ADP-ribosylation Factor Functions Synergistically with a 50-kDa Cytosolic Factor in Cell-free Activation of Human Neutrophil Phospholipase D
Open accessAbstract
Proteins in both the cytosol and plasma membrane are needed to reconstitute cell-free phospholipase D activity from phagocytes (Olson, S., Bowman, E. P., and Lambeth, J. D. (1991) J. Biol. Chem. 266, 17236-17242); membrane factors include a small GTP-binding protein in the Rho family (Bowman, E., Uhlinger, D. J., and Lambeth, J. D. (1993) J. Biol. Chem. 268, 21509-21512). ADP-ribosylation factor (ARF) was recently implicated as the cytosolic factor, as it activates phospholipase D in HL-60 membranes. Herein, we show that ion exchange chromatography separates ARF from the major phospholipase D-stimulating cytosolic factor. Both bovine brain ARF and recombinant human ARF-1 stimulated a small amount of phospholipase D activity in the absence of cytosol (about 10% of the response seen with cytosol). With a high concentration of ARF-depleted cytosol, ARF did not further activate. However, at low cytosol, ARF caused marked activation. Thus, ARF synergizes with the cytosolic factor in phospholipase D activation.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Heme-transport proteins have recently been identified in several different cell types.
“Heme-transport proteins have recently been identified in several different cell types [reviewed in (174)].”
From Intracellular iron transport and storage: from molecular mechanisms to health implications (2008) · cites this paper as [174]
Cites
Current protocols in molecular biology
Dudley, R. K. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80264-3 · Cited by 6,037 · see citing works
Brown, H. A., Gutowski, S., Moomaw, C. R., Slaughter, C. A., & Sternwels, P. C. (1993) · Cell · doi:10.1016/0092-8674(93)90323-i · Cited by 901 · see citing works
Phospholipase D: a Downstream Effector of ARF in Granulocytes
Cockcroft, S., Thomas, G. M. H., Fensome, A. C., Geny, B., Cunningham, E., Gout, I. T., Hiles, I. D., Totty, N. F., Truong, O., & Hsuan, J. J. (1994) · Science · doi:10.1126/science.8290961 · Cited by 631 · see citing works
Growth factor-like action of phosphatidic acid
Moolenaar, W. H., Kruijer, W., Tilly, B. C., Verlaan-Klink, I., Bierman, A. J., & de Laat, S. W. (1986) · Nature · doi:10.1038/323171a0 · Cited by 513 · see citing works
Involvement of GTP-binding “G” proteins in transport through the Golgi stack
Melançon, P., Glick, B. S., Malhotra, V., Weidman, P. J., Serafini, T. A., Gleason, M. L., Orci, L., & Rothman, J. E. (1987) · Cell · doi:10.1016/0092-8674(87)90591-5 · Cited by 501 · see citing works
Billah, M. M., Eckel, S., Mullmann, T. J., Egan, R. W., & Siegel, M. I. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71460-9 · Cited by 424 · see citing works
Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles.
Tanigawa, G., Orci, L., AMHERDT, M., Ravazzola, M., Helms, J. B., & Rothman, J. E. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.123.6.1365 · Cited by 279 · see citing works
Activation of rat liver phospholipase D by the small GTP-binding protein RhoA
Malcolm, K. C., Ross, A. H., Qiu, R., Symons, M. H., & Exton, J. H. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47140-2 · Cited by 258 · see citing works
Conricode, K. M., Brewer, K., & Exton, J. H. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42502-1 · Cited by 239 · see citing works
Schmid, P. C., Reddy, P. V., Natarajan, V., & Schmid, H. H. O. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44667-9 · Cited by 232 · see citing works
Bowman, E. P., Uhlinger, D. J., & Lambeth, J. D. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)80570-5 · Cited by 229 · see citing works
Self-citationRandazzo, P. A., & Kahn, R. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34124-8 · Cited by 199 · see citing works
Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex
Matteis, M. A. D., Santini, G., Kahn, R., Tullio, G. D., & Luini, A. (1993) · Nature · doi:10.1038/364818a0 · Cited by 158 · see citing works
Tsai, S. C., Noda, M., Adamik, R., Chang, P. P., Chen, H. C., Moss, J., & Vaughan, M. J. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)77942-3 · Cited by 141 · see citing works
Isolation of human eosinophil phospholipase D.
