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Cited by 165

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Differential adsorption of nucleic acid bases: Relevance to the origin of life

Open access
Sowerby, Stephen J., Cohn, Corey A., Heckl, Wolfgang M., Holm, Nils G.·2001·Proceedings of the National Academy of Sciences

Abstract

The adsorption of organic molecules onto the surfaces of inorganic solids has long been considered a process relevant to the origin of life. We have determined the equilibrium adsorption isotherms for the nucleic acid purine and pyrimidine bases dissolved in water on the surface of crystalline graphite. The markedly different adsorption behavior of the bases describes an elutropic series: guanine > adenine > hypoxanthine > thymine > cytosine > uracil. We propose that such differential properties were relevant to the prebiotic chemistry of the bases and may have influenced the composition of the primordial genetic architecture.

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Crossref · 10.1073/pnas.98.3.820

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Metadata

Authors
Sowerby, S. J., Cohn, C. A., Heckl, W. M., & Holm, N. G.
Venue
Proceedings of the National Academy of Sciences
Published
2001-01-30
Volume
98
Issue
3
Pages
820-822
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W1964637595
Cited by
165
References
6
FWCI
4.48
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Differential adsorption of nucleic acid bases: Relevance to the origin of life. https://app.cochat.ai/papers/10.1073/pnas.98.3.820
The paper
Sowerby, S. J., Cohn, C. A., Heckl, W. M., & Holm, N. G. (2001). Differential adsorption of nucleic acid bases: Relevance to the origin of life. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.98.3.820

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.