Molecular Cloning, Chromosomal Localization, Tissue mRNA Levels, Bacterial Expression, and Enzymatic Properties of Human NMN Adenylyltransferase

Cited by (188)

Items 101–188 of 188

1. Overexpression of Wlds or Nmnat2 in mauthner cells by single‐cell electroporation delays axon degeneration in live zebrafish
   Yan Feng, Tingting Yan, Jin Huan Zheng, Xinjian Ge, Yu Mu, Yi Zhang, Dongmei Wu, Jiulin Du, Qiwei Zhai · 2010 · Journal of Neuroscience Research
2. Contribution of insulin resistance to vascular dysfunction
   Giovanni Anfossi, Isabella Russo, Gabriella Doronzo, Mariella Trovati · 2009 · Archives of Physiology and Biochemistry
3. Inflammation and impaired endothelium-dependant vasodilatation in non obese women with gestational diabetes mellitus: preliminary results
   Ines Mrizak, Amel Arfa, Mariem Fekih, Haythem Debbabi, Ali Bouslema, Imen Boumaiza, Monia Zaouali, Naim A. Khan, Zouhaïr Tabka · 2013 · Lipids in Health and Disease
4. Metabolic syndrome: is equine disease comparable to what we know in humans?
   Antonia Ertelt, Ann Kristin Barton, Robert R Schmitz, Heidrun Gehlen · 2014 · Endocrine Connections
5. Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN
   Erik Werner, Mathias Ziegler, Felicitas Lerner, Manfred Schweiger, Udo Heinemann · 2002 · FEBS Letters
6. NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
   Antonio Lucena-Cacace, Masayuki Umeda, Lola E. Navas, Amancio Carnero · 2019 · Frontiers in Oncology
7. Leptin regulation of lipid homeostasis: dietary and metabolic implications
   Karen L. Houseknecht, Michael E. Spurlock · 2003 · Nutrition Research Reviews
8. Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidation
   Lynn‐Jee Kim, Timothy J. Chalmers, Romanthi J. Madawala, Greg C. Smith, Catherine Li, Abhirup Das, Eric Wing Keung Poon, Jun Wang, Simon P. Tucker, David A. Sinclair et al. · 2023 · FEBS Letters
9. Balancing NAD+ deficits with nicotinamide riboside: therapeutic possibilities and limitations
   Angelique Cercillieux, Eleonora Ciarlo, Carles Cantó · 2022 · Cellular and Molecular Life Sciences
10. NAD + and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents
    William T. Harkcom, Ananda Kumar Ghosh, Matthew S. Sung, Alexandre Matov, Kevin D. Brown, Paraskevi Giannakakou, Samie R. Jaffrey · 2014 · Proceedings of the National Academy of Sciences
11. Targeting PPARβ/δ for the treatment of type 2 diabetes mellitus
    Laia Salvadó, Lucía Serrano, Emma Barroso, Xavier Palomer, Manuel Vázquez‐Carrera · 2012 · Expert Opinion on Therapeutic Targets
12. Vitamin A Transport and Cell Signaling by the Retinol-Binding Protein Receptor STRA6
    Noa Noy · 2016 · Sub-cellular biochemistry/Subcellular biochemistry
13. NAD+ Accumulation during Pollen Maturation in Arabidopsis Regulating Onset of Germination
    Shin‐nosuke Hashida, Hideyuki Takahashi, Kentaro Takahara, Maki Kawai‐Yamada, Kazuyoshi Kitazaki, Kazuhiro Shoji, Fumiyuki Goto, Toshihiro Yoshihara, Hirofumi Uchimiya · 2012 · Molecular Plant
14. Hypogonadotrophic hypogonadism in type 2 diabetes
    Paresh Dandona, Sandeep Dhindsa, A. Chaudhuri, Vineet Bhatia, Shehzad Topiwala · 2008 · The Aging Male
