The ADAMTS metalloproteinases

Matrix Metalloproteinases

Nagase, H., & Woessner, J. F. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.31.21491 · Cited by 3,905 · see citing works

Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations

Coussens, L. M., Fingleton, B., & Matrisian, L. M. (2002) · Science · doi:10.1126/science.1067100 · Cited by 2,761 · see citing works

Mendelian Inheritance in Man

MERRITT, A. D. (2011) · Springer eBooks · doi:10.1007/springerreference_33432 · Cited by 2,522 · see citing works

Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

Levy, G. G., Nichols, W. C., Lian, E., Foroud, T., McClintick, J. N., McGee, B. M., Yang, A. Y., Siemieniak, D. R., Stark, K. R., Gruppo, R. A., et al. (2001) · Nature · doi:10.1038/35097008 · Cited by 1,744 · see citing works

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

Van Wart, H. E., & Birkedal-Hansen, H. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.14.5578 · Cited by 1,475 · see citing works

BIOCHEMISTRY AND GENETICS OF VON WILLEBRAND FACTOR

Sadler, J. E. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.395 · Cited by 1,369 · see citing works

Cloning and characterization of chi-1: a developmentally regulated member of a novel class of the ionotropic glutamate receptor family

Ciabarra, A., Sullivan, J., Gahn, L. G., Pecht, G., Heinemann, S., & Sevarino, K. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-10-06498.1995 · Cited by 1,254 · see citing works

Metalloproteinase inhibitors: biological actions and therapeutic opportunities

Baker, A. H., Edwards, D. R., & Murphy, G. (2002) · Journal of Cell Science · doi:10.1242/jcs.00063 · Cited by 1,180 · see citing works

The ADAMs family of metalloproteases: multidomain proteins with multiple functionsPreprint

Seals, D. F., & Courtneidge, S. A. (2003) · Genes & Development · doi:10.1101/gad.1039703 · Cited by 1,058 · see citing works

Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis

Furlan, M., Robles, R., & Lamie, B. (1996) · Blood · doi:10.1182/blood.v87.10.4223.bloodjournal87104223 · Cited by 893 · see citing works

Prediction of the Coding Sequences of Unidentified Human Genes. IX. The Complete Sequences of 100 New cDNA Clones from Brain Which Can Code for Large Proteins in vitro

Nagase, T. (1998) · DNA Research · doi:10.1093/dnares/5.1.31 · Cited by 845 · see citing works

Structure of von Willebrand Factor-cleaving Protease (ADAMTS13), a Metalloprotease Involved in Thrombotic Thrombocytopenic Purpura

Zheng, X. L., Chung, D. W., Τakayama, T. K., Majerus, E. M., Sadler, J. E., & Fujikawa, K. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.c100515200 · Cited by 839 · see citing works

Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion

Tsai, H. (1996) · Blood · doi:10.1182/blood.v87.10.4235.bloodjournal87104235 · Cited by 790 · see citing works

The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases

Stöcker, W., Grams, F., Reinemer, P., Bode, W., Baumann, U., Gomis‐Rüth, F. X., & McKay, D. (1995) · Protein Science · doi:10.1002/pro.5560040502 · Cited by 725 · see citing works

Purification and Cloning of Aggrecanase-1: A Member of the ADAMTS Family of Proteins

Tortorella, M. D., Burn, T. C., Pratta, M. A., Abbaszade, I., Hollis, J. M., Liu, R., Rosenfeld, S. A., Copeland, R. A., Decicco, C. P., Wynn, R., et al. (1999) · Science · doi:10.1126/science.284.5420.1664 · Cited by 686 · see citing works

Purification of human von Willebrand factor–cleaving protease and its identification as a new member of the metalloproteinase family

Fujikawa, K., Suzuki, H., McMullen, B. A., & Chung, D. W. (2001) · Blood · doi:10.1182/blood.v98.6.1662 · Cited by 609 · see citing works

The CUB Domain

Peer Bork, B., & Beckmann, G. (1993) · Journal of Molecular Biology · doi:10.1006/jmbi.1993.1305 · Cited by 582 · see citing works

Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases

Robker, R. L., Russell, D. L., Espey, L. L., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.080073497 · Cited by 550 · see citing works

TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5)

Kashiwagi, M., Tortorella, M. D., Nagase, H., & Brew, K. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.c000848200 · Cited by 509 · see citing works

