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Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression

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SWI/SNF Complex Interacts with Tumor Suppressor p53 and Is Necessary for the Activation of p53-mediated Transcription

Lee, D., Kim, J. W., Seo, T., Hwang, S. G., Choi, E., & Choe, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111987200 · Cited by 230 · see citing works

Cell type‐specific inhibition of p53‐mediated apoptosis by mdm2.

Haupt, Y., Barak, Y., & Oren, M. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00504.x · Cited by 228 · see citing works

Cyclins and Cell Cycle Control in Cancer and Disease

Casimiro, M., Crosariol, M., Loro, E., Li, Z., & Pestell, R. G. (2012) · Genes & Cancer · doi:10.1177/1947601913479022 · Cited by 219 · see citing works

Cyclin G Recruits PP2A to Dephosphorylate Mdm2

Okamoto, K., Li, H., Jensen, M. R., Zhang, T., Taya, Y., Thorgeirsson, S. S., & Prives, C. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00504-x · Cited by 215 · see citing works

Transcription Factor E2F-1 Is Upregulated in Response to DNA Damage in a Manner Analogous to That of p53

Blattner, C., Sparks, A., & Lane, D. P. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.5.3704 · Cited by 213 · see citing works

Cyclin G2 Associates with Protein Phosphatase 2A Catalytic and Regulatory B′ Subunits in Active Complexes and Induces Nuclear Aberrations and a G1/S Phase Cell Cycle Arrest

Bennin, D. A., Don, A. S. A., Brake, T., McKenzie, J. L., Rosenbaum, H., Ortiz, L., DePaoli-Roach, A. A., & Horne, M. C. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111693200 · Cited by 210 · see citing works

Comparative Binding of p53 to its Promoter and DNA Recognition Elements

Weinberg, R. L., Veprintsev, D. B., Bycroft, M., & Fersht, A. R. (2005) · Journal of Molecular Biology · doi:10.1016/j.jmb.2005.03.014 · Cited by 206 · see citing works

Reprimo, a New Candidate Mediator of the p53-mediated Cell Cycle Arrest at the G2 Phase

Ohki, R., Nemoto, J., Murasawa, H., Oda, E., Inazawa, J., Tanaka, N., & Taniguchi, T. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.c000235200 · Cited by 201 · see citing works

Transcriptional Activation of the Human Epidermal Growth Factor Receptor Promoter by Human p53

Ludes-Meyers, J. H., Subler, M. A., Shivakumar, C. V., Muñoz, R. M., Jiang, P., Bigger, J. E., Brown, D. R., Deb, S. P., & Deb, S. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.11.6009 · Cited by 181 · see citing works

The role of p53-target genes in human cancer

Tokino, T., & Nakamura, Y. (2000) · Critical Reviews in Oncology/Hematology · doi:10.1016/s1040-8428(99)00051-7 · Cited by 173 · see citing works

A novel p53‐inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis

Israeli, D., Tessler, E., Haupt, Y., Elkeles, A., Wilder, S., Amson, R. B., Telerman, A., & Oren, M. (1997) · The EMBO Journal · doi:10.1093/emboj/16.14.4384 · Cited by 172 · see citing works

Regulation of p53 by Metal Ions and by Antioxidants: Dithiocarbamate Down-Regulates p53 DNA-Binding Activity by Increasing the Intracellular Level of Copper

Verhaegh, G. W. C. T., Richard, M., & Hainaut, P. L. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.10.5699 · Cited by 168 · see citing works

<scp>RNA</scp> ‐seq of the aging brain in the short‐lived fish <i>N. furzeri</i> – conserved pathways and novel genes associated with neurogenesis

Baumgart, M., Groth, M., Priebe, S., Savino, A., Testa, G., Dix, A., Ripa, R., Spallotta, F., Gaetano, C., Ori, M., et al. (2014) · Aging Cell · doi:10.1111/acel.12257 · Cited by 167 · see citing works

The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells

Wang, Q., Zou, Y., Nowotschin, S., Kim, S. Y., Li, Q. V., Soh, C.-L., Su, J., Zhang, C., Shu, W., Xi, Q., et al. (2016) · Cell stem cell · doi:10.1016/j.stem.2016.10.002 · Cited by 163 · see citing works

Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: activation of the vertebrate homologue of the drosophila seven in absentia gene.

