Function of Histone Deacetylase 6 as a Cofactor of Nuclear Receptor Coregulator LCoR

HDAC6 is a microtubule-associated deacetylase

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Nuclear Receptors and Lipid Physiology: Opening the X-Files

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Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators

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Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter

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Genome-wide analysis of estrogen receptor binding sites

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Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase

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A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression

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Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

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Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A

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In vivo destabilization of dynamic microtubules by HDAC6‐mediated deacetylation

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The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors

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Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

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Molecular determinants of nuclear receptor-corepressor interactionPreprint

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Coregulator codes of transcriptional regulation by nuclear receptors

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p300 Transcriptional Repression Is Mediated by SUMO Modification

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HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination

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Genome-Wide Identification of High-Affinity Estrogen Response Elements in Human and Mouse

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Impact of Estrogen Receptor β on Gene Networks Regulated by Estrogen Receptor α in Breast Cancer Cells

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Runx2 (Cbfa1, AML-3) Interacts with Histone Deacetylase 6 and Represses the p21 CIP1/WAF1 Promoter

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HDAC6 Expression Is Correlated with Better Survival in Breast Cancer

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Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway.

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Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer

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Ligand-Dependent Nuclear Receptor Corepressor LCoR Functions by Histone Deacetylase-Dependent and -Independent Mechanisms

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Collaborative spirit of histone deacetylases in regulating chromatin structure and gene expression

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Structural studies on nuclear receptors

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Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm

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Role of Acetylation and Extracellular Location of Heat Shock Protein 90α in Tumor Cell Invasion

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Transcription in four dimensions: nuclear receptor‐directed initiation of gene expression

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Role of the Aggresome Pathway in Cancer: Targeting Histone Deacetylase 6–Dependent Protein Degradation

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Role of the Tetradecapeptide Repeat Domain of Human Histone Deacetylase 6 in Cytoplasmic Retention

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TBL1 and TBLR1 Phosphorylation on Regulated Gene Promoters Overcomes Dual CtBP and NCoR/SMRT Transcriptional Repression Checkpoints

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Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells

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BMP7 influences proliferation, migration, and invasion of breast cancer cells

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Dynamic Acetylation of All Lysine 4–Methylated Histone H3 in the Mouse Nucleus: Analysis at c-fos and c-jun

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ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases

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Clinical Significance of BMP7 in Human Colorectal Cancer

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A shifting paradigm: histone deacetylases and transcriptional activation

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Convergence of vitamin D and retinoic acid signalling at a common hormone response element

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Prediction of prognosis of estrogen receptor‐positive breast cancer with combination of selected estrogen‐regulated genes

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Corepressor Recruitment by Agonist-Bound Nuclear Receptors

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Incorporation of histone deacetylase inhibition into the structure of a nuclear receptor agonist

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Ligand-dependent Corepressor LCoR Is an Attenuator of Progesterone-regulated Gene Expression

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Aggressive melanoma cells escape from BMP7-mediated autocrine growth inhibition through coordinated Noggin upregulation

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Limiting Effects of RIP140 in Estrogen Signaling

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Sequential Recruitment and Combinatorial Assembling of Multiprotein Complexes in Transcriptional Activation

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Selective repression of retinoic acid target genes by RIP140 during induced tumor cell differentiation of pluripotent human embryonal carcinoma cells

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BMP7/ActRIIB regulates estrogen‐dependent apoptosis: New biomarkers for environmental estrogens

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HDAC6-induced premature chromatin compaction in mouse oocytes and fertilised eggs

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Progressive Loss of Estrogen Receptor α Cofactor Recruitment in Endocrine Resistance

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Deconstructing repression: evolving models of co-repressor action

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Retinoic acid receptors: From molecular mechanisms to cancer therapy

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Histone deacetylase 6 plays a role as a distinct regulator of diverse cellular processes

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HDAC6 as privileged target in drug discovery: A perspective

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Tubulin acetylation: responsible enzymes, biological functions and human diseases

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Histone Deacetylase 6 in Health and Disease

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Essential role of HDAC6 in the regulation of PD‐L1 in melanoma

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Modulation of Histone Deacetylase 6 (HDAC6) Nuclear Import and Tubulin Deacetylase Activity through Acetylation

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Development and Therapeutic Implications of Selective Histone Deacetylase 6 Inhibitors

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Epigenetic regulation of estrogen signaling in breast cancer

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A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs

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HDAC6: A unique HDAC family member as a cancer target