Molecular Cloning of a Gene Encoding a New Type of Metalloproteinase-disintegrin Family Protein with Thrombospondin Motifs as an Inflammation Associated Gene

Kuno, K., Kanada, N., Nakashima, E., Fujiki, F., Ichimura, F., & Matsushima, K. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.1.556 · Cited by 505 · see citing works

Cloning and Characterization of ADAMTS11 , an Aggrecanase from the ADAMTS Family

Abbaszade, I. G., Liu, R., Yang, F., Rosenfeld, S. A., Ross, O. H., Link, J. R., Ellis, D. M., Tortorella, M. D., Pratta, M. A., Hollis, J. M., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23443 · Cited by 490 · see citing works

Mendelian inheritance in man

Blancato, J. K. (1993) · Reproductive Toxicology · doi:10.1016/0890-6238(93)90275-c · Cited by 455 · see citing works

Versican V1 Proteolysis in Human Aorta in Vivo Occurs at the Glu441-Ala442 Bond, a Site That Is Cleaved by Recombinant ADAMTS-1 and ADAMTS-4

Sandy, J. D., Westling, J., Kenagy, R. D., Iruela‐Arispe, M. L., Verscharen, C., Rodrı́guez-Manzaneque, J. C., Zimmermann, D. R., Lemire, J. M., Fischer, J. W., Wight, T. N., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009737200 · Cited by 454 · see citing works

The functions of thrombospondin-1 and-2

Lawler, J. (2000) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00143-5 · Cited by 441 · see citing works

METH-1, a Human Ortholog of ADAMTS-1, and METH-2 Are Members of a New Family of Proteins with Angio-inhibitory Activity

Vázquez, F., Hastings, G. A., Ortega, M.-A., Lane, T. F., Oikemus, S., Lombardo, M., & Iruela‐Arispe, M. L. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23349 · Cited by 426 · see citing works

Mutations and common polymorphisms in ADAMTS13 gene responsible for von Willebrand factor-cleaving protease activity

Kokame, K., Matsumoto, M., Soejima, K., Yagi, H., Ishizashi, H., Funato, M., Tamai, H., Konno, M., Kamide, K., Kawano, Y., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.172277399 · Cited by 411 · see citing works

Shear stress enhances the proteolysis of von Willebrand factor in normal plasma

Tsai, H., Sussman, I., & Nagel, R. (1994) · Blood · doi:10.1182/blood.v83.8.2171.2171 · Cited by 408 · see citing works

Altered Proteolytic Activities of ADAMTS-4 Expressed by C-terminal Processing

Kashiwagi, M., Enghild, J. J., Gendron, C. M., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312123200 · Cited by 408 · see citing works

Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells.

Reich, R., Thompson, E. W., Iwamoto, Y., et al. (1988) · PubMed · Cited by 406 · see citing works

Expression profiling of metalloproteinases and their inhibitors in cartilage

Kevorkian, L., Young, D. A., Darrah, C., Donell, S. T., Shepstone, L., Porter, S., Brockbank, S., Edwards, D. R., Parker, A. E., & Clark, I. M. (2004) · Arthritis & Rheumatism · doi:10.1002/art.11433 · Cited by 405 · see citing works

Human Ehlers-Danlos Syndrome Type VII C and Bovine Dermatosparaxis Are Caused by Mutations in the Procollagen I N-Proteinase Gene

Colige, A., Sieron, A. L., Li, S.-W., Schwarze, U., Petty, E., Wertelecki, W., Wilcox, W., Krakow, D., Cohn, D. H., Reardon, W., et al. (1999) · The American Journal of Human Genetics · doi:10.1086/302504 · Cited by 370 · see citing works

ADAMTS: a novel family of extracellular matrix proteases

Tang, B. L. (2001) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(00)00061-3 · Cited by 361 · see citing works

A Novel Human Metalloprotease Synthesized in the Liver and Secreted into the Blood: Possibly, the von Willebrand Factor--Cleaving Protease?

