Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing.

Cited by (351)

Items 101–200 of 351

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7. Differing impact of the deletion of hemochromatosis‐associated molecules HFE and transferrin receptor‐2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin
   Chloé Latour, Céline Besson‐Fournier, Delphine Meynard, Laura Silvestri, Ophélie Gourbeyre, Patricia Aguilar‐Martinez, Paul Joseph Schmidt, Mark D. Fleming, Marie‐Paule Roth, Hélène Coppin · 2015 · Hepatology
8. Hepcidin regulates intrarenal iron handling at the distal nephron
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9. Iron homeostasis: new players, newer insights
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10. Transferrin-a modulates hepcidin expression in zebrafish embryos
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11. Iron Pathophysiology in Alzheimer’s Diseases
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12. The mechanisms of systemic iron homeostasis and etiology, diagnosis, and treatment of hereditary hemochromatosis
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13. The changing landscape of iron deficiency
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14. Iron Metabolism in Man
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15. Molecular Evolution of the Transferrin Receptor/Glutamate Carboxypeptidase II Family
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16. Modulation of hepcidin to treat iron deregulation: potential clinical applications
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17. Diagnostic value of transferrin
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18. Liver transplantation normalizes serum hepcidin level and cures iron metabolism alterations in HFE hemochromatosis
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19. Disorders associated with systemic or local iron overload: from pathophysiology to clinical practice
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20. Iron Biology, Immunology, Aging, and Obesity: Four Fields Connected by the Small Peptide Hormone Hepcidin
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21. Chapter 6 Iron Homeostasis and Erythropoiesis
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22. Measurement of urinary hepcidin levels by SELDI-TOF-MS in HFE-hemochromatosis
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23. Cell‐type‐specific insights into iron regulatory processes
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24. Hereditary hemochromatosis: insights from the Hemochromatosis and Iron Overload Screening (HEIRS) Study
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25. Ferristatin II Promotes Degradation of Transferrin Receptor-1 In Vitro and In Vivo
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26. Transgenic HFE‐dependent induction of hepcidin in mice does not require transferrin receptor‐2
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27. Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations
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28. Hemochromatosis Gene Polymorphisms, Mitochondrial Haplogroups, and Peripheral Lipoatrophy during Antiretroviral Therapy
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30. Role of duodenal iron transporters and hepcidin in patients with alcoholic liver disease
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31. The extrahepatic role of TFR2 in iron homeostasis
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32. Oncostatin M is a potent inducer of hepcidin, the iron regulatory hormone
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33. Association between the HFE C282Y, H63D Polymorphisms and the Risks of Non-Alcoholic Fatty Liver Disease, Liver Cirrhosis and Hepatocellular Carcinoma: An Updated Systematic Review and Meta-Analysis of 5,758 Cases and 14,741 Controls
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34. Iron and inflammation – the gut reaction
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35. Function of the hemochromatosis protein HFE: Lessons from animal models
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36. In Situ Proximity Ligation Assays Indicate That Hemochromatosis Proteins Hfe and Transferrin Receptor 2 (Tfr2) Do Not Interact
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37. Factors influencing disease phenotype and penetrance in HFE haemochromatosis
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39. Iron Deficiency Anaemia
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40. Iron storage disease in A sia‐ P acific populations: The importance of non‐ HFE mutations
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41. Molecular basis of HFE-hemochromatosis
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42. The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system
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43. The global burden of iron overload
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44. Non-HFE hemochromatosis: Pathophysiological and diagnostic aspects
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45. Managing the Dual Nature of Iron to Preserve Health
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46. Genetic and Dietary Iron Overload Differentially Affect the Course of Salmonella Typhimurium Infection
    Nairz, Manfred, Schroll, Andrea, Haschka, David, Dichtl, Stefanie, Tymoszuk, Piotr, Demetz, Egon, Moser, Patrizia, Haas, Hubertus, Fang, Ferric C., Theurl, Igor et al. · 2017 · Frontiers in Cellular and Infection Microbiology
47. Modulation of Hepcidin as Therapy for Primary and Secondary Iron Overload Disorders
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48. Iron responses in hepatic, intestinal and macrophage/monocyte cell lines under different culture conditions
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49. HFEgene in primary and secondary hepatic iron overload
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50. Iron as a therapeutic target in chronic liver disease
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51. Hereditary hemochromatosis and transferrin receptor 2
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52. Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes
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53. Mitochondrial reactive oxygen species and heme, non-heme iron metabolism
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54. The role of MHC class Ib-restricted T cells during infection
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55. Blood Iron Homeostasis: Newly Discovered Proteins and Iron Imbalance
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56. Tumor Necrosis Factor α Inhibits Expression of the Iron Regulating Hormone Hepcidin in Murine Models of Innate Colitis
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57. The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice
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58. Molecular mechanisms of hepcidin regulation in sea bass (Dicentrarchus labrax)
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59. A novel mutation of transferrin receptor 2 in a Taiwanese woman with type 3 hemochromatosis
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60. Molecular basis of the structural stability of hemochromatosis factor E : A combined molecular dynamic simulation and GdmCl‐induced denaturation study
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62. Regulation of Iron Absorption in Hemoglobinopathies
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63. Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin
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67. Diagnostic Evaluation of Hereditary Hemochromatosis (HFE and Non-HFE)
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68. Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response
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69. Iron Nutrition, Oxidative Stress, and Pathogen Defense
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70. Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders
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71. Next-generation sequencing: Application of a novel platform to analyze atypical iron disorders
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82. Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin
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83. Signaling pathways regulating hepcidin
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84. Iron Metabolism, Iron Deficiency and Disorders of Haem Synthesis
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89. Potential of biogas production from manure of dairy cattle fed on natural soil supplement rich in iron under batch and semi-continuous anaerobic digestion
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90. Defective trafficking and localization of mutated transferrin receptor 2: implications for type 3 hereditary hemochromatosis
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91. Molecular regulation of hepatic expression of iron regulatory hormone hepcidin
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92. The WT hemochromatosis protein HFE inhibits CD8+ T‐lymphocyte activation
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95. Stoichiometries of transferrin receptors 1 and 2 in human liver
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96. Iron metabolism gene expression in human skeletal muscle
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99. DNA methylation of hepatic iron sensing genes and the regulation of hepcidin expression
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100. Actualité du métabolisme du fer
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