomson, J. N. (1983) · Developmental Biology · doi:10.1016/0012-1606(83)90201-4 · Cited by 4,199
A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans
Barr, M. M., & Sternberg, P. W. (1999) · Nature · doi:10.1038/43913 · Cited by 541
Cited by
p38 MAPK Regulates Expression of Immune Response Genes and Contributes to Longevity in C. elegans
Troemel, E. R., Chu, S. W., Reinke, V., Lee, S. S., Ausubel, F. M., & Kim, D. H. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020183 · Cited by 678
Self-citationMcCarroll, S. A., Murphy, C. T., Zou, S., Pletcher, S. D., Chin, C.-S., Jan, Y. N., Kenyon, C., Bargmann, C. I., & Li, H. (2004) · Nature Genetics · doi:10.1038/ng1291 · Cited by 454
Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF‐16
McElwee, J., Bubb, K., & Thomas, J. H. (2003) · Aging Cell · doi:10.1046/j.1474-9728.2003.00043.x · Cited by 416
Lee, I., Lehner, B., Crombie, C., Wong, W., Fraser, A. G., & Marcotte, E. M. (2008) · Nature Genetics · doi:10.1038/ng.2007.70 · Cited by 281
Sexual dimorphism in mammalian gene expression
Rinn, J. L., & Snyder, M. (2005) · Trends in Genetics · doi:10.1016/j.tig.2005.03.005 · Cited by 286
Metadata
- Authors
- Jiang, M., Ryu, J., Kiraly, M., Duke, K., Reinke, V., & Kim, S. K.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2000-12-26
- Volume
- 98
- Issue
- 1
- Pages
- 218-223
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2032422419
- Cited by
- 285
- References
- 3
- FWCI
- 9.12
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Jiang, M., Ryu, J., Kiraly, M., Duke, K., Reinke, V., & Kim, S. K. (2001). Genome-wide analysis of developmental and sex-regulated gene expression profiles in Caenorhabditis elegans. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.98.1.218
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