Soejima, K., Mimura, N., Hiroshima, M., et al. (2001) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a003009 · Cited by 334 · see citing works

Acquired Deficiency of von Willebrand Factor-Cleaving Protease in a Patient With Thrombotic Thrombocytopenic Purpura

Furlan, M., Robles, R., Solenthaler, M., et al. (1998) · Blood · doi:10.1182/blood.v91.8.2839.2839_2839_2846 · Cited by 331 · see citing works

ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function

Shindo, T., Kurihara, H., Kuno, K., Yokoyama, H., Wada, T., Kurihara, Y., Imai, T., Wang, Y., Ogata, M., Nishimatsu, H., et al. (2000) · Journal of Clinical Investigation · doi:10.1172/jci8635 · Cited by 329 · see citing works

The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation

Tortorella, M. D., Malfait, A., Deccico, C., & Arner, E. C. (2001) · Osteoarthritis and Cartilage · doi:10.1053/joca.2001.0427 · Cited by 327 · see citing works

Characterization of ADAMTS-9 and ADAMTS-20 as a Distinct ADAMTS Subfamily Related to Caenorhabditis elegans GON-1

Somerville, R. P. T., Longpré, J., Jungers, K. A., Engle, J. M., Ross, M., Evanko, S. P., Wight, T. N., Leduc, R., & Apte, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211009200 · Cited by 324 · see citing works

Inhibition of Angiogenesis by Thrombospondin-1 Is Mediated by 2 Independent Regions Within the Type 1 Repeats

Iruela‐Arispe, M. L., Lombardo, M., Krutzsch, H. C., Lawler, J., & Roberts, D. D. (1999) · Circulation · doi:10.1161/01.cir.100.13.1423 · Cited by 308 · see citing works

Aggrecan Protects Cartilage Collagen from Proteolytic Cleavage

Pratta, M. A., Yao, W., Decicco, C. P., Tortorella, M. D., Liu, R.-Q., Copeland, R. A., Magolda, R. L., Newton, R. C., Trzăskos, J. M., & Arner, E. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303737200 · Cited by 292 · see citing works

Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain

Sandy, J. D., Neame, P. J., Boynton, R., et al. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)31499-6 · Cited by 286 · see citing works

ADAMTS10 Mutations in Autosomal Recessive Weill-Marchesani Syndrome

Dagoneau, N., Benoist-Lasselin, C., Huber, C., Faivre, L. O., Mégarbané, A., Alswaid, A. F., Dollfus, H., Alembik, Y., Münnich, A., Legeai‐Mallet, L., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/425231 · Cited by 286 · see citing works

Characterization of and osteoarthritis susceptibility in ADAMTS‐4–knockout mice

Glasson, S. S., Askew, R., Sheppard, B., et al. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20558 · Cited by 283 · see citing works

Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains

Cal, S., Obaya, Á. J., Prada, M. L., Garabaya, C., Quesada, V., & López-Otı́n, C. (2002) · Gene · doi:10.1016/s0378-1119(01)00861-7 · Cited by 273 · see citing works

ADAMTS‐1 cleaves a cartilage proteoglycan, aggrecan

Kuno, K., Okada, Y., Kawashima, H., Nakamura, H., Miyasaka, M., Ohno, H., & Matsushima, K. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01854-8 · Cited by 273 · see citing works

ADAMTS1/METH1 Inhibits Endothelial Cell Proliferation by Direct Binding and Sequestration of VEGF165

Luque, A., Carpizo, D. R., & Iruela‐Arispe, M. L. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212964200 · Cited by 264 · see citing works

Dysregulated Expression of Adamalysin-Thrombospondin Genes in Human Breast Carcinoma

Porter, S., Scott, S. D., Sassoon, E. M., Williams, M. R., Jones, J. L., Girling, A. C., Ball, R. Y., & Edwards, D. R. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-0398-3 · Cited by 246 · see citing works

Sites of Aggrecan Cleavage by Recombinant Human Aggrecanase-1 (ADAMTS-4)

Tortorella, M. D., Pratta, M. A., Liu, R., et al. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m909383199 · Cited by 245 · see citing works

ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors

Rodrı́guez-Manzaneque, J. C., Westling, J., Thai, S. N.-M., Luque, A., Knäuper, V., Murphy, G., Sandy, J. D., & Iruela‐Arispe, M. L. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)00254-1 · Cited by 234 · see citing works

ADAMTS-1 Protein Anchors at the Extracellular Matrix through the Thrombospondin Type I Motifs and Its Spacing Region

Kuno, K., & Matsushima, K. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.22.13912 · Cited by 232 · see citing works