15. The function of nicotinamide phosphoribosyltransferase in the heart
    Chiao-Po Hsu, Takanobu Yamamoto, Shinichi Oka, Junichi Sadoshima · 2014 · DNA repair
16. NMN/NaMN Adenylyltransferase (NMNAT) and NAD Kinase (NADK) Inhibitors: Chemistry and Potential Therapeutic Applications
    Riccardo Petrelli, Krzysztof Felczak, Loredana Cappellacci · 2011 · Current Medicinal Chemistry
17. Identification and characterization of a second NMN adenylyltransferase gene in Saccharomyces cerevisiae
    Monica Emanuelli, Adolfo Amici, Francesco Carnevali, Francesca Pierella, Nadia Raffaelli, Giulio Magni · 2003 · Protein Expression and Purification
18. Tumor necrosis factor superfamily molecules in acute coronary syndromes
    Pål Aukrust, Wiggo J. Sandberg, Kari Otterdal, Leif Erik Vinge, Lars Lysgaard Gullestad, Arne Yndestad, Bente Lise Halvorsen, Thor Ueland · 2010 · Annals of Medicine
19. The key role of the NAD biosynthetic enzyme nicotinamide mononucleotide adenylyltransferase in regulating cell functions
    Carlo Fortunato, Francesca Mazzola, Nadia Raffaelli · 2021 · IUBMB Life
20. Nicotinamide Adenine Dinucleotide: The Redox Sensor in Aging-Related Disorders
    Giovanna Schiuma, Djidjell Lara, James Premdoss Clement, Marco Narducci, Roberta Rizzo · 2024 · Antioxidants and Redox Signaling
21. Identification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1
    Euan Parnell, Stuart P. McElroy, Jolanta Wiejak, Gemma L. Baillie, Alison Porter, David R. Adams, Holger Rehmann, Brian O. Smith, Stephen J. Yarwood · 2017 · Scientific Reports
22. Identification of a critical site in Wlds: Essential for Nmnat enzyme activity and axon-protective function
    Haiqun Jia, Tingting Yan, Yan Feng, Cheng‐Ming Zeng, Xianglin Shi, Qiwei Zhai · 2006 · Neuroscience Letters
23. The suppressor of cytokine signalling 2 (SOCS2) is a key repressor of insulin secretion
    P. Lebrun, Emmanuelle Cognard, P. Gontard, Rachel Paul, Chantal Filloux, Marie‐France Berthault, Chr̀istophe Magnan, Jesús Ruberte, Mariana López‐Luppo, Anna Pujol et al. · 2010 · Diabetologia
24. PARylation During Transcription: Insights into the Fine-Tuning Mechanism and Regulation
    Zoltán Gábor Páhi, Barbara Nikolett Borsos, Vasiliki Pantazi, Zsuzsanna Újfaludi, Tibor Pankotai · 2020 · Cancers
25. NAD+ metabolism is a key modulator of bacterial respiratory epithelial infections
    Björn Klabunde, Andre Wesener, Wilhelm Bertrams, Isabell Beinborn, Nicole Paczia, Kristin Surmann, Sascha Blankenburg, Jochen Wilhelm, Javier Serranía, Kèvin Knoops et al. · 2023 · Nature Communications
26. Constitutive expression of suppressor of cytokine signalling-3 in skeletal muscle leads to reduced mobility and overweight in mice
    P. Lebrun, Emmanuelle Cognard, Rachel Paul, P. Gontard, Chantal Filloux, Chantal Jehl-Piétri, Paul André Grimaldi, M. Samson, Luc Pénicaud, Jesús Ruberte et al. · 2009 · Diabetologia
27. JAK-STAT signaling and myocardial glucose metabolism
    Miguel A. Frias, Christophe Montessuit · 2013 · JAK-STAT
28. Leber congenital amaurosis, from darkness to light: An ode to Irene Maumenee
    Razek Georges Coussa, Irma López, Robert K. Koenekoop · 2017 · Ophthalmic Genetics