Kater, L. A., Goetzl, E. J., & Austen, K. F. (1976) · Journal of Clinical Investigation · doi:10.1172/jci108385 · Cited by 139 · see citing works
Olson, S. C., Bowman, E. P., & Lambeth, J. D. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)47364-x · Cited by 138 · see citing works
Self-citationStimulation of phosphatidic acid of calcium influx and cyclic GMP synthesis in neuroblastoma cells.
Ohsako, S., & Deguchi, T. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)68537-6 · Cited by 132 · see citing works
Ca2 +‐mobilizing hormones elicit phosphatidylethanol accumulation via phospholipase D activation
Bocckino, S. B., Wilson, P. B., & Exton, J. H. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)81157-2 · Cited by 129 · see citing works
Phosphatidohydrolase activity in a solubilized preparation from rat brain particulate fraction
Saito, M., & Kanfer, J. N. (1975) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(75)90346-x · Cited by 110 · see citing works
An activating mutation in ARF1 stabilizes coatomer binding to Golgi membranes.
Teal, S. B., Hsu, V. W., Peters, P. J., Klausner, R. D., & Donaldson, J. G. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)41837-0 · Cited by 107 · see citing works
Tsai, S. C., Noda, M., Adamik, R., Moss, J., & Vaughan, M. J. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.15.5139 · Cited by 106 · see citing works
Perry, D. K., Hand, W. L., Edmondson, D. E., & Lambeth, J. D. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.149.8.2749 · Cited by 102 · see citing works
Self-citationAnthes, J. C., Eckel, S., Siegel, M. I., Egan, R. W., & Billah, M. M. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(89)92187-6 · Cited by 90 · see citing works
Second messenger function of phosphatidic acid in platelet activation
Kroll, M. H., Zavoico, G. B., & Schafer, A. I. (1989) · Journal of Cellular Physiology · doi:10.1002/jcp.1041390315 · Cited by 84 · see citing works
Granulocyte phospholipase D is activated by a guanine nucleotide dependent protein factor
Anthes, J. C., Wang, P., Siegel, M. I., Egan, R. W., & Billah, M. M. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(05)81225-2 · Cited by 62 · see citing works
Biochemical characterization of phospholipase D activity from human neutrophils
Balsinde, J., Dı́ez, E., FERNANDEZ, B., & Mollinedo, F. (1989) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1989.tb15265.x · Cited by 55 · see citing works
Sphingolipids inhibit insulin and phorbol ester stimulated uptake of 2-deoxyglucose
Nelson, D. H., & Murray, D. K. (1986) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(86)90303-7 · Cited by 50 · see citing works
Mitogenic Action of Lysophosphatidic Acid
Moolenaar, W. H. (1991) · Advances in cancer research · doi:10.1016/s0065-230x(08)60996-3 · Cited by 49 · see citing works
[20] Quantitation and purification of ADP-ribosylation factor
Kahn, R. (1991) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(91)95169-k · Cited by 29 · see citing works
Noda, M., Tsai, S. C., Adamik, R., Bobak, D. A., Moss, J., & Vaughan, M. M. (1989) · Biochemistry · doi:10.1021/bi00445a057 · Cited by 19 · see citing works
Bradykinin and Phorbol Dibutyrate Activate Phospholipase D in PC12 Cells by Different Mechanisms
Horwitz, J., & Ricanati, S. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb08463.x · Cited by 14 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Activators and Target Genes of Rel/NF-кB Transcription Factors
