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Characterization of Rac and Cdc42 Activation in Chemoattractant-stimulated Human Neutrophils Using a Novel Assay for Active GTPases
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“deficiency of Rac2 function results in decreased migration and F-actin generation in multiple differentiated blood cell types (10–13, 18).”
From Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization (2001) · cites this paper as [18]
In the citing paper
“As shown in Fig. 4 (lower panel, lane 5), Rac1 activity as measured using the PBD GST pull-down assay (38) in cultured Rac2Ϫ/Ϫ cells increased more than 5-fold compared with in vitro cultured WT cells (lane 1).”
From Biochemical and Biological Characterization of a Human Rac2 GTPase Mutant Associated with Phagocytic Immunodeficiency (2001) · cites this paper as [38]
In the citing paper
“activated (GTP-bound) Cdc42 measured by GST-PAK1 p21-binding domain pull-down (18) was increased by 3- to 20-fold in Rac2−/− cells after exposure to SDF-1, compared with WT cells (Fig. 4A).”
From Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization (2001) · cites this paper as [18]
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Metadata
- Authors
- Benard, V., Bohl, B. P., & Bokoch, G. M.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1999-05
- Volume
- 274
- Issue
- 19
- Pages
- 13198-13204
- ISSN
- 0021-9258
- Cited by
- 645
- References
- 0
- Language
- en
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