29. The Suppressor of Cytokine Signalling 3, SOCS3, may be One Critical Modulator of Seasonal Body Weight Changes in the Siberian Hamster, Phodopus sungorus
    Alexander Tups, Perry Barrett, Alexander Ross, Peter J. Morgan, Martin Klingenspor, Julian G. Mercer · 2005 · Journal of Neuroendocrinology
30. Suppressors of cytokine signaling (SOCS) and type 2 diabetes
    Xiaotao Feng, Hongzhen Tang, Jing Leng, Qiuyan Jiang · 2014 · Molecular Biology Reports
31. The expression of suppressor of cytokine signaling 1 and 3 in fat and placental tissue from women with gestational diabetes
    Mariusz Kuźmicki, Beata Telejko, Natalia Wawrusiewicz‐Kurylonek, Anna Citko, Danuta Lipińska, Justyna Pliszka, Juliusz Wilk, Katarzyna Kalejta, Adam Lemancewicz, Marek Grabiec et al. · 2012 · Gynecological Endocrinology
32. NAD metabolism in aging and cancer
    John W. R. Kincaid, Nathan A. Berger · 2020 · Experimental Biology and Medicine
33. Crystal Structure of Nicotinic Acid Mononucleotide Adenylyltransferase from Staphyloccocus aureus: Structural Basis for NaAD Interaction in Functional Dimer
    Seungil Han, Michael D. Forman, Pat Loulakis, Michelle H. Rosner, Xie Zhi, Hongfei Wang, Dennis E. Danley, Wei Yuan, John R. Schafer, Zuoyu Xu · 2006 · Journal of Molecular Biology
34. RETRACTED ARTICLE: SOCS3 inhibits insulin signaling in porcine primary adipocytes
    Shuangjuan Yang, Cheng-Quan Xu, Jiang Wei Wu, Gong-She Yang · 2010 · Molecular and Cellular Biochemistry · Retracted
35. YCL047C/POF1 Is a Novel Nicotinamide Mononucleotide Adenylyltransferase (NMNAT) in Saccharomyces cerevisiae
    Michiko Kato, Su-Ju Lin · 2014 · Journal of Biological Chemistry
36. Human homologue of a gene mutated in the slow Wallerian degeneration (C57BL/Wlds) mouse
    F.Shama Fernando, Laura Conforti, Sabrina Tosi, A. David Smith, Michael P. Coleman · 2002 · Gene
37. WldS, Nmnats and axon degeneration-progress in the past two decades
    Yan Feng, Tingting Yan, Zhigang He, Qiwei Zhai · 2010 · Protein & Cell
38. Short‐term tamoxifen treatment has long‐term effects on metabolism in high‐fat diet‐fed mice with involvement of Nmnat2 in POMC neurons
    Zhiyuan Liu, Yalan Cheng, Yi Luan, Wuling Zhong, Hejin Lai, Hui Wang, Huimin Yu, Yale Yang, Ning Feng, Feixiang Yuan et al. · 2018 · FEBS Letters
39. Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells
    M. Di Stefano, Lucia Galassi, Giulio Magni · 2010 · Blood Cells Molecules and Diseases
40. NAD metabolism and heart failure: Mechanisms and therapeutic potentials
    Matthew A. Walker, Rong Tian · 2024 · Journal of Molecular and Cellular Cardiology
41. Nicotinamide mononucleotide adenylyltransferase2 overexpression enhances colorectal cancer cell-kill by Tiazofurin
    Praveen Kusumanchi, Y. Zhang, Marghi Jani, Nagesh H. Jayaram, Rehana A. Khan, Ying-Sheng Tang, Asok C. Antony, Hiremagalur N. Jayaram · 2013 · Cancer Gene Therapy
42. Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: New insights on structure and function relationship
    Lucia Brunetti, M. Di Stefano, Silverio Ruggieri, Flavio Cimadamore, Giulio Magni · 2010 · Protein Science