Loop, T., & Pahl, H. L. (2003) · Springer eBooks · doi:10.1007/978-94-010-0163-2_1 · Cited by 3,179 · see citing works
Signal Transduction through MAP Kinase Cascades
Lewis, T. S., Shapiro, P. S., & Ahn, N. G. (1998) · Advances in cancer research · doi:10.1016/s0065-230x(08)60765-4 · Cited by 1,746 · see citing works
Highly elevated ferritin levels and the diagnosis of hemophagocytic lymphohistiocytosis
Allen, C. E., Yu, X., Kozinetz, C. A., & McClain, K. L. (2007) · Pediatric Blood & Cancer · doi:10.1002/pbc.21423 · Cited by 637 · see citing works
Intracellular iron transport and storage: from molecular mechanisms to health implications
Mackenzie, E. L., Iwasaki, K., & Tsuji, Y. (2008) · Antioxidants & Redox Signaling · doi:10.1089/ars.2007.1893 · Cited by 526 · see citing works
Phospholipase D: a lipid centric review
Jenkins, G. M., & Frohman, M. A. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5195-z · Cited by 510 · see citing works
Regulation of iron acquisition and storage: consequences for iron-linked disorders
De Domenico, I., McVey Ward, D., & Kaplan, J. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2295 · Cited by 464 · see citing works
Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D.
Singer, W., Brown, H., & Sternweis, P. (1997) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.66.1.475 · Cited by 402 · see citing works
Exton, J. H. (1999) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(99)00089-x · Cited by 366 · see citing works
MAP kinase pathways activated by stress: The p38 MAPK pathway
Obata, T., Brown, G. E., & Yaffe, M. B. (2000) · Critical Care Medicine · doi:10.1097/00003246-200004001-00008 · Cited by 355 · see citing works
McDermott, M. I., Wakelam, M. J. O., & Morris, A. J. (2004) · Biochemistry and Cell Biology · doi:10.1139/o03-079 · Cited by 333 · see citing works
New Developments in Phospholipase D
Exton, J. H. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.25.15579 · Cited by 307 · see citing works
Involvement of Ral GTPase in v-Src-induced phospholipase D activation
Jiang, H., Luo, J.-Q., Urano, T., Frankel, P., Lu, Z., Foster, D. A., & Feig, L. A. (1995) · Nature · doi:10.1038/378409a0 · Cited by 265 · see citing works
Singer, W. D., Brown, H. A., Jiang, X., & Sternweis, P. C. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.8.4504 · Cited by 254 · see citing works
Cloning and Initial Characterization of a Human Phospholipase D2 (hPLD2)
López, I., Arnold, R. S., & Lambeth, J. D. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.21.12846 · Cited by 236 · see citing works
Self-citationTargeting phospholipase D in cancer, infection and neurodegenerative disorders
Brown, H. A., Thomas, P. G., & Lindsley, C. W. (2017) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2016.252 · Cited by 209 · see citing works
Messenger functions of phosphatidic acid
English, D. K., Cui, Y., & Siddiqui, R. A. (1996) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(96)02549-2 · Cited by 179 · see citing works
Crystal structure of RhoA–GDP and its functional implications
Wei, Y., Zhang, Y., Derewenda, U., Liu, X., Minor, W., Nakamoto, R. K., Somlyo, A. V., Somlyo, A. P., & Derewenda, Z. S. (1997) · Nature Structural Biology · doi:10.1038/nsb0997-699 · Cited by 177 · see citing works
Feelders, Vreugdenhil, Eggermont, Kuiper‐Kramer, Eijk, V., & Swaak (1998) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.1998.00323.x · Cited by 172 · see citing works
Multiple intracellular MAP kinase signaling cascades
