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ADAM-TS5, ADAM-TS6, and ADAM-TS7, Novel Members of a New Family of Zinc Metalloproteases
Open accessAbstract
We report the primary structure of three novel, putative zinc metalloproteases designated ADAM-TS5, ADAM-TS6, and ADAM-TS7. All have a similar domain organization, comprising a preproregion, a reprolysin-type catalytic domain, a disintegrin-like domain, a thrombospondin type-1 (TS) module, a cysteine-rich domain, a spacer domain without cysteine residues, and a COOH-terminal TS module. These genes are differentially regulated during mouse embryogenesis and in adult tissues, with Adamts5 highly expressed in the peri-implantation period in embryo and trophoblast. These proteins are similar to four other cognate gene products, defining a distinct family of human reprolysin-like metalloproteases, the ADAM-TS family. The other members of the family are ADAM-TS1, an inflammation-induced gene, the procollagen I/II amino-propeptide processing enzyme (PCINP, ADAM-TS2), and proteins predicted by the KIAA0366 and KIAA0688 genes (ADAM-TS3 and ADAM-TS4). Individual ADAM-TS members differ in the number of COOH-terminal TS modules, and some have unique COOH-terminal domains. The ADAM-TS genes are dispersed in human and mouse genomes.
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Wolfsberg, T. G., Primakoff, P., Myles, D. G., & White, J. M. (1995) · The Journal of cell biology · doi:10.1083/jcb.131.2.275 · Cited by 502
[21] Snake venom metalloendopeptidases: Reprolysins
Bjarnason, J. B., & Fox, J. W. (1995) · Methods in Enzymology · doi:10.1016/0076-6879(95)48023-4 · Cited by 286
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Metadata
- Authors
- Hurskainen, T. L., Hirohata, S., Seldin, M. F., & Apte, S. S.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1999-09
- Volume
- 274
- Issue
- 36
- Pages
- 25555-25563
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2128487191
- Cited by
- 200
- References
- 2
- FWCI
- 5.24
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: ADAM-TS5, ADAM-TS6, and ADAM-TS7, Novel Members of a New Family of Zinc Metalloproteases. https://app.cochat.ai/papers/10.1074/jbc.274.36.25555
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- Hurskainen, T. L., Hirohata, S., Seldin, M. F., & Apte, S. S. (1999). ADAM-TS5, ADAM-TS6, and ADAM-TS7, Novel Members of a New Family of Zinc Metalloproteases. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.274.36.25555
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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