Procollagen II Amino Propeptide Processing by ADAMTS-3

Fernandes, R. J., Hirohata, S., Engle, J. M., Colige, A., Cohn, D. H., Eyre, D. R., & Apte, S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103466200 · Cited by 230 · see citing works

Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura

Klaus, C., Plaimauer, B., Studt, J., et al. (2004) · Blood · doi:10.1182/blood-2003-12-4165 · Cited by 220 · see citing works

von Willebrand factor cleaving protease and ADAMTS13mutations in childhood TTP

Schneppenheim, R., Budde, U., Oyen, F., et al. (2003) · Blood · doi:10.1182/blood-2002-08-2399 · Cited by 218 · see citing works

The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin‐1 and oncostatin M: A time‐course study using real‐time quantitative reverse transcription–polymerase chain reaction

Koshy, P. J. T., Lundy, C. J., Rowan, A. D., Porter, S., Edwards, D. R., Hogan, A., Clark, I. M., & Cawston, T. E. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10212 · Cited by 206 · see citing works

Cleavage of von Willebrand Factor Requires the Spacer Domain of the Metalloprotease ADAMTS13

Zheng, X. L., Nishio, K., Majerus, E. M., & Sadler, J. E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305331200 · Cited by 201 · see citing works

The Thrombospondin Motif of Aggrecanase-1 (ADAMTS-4) Is Critical for Aggrecan Substrate Recognition and Cleavage

Tortorella, M. D., Pratta, M. A., Liu, R., Abbaszade, I. G., Ross, H. O., Burn, T. C., & Arner, E. C. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001065200 · Cited by 200 · see citing works

ADAM-TS5, ADAM-TS6, and ADAM-TS7, Novel Members of a New Family of Zinc Metalloproteases

Hurskainen, T. L., Hirohata, S., Seldin, M. F., & Apte, S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.36.25555 · Cited by 200 · see citing works

Brain-enriched Hyaluronan Binding (BEHAB)/Brevican Cleavage in a Glioma Cell Line Is Mediated by a Disintegrin and Metalloproteinase with Thrombospondin Motifs (ADAMTS) Family Member

Matthews, R. T., Gary, S. C., Zerillo, C. A., Pratta, M. A., Solomon, K. A., Arner, E. C., & Hockfield, S. J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m909764199 · Cited by 197 · see citing works

ADAMTS4 (Aggrecanase-1) Activation on the Cell Surface Involves C-terminal Cleavage by Glycosylphosphatidyl Inositol-anchored Membrane Type 4-Matrix Metalloproteinase and Binding of the Activated Proteinase to Chondroitin Sulfate and Heparan Sulfate on Syndecan-1

Gao, G., Plaas, A., Thompson, V. P., Jin, S., Zuo, F., & Sandy, J. D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312100200 · Cited by 194 · see citing works

Control of organ shape by a secreted metalloprotease in the nematode Caenorhabditis elegans

Blelloch, R. H., & Kimble, J. E. (1999) · Nature · doi:10.1038/21196 · Cited by 192 · see citing works

Subtilase-like pro-protein convertases: from molecular specificity to therapeutic applications

Bergeron, F., Leduc, R., & Day, R. W. (2000) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0240001 · Cited by 184 · see citing works

Activation of the Proteolytic Activity of ADAMTS4 (Aggrecanase-1) by C-terminal Truncation

Gao, G., Westling, J., Thompson, V. P., Howell, T. D., Gottschall, P. E., & Sandy, J. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m107443200 · Cited by 178 · see citing works

Thrombospondins and tumor angiogenesis

de Fraipont, F., Nicholson, A. C., Feige, J., & Meir, E. G. V. (2001) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(01)02102-5 · Cited by 178 · see citing works

Expression and Regulation of Aggrecanase in Arthritis: The Role of TGF-β

Yamanishi, Y., Boyle, D. L., Clark, M. E., Maki, R. A., Tortorella, M. D., Arner, E. C., & Firestein, G. S. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.3.1405 · Cited by 172 · see citing works

cDNA cloning and expression of bovine procollagen I N-proteinase: A new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components

Colige, A., Li, S., Sieroń, A. L., Nusgens, B., Prockop, D. J., & Lapiere, C. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.6.2374 · Cited by 171 · see citing works

Brevican Is Degraded by Matrix Metalloproteinases and Aggrecanase-1 (ADAMTS4) at Different Sites