Bokemeyer, D., Sorokin, A., & Dunn, M. J. (1996) · Kidney International · doi:10.1038/ki.1996.172 · Cited by 173 · see citing works
Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms
Hevroni, D., Rattner, A., Bundman, M., Lederfein, D., Gabarah, A., Mangelus, M., Silverman, M. A., Kedar, H., Naor, C., Kornuc, M., et al. (1998) · Journal of Molecular Neuroscience · doi:10.1007/bf02737120 · Cited by 95 · see citing works
Smith, G. H., & Chepko, G. (2001) · Microscopy Research and Technique · doi:10.1002/1097-0029(20010115)52:2 · Cited by 173 · see citing works
Exton, J. H. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.t01-1-00010.x · Cited by 157 · see citing works
Coupling Heme and Iron Metabolism <i>via</i> Ferritin H Chain
Gozzelino, R., & Soares, M. P. (2014) · Antioxidants & Redox Signaling · doi:10.1089/ars.2013.5666 · Cited by 151 · see citing works
Evidence for Rho-mediated Agonist Stimulation of Phospholipase D in Rat1 Fibroblasts
Malcolm, K. C., Elliott, C. M., & Exton, J. H. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.22.13135 · Cited by 149 · see citing works
Cloning and Characterization of Phospholipase D from Rat Brain
Park, S., Provost, J. J., Bae, C. D., Ho, W., & Exton, J. H. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.46.29263 · Cited by 138 · see citing works
Resolved Phospholipase D Activity Is Modulated by Cytosolic Factors Other than Arf
Singer, W. D., Brown, H. A., Bokoch, G., & Sternweis, P. C. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.25.14944 · Cited by 130 · see citing works
Regulation of Phospholipase D by Protein Kinase C in Human Neutrophils
López, I., Burns, D. J., & Lambeth, J. D. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.33.19465 · Cited by 123 · see citing works
Self-citationPark, J. B., Kim, J. H., Kim, Y. D., Ha, S. H., Kim, J. H., Yoo, J.-S., Du, G., Frohman, M. A., Suh, P., & Ryu, S. H. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002463200 · Cited by 122 · see citing works
Regulation of Membrane-bound Phospholipase D by Protein Kinase C in HL60 Cells
Ohguchi, K., Banno, Y., Nakashima, S., & Nozawa, Y. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.8.4366 · Cited by 120 · see citing works
Activation of phospholipase D1 by direct interaction with ADP‐ribosylation factor 1 and RalA
Kim, J. H., Lee, S. D., Han, J. M., Lee, T. G., Kim, Y. D., Park, J. B., Lambeth, J. D., Suh, P., & Ryu, S. H. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00661-9 · Cited by 115 · see citing works
Self-citationActin Directly Interacts with Phospholipase D, Inhibiting Its Activity
Lee, S., Park, J. B., Kim, J. H., Kim, Y. D., Kim, J. H., Shin, K.-J., Lee, J. S., Ha, S. H., Suh, P., & Ryu, S. H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008521200 · Cited by 111 · see citing works
Abousalham, A., Liossis, C., O'Brien, L., & Brindley, D. N. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.2.1069 · Cited by 107 · see citing works
Exton, J. H. (1998) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s0005-2760(98)00124-6 · Cited by 107 · see citing works
Structure and function of the low Mr phosphotyrosine protein phosphatases
Ramponi, G., & Stefani, M. (1997) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/s0167-4838(97)00087-3 · Cited by 105 · see citing works
Kuribara, H., Kenji, T., Yokozeki, T., Sasaki, T., Takai, Y., Morii, N., Narumiya, S., Katada, T., & Kanaho, Y. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.43.25667 · Cited by 103 · see citing works