43. Pathobiochemistry of Aging and Neurodegeneration: Deregulation of NAD+ Metabolism in Brain Cells
    Nataliya A. Kolotyeva, Alexander A. Groshkov, Natalia A. Rozanova, Arseniy K. Berdnikov, Svetlana V. Novikova, Yulia K. Komleva, Alla Borisovna Salmina, Sergey Nikolaevich Illarioshkin, М. А. Пирадов · 2024 · Biomolecules
44. 4-Hydroxyisoleucine attenuates the inflammation-mediated insulin resistance by the activation of AMPK and suppression of SOCS-3 coimmunoprecipitation with both the IR-β subunit as well as IRS-1
    Sudeep Gautam, Nayab Ishrat, Pragya Dhruv Yadav, Rohit Man Singh, Tadigoppula Narender, Arvind Kumar Srivastava · 2016 · Molecular and Cellular Biochemistry
45. Benefits of Enhancing Nicotinamide Adenine Dinucleotide Levels in Damaged or Diseased Nerve Cells
    Andrew A. Pieper, Steven Lanier McKnight · 2018 · Cold Spring Harbor Symposia on Quantitative Biology
46. Role of cardiotrophin-1 in obesity and insulin resistance
    María Jesús Moreno-Aliaga, María Asunción Romero‐Lozano, David Castaño, Jesús Prìeto, Matilde Bustos · 2012 · Adipocyte
47. Mutational, Structural, and Kinetic Studies of the ATP-binding Site of Methanobacterium thermoautotrophicum Nicotinamide Mononucleotide Adenylyltransferase
    V. Saridakis, Emil F. PAI · 2003 · Journal of Biological Chemistry
48. Influence of the DASH diet and other low-fat, high-carbohydrate diets on blood pressure
    Delichatsios, Helen K., Welty, Francine K. · 2005 · Current Atherosclerosis Reports
49. Induction of SOCS-3 is insufficient to confer IRS-1 protein degradation in 3T3-L1 adipocytes
    Fang He, Jacqueline M. Stephens · 2006 · Biochemical and Biophysical Research Communications
50. Insulin Is an Anti-inflammatory and Anti-atherosclerotic Hormone
    Paresh Dandona, Ahmad Aljada, Amy O’Donnell, Sandeep Dhindsa, Rajesh Garg · 2004 · Metabolic Syndrome and Related Disorders
51. NMNAT1 and hereditary spastic paraplegia (HSP): expanding the phenotypic spectrum of NMNAT1 variants
    Zahra Sadr, Aida Ghasemi, Mohammad Rohani, Afagh Alavi · 2023 · Neuromuscular Disorders
52. UBE4B: A Promising Regulatory Molecule in Neuronal Death and Survival
    Rami Abou Zeinab, Hong Wu, Consolato Maria Sergi, Roger P. Leng · 2012 · International Journal of Molecular Sciences
53. Development of low blood glucose readings in nine non-diabetic patients treated with tumor necrosis factor-alpha inhibitors: a case series
    Jadwiga B Czajkowska, Brandon G. Shutty, Susan Zito · 2012 · Journal of Medical Case Reports
54. Hepatic NMNAT1 is required to defend against alcohol-associated fatty liver disease
    Qinchao Ding, Feiwei Cao, Hui Zhuge, Shanglei Lai, Wenjing Cao, Haibin Wei, Rui Guo, Jiannan Qiu, Qing Song, Liuhua Pei et al. · 2025 · Science Advances
55. Decrease in ATP biosynthesis and dysfunction of biological membranes. Two possible key mechanisms of phenoptosis
    A. V. Rzheshevsky · 2014 · Biochemistry (Moscow)
56. Structural and Functional Characterization of Plasmodium falciparum Nicotinic Acid Mononucleotide Adenylyltransferase
    Jochen Bathke, Karin Fritz‐Wolf, Christina Brandstädter, Anja Burkhardt, Esther Jortzik, Stefan Rahlfs, Katja Becker · 2016 · Journal of Molecular Biology
