The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Reprimo, a New Candidate Mediator of the p53-mediated Cell Cycle Arrest at the G2 Phase
Open accessAbstract
A novel gene, Reprimo, in which induction in cells exposed to X-irradiation is dependent on p53 expression, has been isolated. Ectopic p53 expression results in the induction of its mRNA. Reprimo is a highly glycosylated protein and, when ectopically expressed, it is localized in the cytoplasm and induces G(2) arrest of the cell cycle. In the arrested cells, both Cdc2 activity and nuclear translocation of cyclin B1 are inhibited, suggesting the involvement of Reprimo in the Cdc2.cyclin B1 regulation pathway. Thus, Reprimo may be a new member involved in the regulation of p53-dependent G(2) arrest of the cell cycle.
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“Reprimo is also involved in p53-induced cell cycle arrest in the G2 phase.66”
From Targeting p53 pathways: mechanisms, structures, and advances in therapy (2023) · cites this paper as [66]
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Cites
p53 Mutations in Human Cancers
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14-3-3σ is required to prevent mitotic catastrophe after DNA damage
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Self-citationCyclin G is a transcriptional target of the p53 tumor suppressor protein.
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Cited by
Vogelstein, B., Lane, D., & Levine, A. J. (2000) · Nature · doi:10.1038/35042675 · Cited by 6,607
Targeting p53 pathways: mechanisms, structures, and advances in therapy
Wang, H., Guo, M., Wei, H., & Chen, Y. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01347-1 · Cited by 1,016
Role of p53 in Cell Death and Human Cancers
Ozaki, T., & Nakagawara, A. (2011) · Cancers · doi:10.3390/cancers3010994 · Cited by 650
Signaling pathways and therapeutic interventions in gastric cancer
Lei, Z.-N., Teng, Q.-X., Tian, Q., Chen, W., Xie, Y., Wu, K., Zeng, Q., Zeng, L., Pan, Y., Chen, Z.-S., et al. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01190-w · Cited by 322
Krones-Herzig, A., Adamson, E., & Mercola, D. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2628034100 · Cited by 118
Metadata
- Authors
- Ohki, R., Nemoto, J., Murasawa, H., Oda, E., Inazawa, J., Tanaka, N., & Taniguchi, T.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2000-07
- Volume
- 275
- Issue
- 30
- Pages
- 22627-22630
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2020630430
- Cited by
- 208
- References
- 7
- FWCI
- 3.38
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Ohki, R., Nemoto, J., Murasawa, H., Oda, E., Inazawa, J., Tanaka, N., & Taniguchi, T. (2000). Reprimo, a New Candidate Mediator of the p53-mediated Cell Cycle Arrest at the G2 Phase. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.c000235200
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