Houle, M. G., Kahn, R., Naccache, P. H., & Bourgoin, S. G. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.39.22795 · Cited by 95 · see citing works
Fensome, A. C., Whatmore, J. L., Morgan, C. P., Jones, D. H., & Cockcroft, S. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.21.13157 · Cited by 94 · see citing works
Microarray Analysis of Eosinophils Reveals a Number of Candidate Survival and Apoptosis Genes
Temple, R., Allen, E., Fordham, J., Phipps, S., Schneider, H.-C., Lindauer, K., Hayes, I., Lockey, J., Pollock, K., & Jupp, R. A. (2001) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.25.4.4456 · Cited by 81 · see citing works
Provost, J. J., FUDGE, J., ISRAELIT, S., Siddiqi, A. R., & Exton, J. H. (1996) · Biochemical Journal · doi:10.1042/bj3190285 · Cited by 81 · see citing works
Regulation of phospholipase D by protein kinase C
Kiss, Z. (1996) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(96)02547-9 · Cited by 74 · see citing works
Kwak, J.-Y., López, I., Uhlinger, D. J., Ryu, S. H., & Lambeth, J. D. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.45.27093 · Cited by 70 · see citing works
Self-citationRegulation of phospholipase D by tyrosine kinases
Natarajan, V., Scribner, W. M., & Vepa, S. (1996) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(96)02548-0 · Cited by 64 · see citing works
Phospholipase D Regulation by a Physical Interaction with the Actin-Binding Protein Gelsolin
Steed, P. M., Nagar, S., & Wennogle, L. P. (1996) · Biochemistry · doi:10.1021/bi952370j · Cited by 64 · see citing works
Biochemistry and cell biology of phospholipase D in human neutrophils
Olson, S. C., & Lambeth, J. D. (1996) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(96)02541-8 · Cited by 60 · see citing works
Self-citationLow-molecular-weight GTP-binding proteins and leukocyte signal transduction
Quinn, M. T. (1995) · Journal of Leukocyte Biology · doi:10.1002/jlb.58.3.263 · Cited by 59 · see citing works
Qian, F., Zhen, F., Ong, C., Jin, S., Soo, H. M., Stainier, D. Y. R., Lin, S., Peng, J., & Wen, Z. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20444 · Cited by 57 · see citing works
Phospholipase D: Regulation by GTPases and protein kinase C and physiological relevance
Cockcroft, S. (1996) · Progress in Lipid Research · doi:10.1016/s0163-7827(96)00009-4 · Cited by 56 · see citing works
Lipase Activities of p37, the Major Envelope Protein of Vaccinia Virus
Baek, S., Kwak, J.-Y., Lee, S. H., Lee, T., Ryu, S. H., Uhlinger, D. J., & Lambeth, J. D. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.51.32042 · Cited by 55 · see citing works
Self-citationSignaling mechanisms in infantile hemangioma
Boye, E., & Olsen, B. R. (2009) · Current Opinion in Hematology · doi:10.1097/moh.0b013e32832a07ff · Cited by 53 · see citing works
Gene expression changes following extinction testing in a heroin behavioral incubation model
Kuntz-Melcavage, K. L., Brucklacher, R. M., Grigson, P. S., Freeman, W. M., & Vrana, K. E. (2009) · BMC Neuroscience · doi:10.1186/1471-2202-10-95 · Cited by 53 · see citing works
Organization of the Ferritin Genes in Drosophila melanogaster
Dunkov, B. C., & Georgieva, T. G. (1999) · DNA and Cell Biology · doi:10.1089/104454999314791 · Cited by 49 · see citing works
CtBP1/BARS is an activator of phospholipase D1 necessary for agonist‐induced macropinocytosis
Haga, Y., Miwa, N., Jahangeer, S. M., Okada, T., & Nakamura, S. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.78 · Cited by 48 · see citing works