57. Formation of [Nicotinamide-2H3]NAD+ from [2H4]Nicotinamide and [2H4]Nicotinic Acid in Human HepG2N Cells and Involvement of 2H/1H Exchange at the Redox Site of NAD+/NADH
    Nobumasa Hara, Tomoko Shibata, Harumi Osago, Kazuo Yamada, Mikako Tsuchiya · 2014 · Journal of Nutritional Science and Vitaminology
58. Lack of nicotinamide mononucleotide adenylyltransferase 2 ( N mnat2): Consequences for mouse bladder development and function
    Amy N. Hicks, Lysanne Campeau, David Mark Burmeister, Colin E. Bishop, Karl‐Erik Andersson · 2013 · Neurourology and Urodynamics
59. From obesity through immunity to type 2 diabetes mellitus
    Leszek Szablewski · 2016 · International Journal of Diabetes in Developing Countries
60. Aerobic training reverses high-fat diet-induced pro-inflammatory signalling in rat skeletal muscle
    Ben B. Yaspelkis, Ilya A. Kvasha, Sarah J. Lessard, Donato Americo Rivas, John Alan Hawley · 2010 · European Journal of Applied Physiology
61. Different Transcription Profiles of SOCS-3, ob and IGF-I Genes and their Possible Correlations in Obese and Lean Pigs
    Jiang Wei Wu, Bo Wang, Haowei Zhang, Taiyong Yu, Gongshe Yang · 2007 · Acta Biochimica et Biophysica Sinica
62. Effect of Feeding with a Poisonous Mushroom Clitocybe acromelalga on the Metabolism of Tryptophan-Niacin in Rats.
    Tsutomu Fukuwatari, Etsuro SUGIMOTO, Katsumi Shibata · 2001 · Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)
63. Response of the Lung to Pulmonary Insulin Dosing in the Rat Model and Effects of Changes in Formulation
    T. Cooper Woods, Bin Zhang, Frank Mercogliano, Steven M. Dinh · 2005 · Diabetes Technology & Therapeutics
64. Retinol Binding Protein 4: Role in Diabetes and Cancer
    Daniel C. Berry, Noa Noy · 2016 · Energy balance and cancer
65. Dinucleoside Polyphosphate NAD Analogs as Potential NMN Adenylyltransferase Inhibitors. Synthesis and Biological Evaluation
    Palmarisa Franchetti, Loredana Cappellacci, Michela Pasqualini, Mario Grifantini, Teresa Lorenzi, Nadia Raffaelli, Giulio Magni · 2003 · Nucleosides Nucleotides & Nucleic Acids
66. Imaging the uptake and metabolism of glutamine in prostate tumor models using CEST MRI
    Yuki Hodo, Caitlin M. Tressler, Behnaz Ghaemi, Rebecca L. Thomas, Aliyah S. Webster, Kirsten N. Bains Williams, Yuguo Li, Martin G. Pomper, Chi Van Dang, Zaver M. Bhujwalla et al. · 2025 · npj Imaging
67. Regulation of hepatic insulin sensitivity by activating signal co-integrator-2
    Geun Hyang Kim, Kyung Jin Lee, Gyun‐Sik Oh, Jin Ho Yoon, Hae Won Kim, Seung‐Whan Kim · 2012 · Biochemical Journal
68. Obtaining high yield recombinant Enterococcus faecium nicotinate nucleotide adenylyltransferase for X-ray crystallography and biophysical studies
    Olamide Jeje, Ramesh Pandian, Yasien Sayed, Ikechukwu Achilonu · 2023 · International Journal of Biological Macromolecules
69. Reactive oxygen species up-regulates SOCS-3 in 3T3-L1 adipocytes
    Yu Ruan, Fenping Zheng, Lin Li, Zhou Wang, Hong Li · 2014 · International Journal of Diabetes in Developing Countries
70. Nicotinamide mononucleotide adenylyltransferase displays alternate binding modes for nicotinamide nucleotides