Amson, R. B., Nemani, M., Roperch, J.-P., Israeli, D., Bougueleret, L., Gall, I. L., Medhioub, M., Linares‐Cruz, G., Lethrosne, F., Pasturaud, P., et al. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.9.3953 · Cited by 162 · see citing works

p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents

Thottassery, J. V., Zambetti, G. P., Arimori, K., Schuetz, E. G., & Schuetz, J. D. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.20.11037 · Cited by 161 · see citing works

Cyclin G1 and Cyclin G2 Comprise a New Family of Cyclins with Contrasting Tissue-specific and Cell Cycle-regulated Expression

Horne, M. C., Goolsby, G. L., Donaldson, K. L., Tran, D., Neubauer, M., & Wahl, A. F. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.11.6050 · Cited by 160 · see citing works

Proteolysis by Calpains: a Possible Contribution to Degradation of p53

Pariât, M., Carillo, S., Molinari, M., Salvat, C., Debüssche, L., Bracco, L. P., Milner, J., & Piechaczyk, M. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.5.2806 · Cited by 160 · see citing works

Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expression

Okamoto, T., Izumi, H., Imamura, T., Takano, H., Ise, T., Uchiumi, T., Kuwano, M., & Kohno, K. (2000) · Oncogene · doi:10.1038/sj.onc.1204029 · Cited by 159 · see citing works

Adenovirus E1B 55K Represses p53 Activation In Vitro

Martin, M. E. D., & Berk, A. J. (1998) · Journal of Virology · doi:10.1128/jvi.72.4.3146-3154.1998 · Cited by 158 · see citing works

Analysing differential gene expression in cancer

Liang, P., & Pardee, A. B. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1214 · Cited by 156 · see citing works

p53 Negatively Regulates cdc2 Transcription via the CCAAT-binding NF-Y Transcription Factor

Yun, J., Chae, H., Choy, H. E., Chung, J., Yoo, H., Han, M.-H., & Shin, D. Y. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.42.29677 · Cited by 155 · see citing works

The transcription factor p53: Not a repressor, solely an activator.

Fischer, M., Steiner, L., & Engeland, K. (2014) · Cell Cycle · doi:10.4161/15384101.2014.949083 · Cited by 153 · see citing works

The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract

Sheikh, M. S., Huang, Y., Fernández‐Salas, E., El‐Deiry, W. S., Friess, H., Amundson, S. A., Yin, J., Meltzer, S. J., Holbrook, N. J., & Fornace, A. J. (1999) · Oncogene · doi:10.1038/sj.onc.1202763 · Cited by 150 · see citing works

p53-dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells

Zamble, D. B., Jacks, T., & Lippard, S. J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.6163 · Cited by 149 · see citing works

Inhibition of DNA Topoisomerase IIα Gene Expression by the p53 Tumor Suppressor

Wang, Q., Zambetti, G. P., & Suttle, D. P. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.1.389 · Cited by 149 · see citing works

Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery

Kimura, S. H., Ikawa, M., Ito, A., Okabe, M., & Nojima, H. (2001) · Oncogene · doi:10.1038/sj.onc.1204270 · Cited by 148 · see citing works

Involvement of the Fas/Fas Ligand System in p53-Mediated Granulosa Cell Apoptosis during Follicular Development and Atresia

Kim, J. M., Yoon, Y., & Tsang, B. K. (1999) · Endocrinology · doi:10.1210/en.140.5.2307 · Cited by 147 · see citing works

Efficient Specific DNA Binding by p53 Requires both Its Central and C-Terminal Domains as Revealed by Studies with High-Mobility Group 1 Protein

McKinney, K. M., & Prives, C. L. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.19.6797-6808.2002 · Cited by 146 · see citing works

Differential regulation of plasminogen activator and inhibitor gene transcription by the tumor suppressor p53

Kunz, C., Pebler, S., Otte, J., & von der Ahe, D. (1995) · Nucleic Acids Research · doi:10.1093/nar/23.18.3710 · Cited by 144 · see citing works

The loss of mdm2 induces p53 mediated apoptosis

de Rozìeres, S., Maya, R. B.-Y., Oren, M., & Lozano, G. (2000) · Oncogene · doi:10.1038/sj.onc.1203468 · Cited by 144 · see citing works