Structure and regulation of human phospholipase D
Bowling, F. Z., Frohman, M. A., & Airola, M. V. (2021) · Advances in Biological Regulation · doi:10.1016/j.jbior.2020.100783 · Cited by 46 · see citing works
Pietrangelo, A. (2002) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-0593-8_2 · Cited by 43 · see citing works
Dumaz, N., Duthu, A., Ehrhart, J., Drougard, C., Appella, E., Anderson, C. W., May, P., Sarasin, A. R., & Daya–Grosjean, L. (1997) · Molecular Carcinogenesis · doi:10.1002/(sici)1098-2744(199712)20:4 · Cited by 66 · see citing works
Schmidt, M., Rümenapp, U., Nehls, C., Ott, S., Keller, J., von Eichel‐Streiber, C., & Jakobs, K. H. (1996) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1996.0707h.x · Cited by 40 · see citing works
Azotemia, TNFα, and LPS prime the human neutrophil oxidative burst by distinct mechanisms
McLeish, K. R., Klein, J. B., Lederer, E. D., Head, K. Z., & Ward, R. A. (1996) · Kidney International · doi:10.1038/ki.1996.330 · Cited by 34 · see citing works
Enzymology of mammalian phospholipases D: in vitro studies
Liscovitch, M., & Caspi, V. C. (1996) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(96)02544-3 · Cited by 33 · see citing works
FYVE-DSP1, a Dual-Specificity Protein Phosphatase Containing an FYVE Domain
Zhao, R., Qi, Y., & Zhao, Z. J. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.2417 · Cited by 29 · see citing works
Inhibition of Phospholipase D by a Protein Factor from Bovine Brain Cytosol
Kim, J. H., Suh, Y. J., Lee, T. G., Kim, Y. D., Bae, S. S., Kim, M. J., Lambeth, J. D., Suh, P. G., & Ryu, S. H. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.41.25213 · Cited by 28 · see citing works
Self-citationAnti‐apoptotic role of phospholipase D in spontaneous and delayed apoptosis of human neutrophils
Park, M.-A., Lee, M.-J., Lee, S. H., Jung, D. K., & Kwak, J. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)02705-9 · Cited by 27 · see citing works
Self-citationRole of mitochondria in ultraviolet-induced oxidative stress
Gniadecki, R., Thorn, T., Vičanová, J., Petersen, A., & Wulf, H. C. (2000) · Journal of Cellular Biochemistry · doi:10.1002/1097-4644(20010201)80:2 · Cited by 121 · see citing works
Downregulation of Phospholipase D by Protein Kinase A in a Cell-Free System of Human Neutrophils
Kwak, J., & Uhlinger, D. J. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1941 · Cited by 25 · see citing works
Self-citationBradshaw, C. D., Ella, K. M., Chen, Q., Sansbury, H. M., Wisehart-Johnson, A. E., & Meier, K. E. (1996) · Immunology Letters · doi:10.1016/s0165-2478(96)02614-4 · Cited by 24 · see citing works
Differential ferritin expression is associated with iron deficiency in coeliac disease
Sharma, N., Begum, J., Eksteen, B., Elagib, A., Brookes, M., Cooper, B. T., Tselepis, C., & Iqbal, T. H. (2009) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0b013e328308676b · Cited by 22 · see citing works
Differential Expression and Oxidation of MKP-1 Modulates TNF-α Gene Expression
Tephly, L. A., & Carter, A. B. (2007) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2006-0268oc · Cited by 22 · see citing works
del Peso, L., Lucas, L., Esteve, P., & Lacal, J. C. (1997) · Biochemical Journal · doi:10.1042/bj3220519 · Cited by 22 · see citing works
Phospholipase D development during differentiation of human promyelocytic leukemic HL60 cells
Ohguchi, K., Nakashima, S., & Nozawa, Y. (1999) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(99)00096-7 · Cited by 19 · see citing works