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Histone Deacetylase 6 (HDAC6) Is an Essential Modifier of Glucocorticoid-Induced Hepatic Gluconeogenesis

Winkler, R., Benz, V., Clemenz, M., Bloch, M., Foryst‐Ludwig, A., Wardat, S., Witte, N., Trappiel, M., Namsolleck, P., Mai, K., et al. (2011) · Diabetes · doi:10.2337/db11-0313 · Cited by 92 · see citing works

Epigenetics of Estrogen Receptor Signaling: Role in Hormonal Cancer Progression and Therapy

Mann, M., Cortez, V. A., & Vadlamudi, R. K. (2011) · Cancers · doi:10.3390/cancers3021691 · Cited by 92 · see citing works

Histone deacetylase 6 regulates the immunosuppressive properties of cancer-associated fibroblasts in breast cancer through the STAT3–COX2-dependent pathway

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The therapeutic hope for HDAC6 inhibitors in malignancy and chronic disease

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Nuclear receptor coregulators as a new paradigm for therapeutic targeting

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A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth

Kaliszczak, M., Trousil, S., Åberg, O., Perumal, M., Nguyen, Q.-D., & Aboagye, E. O. (2013) · British Journal of Cancer · doi:10.1038/bjc.2012.576 · Cited by 66 · see citing works

HDAC6 as a target for antileukemic drugs in acute myeloid leukemia

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Histone Deacetylase 6 Represents a Novel Drug Target in the Oncogenic Hedgehog Signaling Pathway

Dhanyamraju, P. K., Holz, P. S., Finkernagel, F., Fendrich, V., & Lauth, M. (2014) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-14-0481 · Cited by 50 · see citing works

HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth

Medler, T. R., Craig, J. M., Fiorillo, A. A., Feeney, Y. B., Harrell, J. C., & Clevenger, C. V. (2016) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-16-0109 · Cited by 52 · see citing works

Comparison of the Deacylase and Deacetylase Activity of Zinc-Dependent HDACs

McClure, J. J., Inks, E. S., Zhang, C., Peterson, Y. K., Li, J., Chundru, K. J., Lee, B., Buchanan, A., Miao, S., & Chou, C. J. (2017) · ACS Chemical Biology · doi:10.1021/acschembio.7b00321 · Cited by 51 · see citing works

NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model

Liu, Y., Li, Y., Liu, S., Adeegbe, D. O., Christensen, C. L., Quinn, M. M., Dries, R., Han, S., Buczkowski, K. A., Wang, X., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-18-0161 · Cited by 50 · see citing works

Ligand-dependent Corepressor LCoR Is an Attenuator of Progesterone-regulated Gene Expression

Palijan, A., Fernandes, I., Verway, M. J., Kourelis, M., Bastien, Y., Tavera-Mendoza, L. E., Sacheli, A., Bourdeau, V., Mader, S., & White, J. H. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.051201 · Cited by 48 · see citing works

Ligand-dependent Corepressor (LCoR) Recruitment by Krüppel-like Factor 6 (KLF6) Regulates Expression of the Cyclin-dependent Kinase Inhibitor CDKN1A Gene

Calderon, M. R., Verway, M. J., An, B., DiFeo, A. V., Bismar, T. A., Ann, D. K., Martignetti, J. A., Shalom‐Barak, T., & White, J. H. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.311605 · Cited by 42 · see citing works

Selective Histonedeacetylase Inhibitor M344 Intervenes in HIV-1 Latency through Increasing Histone Acetylation and Activation of NF-kappaB

Ying, H., Zhang, Y., Zhou, X., Qu, X., Wang, P., Liu, S., Lu, D., & Zhu, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048832 · Cited by 37 · see citing works

Ligand-dependent corepressor acts as a novel corepressor of thyroid hormone receptor and represses hepatic lipogenesis in mice

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Epigenetic Regulation by Nuclear Receptors

Green, C. D., & Han, J. J. (2011) · Epigenomics · doi:10.2217/epi.10.75 · Cited by 33 · see citing works

Complex regulation of LCoR signaling in breast cancer cells

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HDAC6 and Ovarian Cancer

Haakenson, J., & Zhang, X. M. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms14059514 · Cited by 30 · see citing works

Differential exosomal microRNA profile in the serum of a patient with depression

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Nuclear Receptor Coregulators in Hormone-Dependent Cancers

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TNIP1 is a corepressor of agonist-bound PPARs

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