    Roland Pfoh, Emil F. PAI, V. Saridakis · 2015 · Acta Crystallographica Section D Biological Crystallography
71. Nicotinamide adenine dinucleotide+ metabolism biomarkers in malignant gliomas
    Antonio Lucena-Cacace, Manuel P. Jiménez-García, EvaM Verdugo-Sivianes · 2016 · Cancer translational medicine
72. Crystallization and preliminary X-ray analysis of human nicotinamide mononucleotide adenylyltransferase (NMNAT)
    Erik Werner, Mathias Ziegler, Felicitas Lerner, Manfred Schweiger, Yves A. Muller, Udo Heinemann · 2001 · Acta Crystallographica Section D Biological Crystallography
73. Structural insights into Plasmodium falciparum nicotinamide mononucleotide adenylyltransferase: oligomeric assembly
    Luis Ernesto Contreras-Rodríguez, Catherin Yizet Marin-Mogollon, Lina Marcela Sánchez-Mejía, María Helena Ramírez-Hernández · 2018 · Memórias do Instituto Oswaldo Cruz
74. A Yeast Expression System of High Efficiency for Producing Recombinant Enzymes
    Cyrus B. Munshi, Hon Cheung Lee · 2002 · Springer eBooks
75. In silico screening of candidate NAMPT modulators for treatment of age-related diseases
    Jarmila Nahálková, Fernando Berton Zanchi · 2026 · In Silico Research in Biomedicine
76. Pseudocoloboma-like maculopathy with biallelicRDH12missense mutations
    Che‐Yuan Kuo, Ming‐Yi Chung, Shih‐Jen Chen · 2023 · Journal of Medical Genetics
77. Functional Characterisation of Three Human Nicotinamide Mononucleotide Adenylyltransferases
    Corinna Lau · 2008 · NORA - Norwegian Open Research Archives
78. Niacin
    Christelle Bourgeois · 2010 · CRC Press eBooks
79. Etude de la biosynthese du nad chez les plantes : conséquences physiologiques de sa manipulation chez Arabidopsis thaliana
    Pierre Pétriacq · 2011
80. NicotinamideMononucleotideAdenylyltransferase ExpressioninMitochondrialMatrixDelaysWallerian Degeneration
    Toshiyuki Araki · 2009
81. Dissecting Key Cellular Players Regulating Pathophysiology of Acute and Chronic Allergic Asthma
    Ena Ray Banerjee · 2016 · Springer eBooks
82. Deletion of Sarm1 gene protects against paclitaxel-induced and type II diabetic peripheral neuropathies
    Elliot Turkiew · 2015
83. NAD + Modulation
    Elena Katsyuba, Johan H. Auwerx · 2018 · Elsevier eBooks
84. Nicotinamide-nucleotide adenylyltransferase
    2007 · Springer eBooks
85. In silico screening of candidate NAMPT modulators for treatment of age-related diseases
    Jarmila Nahálková, Fernando Berton Zanchi · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
86. Structure et Mécanisme de la Quinolinate Synthase : enzyme à centre [4Fe-4S]2+ et cible d'agents antibactériens
    Alice Chan · 2014
87. Pyrimidine and NAD salvage pathways : unexpected allies in the maintenance of genome stability
    Sandra Cunha Silveira · 2018 · theses.fr (ABES)
88. The Pof1 nicotinamide mononucleotide adenylyl transferase has a non-canonical role in NAD+ metabolism in the budding yeast Saccharomyces cerevisiae
    Yi‐Ching Lee, Chi-Chun Huang, Matilda McDaniel, Katie Huang, Lan-Hsuan Lee, Gordon Lao, Darshan Karthi, Su-Ju Lin · 2026 · Journal of Biological Chemistry