Requirement of G M2 ganglioside activator for phospholipase D activation
Nakamura, S., Akisue, T., Jinnai, H., Hitomi, T., Sarkar, S., Miwa, N., Okada, T., Yoshida, K., Kuroda, S., Kikkawa, U., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.21.12249 · Cited by 19 · see citing works
Acidic phospholipids inhibit the phospholipase D activity of rat brain neuronal nuclei
Kanfer, J. N., McCartney, D. G., Singh, I. N., & Freysz, L. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00205-0 · Cited by 19 · see citing works
Iderstine, S. C. V., Byers, D. M., Ridgway, N. D., & Cook, H. W. (1997) · Journal of Lipid Mediators and Cell Signalling · doi:10.1016/s0929-7855(96)00552-4 · Cited by 18 · see citing works
Naze, S., Stunff, H. L., Dokhac, L., Thomas, G., & Harbon, S. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36585-1 · Cited by 18 · see citing works
Tan, Z., Dohi, S., Ohguchi, K., Nakashima, S., Banno, Y., Ono, Y., & Nozawa, Y. (1999) · Biochemical Pharmacology · doi:10.1016/s0006-2952(99)00283-x · Cited by 18 · see citing works
Arf and RhoA Regulate Both the Cytosolic and the Membrane-bound Phospholipase D from Human Placenta
Vinggaard, A. M., Provost, J. J., Exton, J. H., & Hansen, H. S. (1997) · Cellular Signalling · doi:10.1016/s0898-6568(96)00140-4 · Cited by 17 · see citing works
Regulation of mammalian phospholipase D2: interaction with and stimulation by GM2 activator
Sarkar, S., Miwa, N., KOMINAMI, H., Igarashi, N., Hayashi, S., Okada, T., Jahangeer, S. M., & Nakamura, S. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3590599 · Cited by 16 · see citing works
Prenylation of Ras GTPase Superfamily Proteins and Their Function in Immunobiology
Lobell, R. B. (1998) · Advances in immunology · doi:10.1016/s0065-2776(08)60559-3 · Cited by 15 · see citing works
Houle, M. G., Naccache, P. H., & Bourgoin, S. G. (1999) · Journal of Leukocyte Biology · doi:10.1002/jlb.66.6.1021 · Cited by 15 · see citing works
Shimooku, K., Akisue, T., Jinnai, H., Hitomi, T., Ogino, C., Yoshida, K., Nakamura, S., & Nishizuka, Y. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00483-8 · Cited by 15 · see citing works
The Regulation of MAP Kinase Pathways by MAP Kinase Phosphatases
Kelly, K., & Chu, Y. (2000) · Humana Press eBooks · doi:10.1007/978-1-59259-218-0_10 · Cited by 14 · see citing works
Dubyak, G., & Kertesy, S. B. (1997) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1997.9946 · Cited by 14 · see citing works
Regulation of Neuronal Ferritin Heavy Chain, A New Player in Opiate-Induced Chemokine Dysfunction
Abt, A., & Meucci, O. (2011) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-011-9278-3 · Cited by 13 · see citing works
Role of Sphingolipids in Regulating the Phospholipase D Pathway and Cell Division
Gómez‐Muñoz, A., Abousalham, A., Kikuchi, Y., Waggoner, D. W., & Brindley, D. N. (1997) · Molecular biology intelligence unit · doi:10.1007/978-3-662-22425-0_8 · Cited by 13 · see citing works
Small GTPase-regulated phospholipase D in granulocytes
Houle, M. G., & Bourgoin, S. G. (1996) · Biochemistry and Cell Biology · doi:10.1139/o96-050 · Cited by 12 · see citing works
Effects of the Ferritin Open Reading Frame on Translational Induction by iron
Mascotti, D. P., Goessling, L. S., Rup, D., & Thach, R. E. (1996) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)60191-9 · Cited by 11 · see citing works
Kypreos, K. E., Birk, D. E., Trinkaus‐Randall, V., Hartmann, D. J., & Sonenshein, G. E. (2000) · Journal of Cellular Biochemistry · doi:10.1002/1097-4644(20010101)80:1 · Cited by 34 · see citing works