The Role of p53 in Cell Cycle Regulation

Shaw, P. H. (1996) · Pathology - Research and Practice · doi:10.1016/s0344-0338(96)80088-4 · Cited by 144 · see citing works

Molecular Cloning and Biochemical Characterization of a Novel Anthocyanin 5-O-Glucosyltransferase by mRNA Differential Display for Plant Forms Regarding Anthocyanin

Yamazaki, M., Gong, Z., Fukuchi‐Mizutani, M., Fukui, Y., Tanaka, Y., Kusumi, T., & Saito, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.11.7405 · Cited by 144 · see citing works

Identification of rCop-1, a New Member of the CCN Protein Family, as a Negative Regulator for Cell Transformation

Zhang, R., Averboukh, L., Zhu, W., Zhang, H., Jo, H., Dempsey, P. J., Coffey, R. J., Pardee, A. B., & Liang, P. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.10.6131 · Cited by 144 · see citing works

p53 Down-regulates Human Matrix Metalloproteinase-1 (Collagenase-1) Gene Expression

Sun, Y., Sun, Y., Wenger, L., Rutter, J. L., Brinckerhoff, C., & Cheung, H. S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.17.11535 · Cited by 143 · see citing works

Protein phosphatase 2A: Who shall regulate the regulator?

Goldberg, Y. (1999) · Biochemical Pharmacology · doi:10.1016/s0006-2952(98)00245-7 · Cited by 138 · see citing works

Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-κB and Myc/Max

Kirch, H.-C., Flaswinkel, S., Rumpf, H., Brockmann, D., & Esche, H. (1999) · Oncogene · doi:10.1038/sj.onc.1202626 · Cited by 135 · see citing works

Biogenesis of p53 Involves Cotranslational Dimerization of Monomers and Posttranslational Dimerization of Dimers

Nicholls, C. D., McLure, K. G., Shields, M. A., & Lee, P. W. K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m108815200 · Cited by 134 · see citing works

Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint

Bruno, T., Nicola, F. D., Iezzi, S., Lecis, D., D’Angelo, C., Padova, M. D., Corbi, N., Dimiziani, L., Zannini, L., Jekimovs, C., et al. (2006) · Cancer Cell · doi:10.1016/j.ccr.2006.10.012 · Cited by 128 · see citing works

Tumor-suppressor p53 is expressed in proliferating and newly formed neurons of the embryonic and postnatal rat brain: Comparison with expression of the cell cycle regulators p21Waf1/Cip1, p27Kip1, p57Kip2, p16Ink4a, cyclin G1, and the proto-oncogene bax

Campagne, M. V. L., & Gill, R. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19980727)397:2 · Cited by 127 · see citing works

Classic and novel roles of p53: prospects for anticancer therapy

Fuster, J. J., Sanz-Gonzalez, S. M., Moll, U. M., & Andrés, V. (2007) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2007.03.002 · Cited by 126 · see citing works

Identification of p53 target genes through immune selection of genomic DNA: the cyclin G gene contains two distinct p53 binding sites.

Zauberman, A., Lupo, A., & Oren, M. (1995) · PubMed · Cited by 134 · see citing works

Cyclin K as a Direct Transcriptional Target of the p53 Tumor Suppressor

Mori, T., Anazawa, Y., Matsui, K., Fukuda, S., Nakamura, Y., & Arakawa, H. (2002) · Neoplasia · doi:10.1038/sj.neo.7900235 · Cited by 48 · see citing works

The tumour suppressor protein p53 can repress transcription of cyclin B

Krause, K. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.22.4410 · Cited by 170 · see citing works

The proliferation-associated early response gene p22/PRG1 is a novel p53 target gene

Schäfer, H., Trauzold, A., Sebens, T., Deppert, W., Fölsch, U. R., & Schmidt, W. E. (1998) · Oncogene · doi:10.1038/sj.onc.1201788 · Cited by 41 · see citing works

p53 is a NF‐Y‐ and p21‐independent, Sp1‐dependent repressor of cyclin B1 transcription

Innocente, S. A., & Lee, J. M. (2005) · FEBS Letters · doi:10.1016/j.febslet.2004.12.073 · Cited by 87 · see citing works