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Cited by 341

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Four New Members Expand the Interleukin-1 Superfamily

Open access
Smith, Dirk E., Renshaw, Blair R., Ketchem, Randal R., Kubin, Marek, Garka, Kirsten E., Sims, John E.·2000·Journal of Biological Chemistry

Abstract

We report here the cloning and characterization of four new members of the interleukin-1 (IL-1) family (FIL1delta, FIL1epsilon, FIL1zeta, and FIL1eta, with FIL1 standing for "Family of IL-1"). The novel genes demonstrate significant sequence similarity to IL-1alpha, IL-1beta, IL-1ra, and IL-18, and in addition maintain a conserved exon-intron arrangement that is shared with the previously known members of the family. Protein structure modeling also suggests that the FIL1 genes are related to IL-1beta and IL-1ra. The novel genes form a cluster with the IL-1s on the long arm of human chromosome 2.

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Metadata

Authors
Smith, D. E., Renshaw, B. R., Ketchem, R. R., Kubin, M., Garka, K. E., & Sims, J. E.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
2000-01
Volume
275
Issue
2
Pages
1169-1175
ISSN
0021-9258 (ISSN-L)
OpenAlex
W2152486718
Cited by
341
References
2
FWCI
8.91
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Four New Members Expand the Interleukin-1 Superfamily. https://app.cochat.ai/papers/10.1074/jbc.275.2.1169
The paper
Smith, D. E., Renshaw, B. R., Ketchem, R. R., Kubin, M., Garka, K. E., & Sims, J. E. (2000). Four New Members Expand the Interleukin-1 Superfamily. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.275.2.1169

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.