Russo, J., & Russo, I. H. (2004) · Springer eBooks · doi:10.1007/978-3-642-18736-0_5 · Cited by 9 · see citing works
Price, S. R., Nightingale, M. S., Tsuchiya, M., Moss, J., & Vaughan, M. M. (1996) · Molecular and Cellular Biochemistry · doi:10.1007/bf00226058 · Cited by 8 · see citing works
Dexamethasone enhances phospholipase D activity in M-1 cells
Kim, W.-J., Lee, M.-J., Park, M.-A., Jung, J.-S., Uhlinger, D. J., & Kwak, J. (2000) · Experimental & Molecular Medicine · doi:10.1038/emm.2000.28 · Cited by 7 · see citing works
Self-citationNisimoto, Y., & Ogawa, H. (2002) · European Journal of Biochemistry · doi:10.1046/j.1432-1033.2002.02939.x · Cited by 7 · see citing works
Inflammatory mediators, free radicals and gene transcription
Gilston, V., Blake, D. R., & Winyard, P. G. (2000) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-8482-2_7 · Cited by 6 · see citing works
Wang, J. (2002) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(02)00329-x · Cited by 5 · see citing works
Chang, L., Chen, C., & Wang, J.-P. (2003) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(02)00532-9 · Cited by 5 · see citing works
Gilfillan, A. M. (1997) · Molecular biology intelligence unit · doi:10.1007/978-3-662-22022-1_10 · Cited by 4 · see citing works
Akisue, T., Jinnai, H., Hitomi, T., Miwa, N., Yoshida, K., & Nakamura, S. (1998) · FEBS Letters · doi:10.1016/s0014-5793(97)01611-6 · Cited by 4 · see citing works
A rac-like small G-protein from Brassica campestris activates a PKC-dependent phospholipase D
Kim, H., Nahm, M., Lim, C.-O., Yun, D., Cho, M., & Bahk, J.-D. (2003) · Phytochemistry · doi:10.1016/j.phytochem.2003.10.001 · Cited by 3 · see citing works
Phospholipid‐Derived Second Messengers
Exton, J. H. (1998) · Comprehensive physiology · doi:10.1002/cphy.cp070111 · Cited by 1 · see citing works
Allen, C. E., Kozinetz, C. A., & McClain, K. L. (2008) · Pediatric Blood & Cancer · doi:10.1002/pbc.21541 · Cited by 1 · see citing works
Receptor Regulation of Phospholipases C and D
Schmidt, M., Rümenapp, U., Zhang, C., Keller, J., Lohmann, B., & Jakobs, K. H. (1997) · Springer eBooks · doi:10.1007/978-3-642-60799-8_14
Planat‐Benard, V., Record, M., Tronchère, H., Ribbes, G., & Chap, H. (1996) · Springer eBooks · doi:10.1007/978-1-4615-5875-0_36
- Authors
- Lambeth, J. D., Kwak, J.-Y., Bowman, E. P., Perry, D., Uhlinger, D. J., & Lopez, I.
- Affiliations
- Emory University (US)
- Corresponding author
- Lambeth, J. David
- ORCID
- Kwak, Jong-Young
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1995-02
- Volume
- 270
- Issue
- 6
- Pages
- 2431-2434
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2079169500
- Cited by
- 104
- References
- 31
- Citations by year
- 2021: 1 · 2019: 1 · 2017: 1 · 2013: 1 · 2012: 1
- FWCI
- 8.10
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Biological Chemistry (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01ca046508-13)
- National Cancer Institute (CA46508)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Keywords
- ADP-ribosylation factor, phospholipase D, neutrophils, enzyme activation, cytosolic factors, synergistic activation, Rho GTP-binding proteins, phagocytes, small GTPases
- MeSH terms
- Animals, Cattle, Cell-Free System, Cytosol, Enzyme Activation, Humans, Nerve Tissue Proteins, Neutrophils, Phospholipase D, Subcellular Fractions, GTP-Binding Proteins, ADP-Ribosylation Factors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review