Nakamura, H., Fujii, Y., Inoki, I., Sugimoto, K., Tanzawa, K., Matsuki, H., Miura, R., Yamaguchi, Y., & Okada, Y. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003875200 · Cited by 168 · see citing works

ADAMTS-1 Is an Active Metalloproteinase Associated with the Extracellular Matrix

Kuno, K., Terashima, Y., & Matsushima, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.26.18821 · Cited by 165 · see citing works

The gon-1 Gene Is Required for Gonadal Morphogenesis in Caenorhabditis elegans

Blelloch, R. H., Anna-Arriola, S. S., Gao, D., Li, Y., Hodgkin, J., & Kimble, J. E. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9491 · Cited by 164 · see citing works

Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases

Kramerova, I. A., Kawaguchi, N., Fessler, L. I., Nelson, R. E., Chen, Y., Kramerov, A. A., Kusche‐Gullberg, M., Kramer, J. M., Ackley, B. D., Sieroń, A. L., et al. (2000) · Development · doi:10.1242/dev.127.24.5475 · Cited by 160 · see citing works

Abnormal Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Brain Arteriovenous Malformations

Hashimoto, T. N., Wen, G., Lawton, M. T., Boudreau, N. J., Bollen, A. W., Yang, G., Barbaro, N. M., Higashida, R. T., Dowd, C. F., Halbach, V. V., et al. (2003) · Stroke · doi:10.1161/01.str.0000061888.71524.df · Cited by 158 · see citing works

Articular cartilage and changes in arthritis: noncollagenous proteins and proteoglycans in the extracellular matrix of cartilage.

Roughley, P. J. (2001) · Arthritis Research · doi:10.1186/ar326 · Cited by 156 · see citing works

Specific Sequence Elements Are Required for the Expression of Functional Tumor Necrosis Factor-α-converting Enzyme (TACE)

Milla, M. E., Leesnitzer, M. A., Moss, M. L., Clay, W. C., Carter, H. L., Miller, A. B., Su, J., Lambert, M. H., Willard, D. H., Sheeley, D. M., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.43.30563 · Cited by 156 · see citing works

ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage

Collins‐Racie, L. A., Flannery, C. R., Zeng, W., Corcoran, C., Annis-Freeman, B., Agostino, M. J., Arai, M., DiBlasio-Smith, E. A., Dorner, A. J., Georgiadis, K. E., et al. (2004) · Matrix Biology · doi:10.1016/j.matbio.2004.05.004 · Cited by 154 · see citing works

Characterization of METH-1/ADAMTS1 Processing Reveals Two Distinct Active Forms

Rodrı́guez-Manzaneque, J. C., Milchanowski, A. B., Dufour, E. K., Leduc, R., & Iruela‐Arispe, M. L. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002599200 · Cited by 151 · see citing works

Autocatalytic Cleavage of ADAMTS-4 (Aggrecanase-1) Reveals Multiple Glycosaminoglycan-binding Sites

Flannery, C. R., Zeng, W., Corcoran, C., Collins‐Racie, L. A., Chockalingam, P. S., Hebert, T., Mackie, S. A., McDonagh, T., Crawford, T. K., Tomkinson, K. N., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205309200 · Cited by 150 · see citing works

α2-Macroglobulin Is a Novel Substrate for ADAMTS-4 and ADAMTS-5 and Represents an Endogenous Inhibitor of These Enzymes

Tortorella, M. D., Arner, E. C., Hills, R. L., Easton, A. M., Korte-Sarfaty, J., Fok, K. F., Wittwer, A. J., Liu, R., & Malfait, A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313041200 · Cited by 143 · see citing works

Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility

Shi-Wu, L. I., ARITA, M., Fertala, A., Bao, Y., Kopen, G. C., Långsjö, T. K., Hyttinen, M. M., Helminen, H. J., & Prockop, D. J. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3550271 · Cited by 143 · see citing works

Ovarian Expression of a Disintegrin and Metalloproteinase with Thrombospondin Motifs During Ovulation in the Gonadotropin-Primed Immature Rat1

Espey, L. L., Yoshioka, S., Russell, D. L., Robker, R. L., Fujii, S., & Richards, J. S. (2000) · Biology of Reproduction · doi:10.1095/biolreprod62.4.1090 · Cited by 141 · see citing works

Generation and Characterization of Aggrecanase

Arner, E. C., Pratta, M. A., Trzăskos, J. M., Decicco, C. P., & Tortorella, M. D. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.10.6594 · Cited by 132 · see citing works

Cleavage of the ADAMTS13 Propeptide Is Not Required for Protease Activity

Majerus, E. M., Zheng, X. L., Tuley, E. A., & Sadler, J. E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m309872200 · Cited by 129 · see citing works

Proprotein Convertase Furin Interacts with and Cleaves Pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi Network

Wang, P., Tortorella, M. D., England, K. A., Malfait, A., Thomas, G., Arner, E. C., & Pei, D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312797200 · Cited by 122 · see citing works

ADAMTS1: A Matrix Metalloprotease with Angioinhibitory Properties

Iruela‐Arispe, M. L., Carpizo, D. R., & Luque, A. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb03221.x · Cited by 116 · see citing works

Expression of METH-1 and METH-2 in pancreatic cancer

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A defect in a novel ADAMTS family member is the cause of the belted white-spotting mutation

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Identification and Characterization of ADAMTS-20 Defines a Novel Subfamily of Metalloproteinases-Disintegrins with Multiple Thrombospondin-1 Repeats and a Unique GON Domain

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Metalloproteinase Expression in PMA-stimulated THP-1 Cells

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Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility

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Selective inhibition of ADAMTS‐1, ‐4 and ‐5 by catechin gallate esters

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TIMP‐3 inhibits aggrecanase‐mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors

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Discovery and Characterization of a Novel, Widely Expressed Metalloprotease, ADAMTS10, and Its Proteolytic Activation

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Familial acquired thrombotic thrombocytopenic purpura: ADAMTS13 inhibitory autoantibodies in identical twins

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Detailed deletion mapping of chromosome arm 3p in breast cancers: A 2-cM region on 3p14.3-21.1 and a 5-cM region on 3p24.3-25.1 commonly deleted in tumors

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Identification of Aggrecanase Activity in Medium of Cartilage Culture

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Thyroid Hormone Enhances Aggrecanase-2/ADAM-TS5 Expression and Proteoglycan Degradation in Growth Plate Cartilage

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The Propeptide Domain of Membrane Type 1-Matrix Metalloproteinase Acts as an Intramolecular Chaperone when Expressed in transwith the Mature Sequence in COS-1 Cells

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Cloning and characterization of a cDNA coding for Astacus embryonic astacin, a member of the astacin family of metalloproteases from the crayfish Astacus astacus

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The Caenorhabditis elegans ADAMTS Family Gene adt-1 Is Necessary for Morphogenesis of the Male Copulatory Organs

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A novel disintegrin domain protein affects early cell type specification and pattern formation inDictyostelium

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Extracellular Matrix Assembly: A Multiscale Deconstruction

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Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions

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Synaptopathies: synaptic dysfunction in neurological disorders – A review from students to students

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Losing the sugar coating: Potential impact of perineuronal net abnormalities on interneurons in schizophrenia

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A Disintegrin and Metalloproteinase (ADAM) and ADAM with thrombospondin motifs (ADAMTS) family in vascular biology and disease

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Reciprocal Interplay Between Fibrillar Collagens and Collagen‐Binding Integrins: Implications in Cancer Progression and Metastasis

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The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional recovery after spinal cord injury

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Discordant localization of WFA reactivity and brevican/ADAMTS-derived fragment in rodent brain

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ADAMTSL3 as a candidate gene for schizophrenia: gene sequencing and ultra-high density association analysis by imputation

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Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia

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Pathophysiological function of ADAMTS enzymes on molecular mechanism of Alzheimer’s disease

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Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression

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Genetic variations in the ADAMTS12 gene are associated with schizophrenia in Puerto Rican patients of Spanish descent

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ADAMTS: a novel family of extracellular matrix proteases

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The Research of A Disintegrin-like and Metalloproteinase with Thrombospondin Type 1 Motifs

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ADAMTS‐5: A difficult teenager turning 20

Santamaria, S. (2020) · International Journal of Experimental Pathology · doi:10.1111/iep.12344 · Cited by 71 · see citing works

The role of A Disintegrin and Metalloproteinase with Thrombospondin Motifs-15 (ADAMTS-15) in Breast Cancer

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A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers

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