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Dual Role of α-Secretase Cleavage in the Regulation of γ-Secretase Activity for Amyloid Production
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C83 inhibits Aβ generation by interfering with C99 processing by γ-secretase in HEK cells.
“C83) can also inhibit Aβ generation by interfering with C99 processing by γ-secretase in HEK cells (Tian et al., 2010)”
From Emerging Alternative Proteinases in APP Metabolism and Alzheimer’s Disease Pathogenesis: A Focus on MT1-MMP and MT5-MMP (2019) · cites this paper as Tian et al., 2010
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Amyloid deposition as the central event in the aetiology of Alzheimer’s disease
Hardy, J., & Allsop, D. (1991) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(91)90609-v · Cited by 2,538
Shen, J., & Kelleher, R. J. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608332104 · Cited by 485
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Research works printed but not linked: 31
- Brown, 2000, Cell, 100, 391, 10.1016/S0092-8674(00)80675-3 · DOI · Paper page
- Urban, 2001, Cell, 107, 173, 10.1016/S0092-8674(01)00525-6 · DOI
- McQuibban, 2003, Nature, 423, 537, 10.1038/nature01633 · DOI
- Cipolat, 2006, Cell, 126, 163, 10.1016/j.cell.2006.06.021 · DOI
- Shah, 2005, Cell, 122, 435, 10.1016/j.cell.2005.05.022 · DOI
- Dries, 2009, J. Biol. Chem., 284, 29714, 10.1074/jbc.M109.038737 · DOI
- Chávez-Gutiérrez, 2008, J. Biol. Chem., 283, 20096, 10.1074/jbc.M803040200 · DOI
- Zhao, 2010, J. Neurosci., 30, 1648, 10.1523/JNEUROSCI.3826-09.2010 · DOI
- Nitsch, 1992, Science, 258, 304, 10.1126/science.1411529 · DOI · Paper page
- Skovronsky, 2000, J. Biol. Chem., 275, 2568, 10.1074/jbc.275.4.2568 · DOI
- Lammich, 1999, Proc. Natl. Acad. Sci. U.S.A., 96, 3922, 10.1073/pnas.96.7.3922 · DOI · Paper page
- Postina, 2004, J. Clin. Invest., 113, 1456, 10.1172/JCI20864 · DOI · Paper page
- Fahrenholz, 2007, Curr. Alzheimer Res., 4, 412, 10.2174/156720507781788837 · DOI
- Olsson, 2003, Exp. Neurol., 183, 74, 10.1016/S0014-4886(03)00027-X · DOI
- Sennvik, 2000, Neurosci. Lett., 278, 169, 10.1016/S0304-3940(99)00929-5 · DOI
- Tian, 2010, Nat. Struct. Mol. Biol., 17, 151, 10.1038/nsmb.1743 · DOI
- McCafferty, 1997, Biochemistry, 36, 10498, 10.1021/bi970543u · DOI
- Li, 2000, Proc. Natl. Acad. Sci. U.S.A., 97, 6138, 10.1073/pnas.110126897 · DOI
- Yin, 2007, J. Biol. Chem., 282, 23639, 10.1074/jbc.M704601200 · DOI
- Kojro, 2005, Subcell. Biochem., 38, 105, 10.1007/0-387-23226-5_5 · DOI
- Buxbaum, 1998, J. Biol. Chem., 273, 27765, 10.1074/jbc.273.43.27765 · DOI
- Shearman, 2000, Biochemistry, 39, 8698, 10.1021/bi0005456 · DOI
- Thinakaran, 2008, J. Biol. Chem., 283, 29615, 10.1074/jbc.R800019200 · DOI · Paper page
- Esler, 2002, Proc. Natl. Acad. Sci. U.S.A., 99, 2720, 10.1073/pnas.052436599 · DOI
- Shelton, 2009, Assay Drug Dev. Technol., 7, 461, 10.1089/adt.2009.0202 · DOI
- Shelton, 2009, Mol. Neurodegener., 4, 22, 10.1186/1750-1326-4-22 · DOI
- Shelton, 2009, Proc. Natl. Acad. Sci. U.S.A., 106, 20228, 10.1073/pnas.0910757106 · DOI
- Placanica, 2009, PLoS ONE, 4, e5088, 10.1371/journal.pone.0005088 · DOI
- Placanica, 2010, Biochemistry, 49, 2796, 10.1021/bi901388t · DOI
- Lannfelt, 1995, Nat. Med., 1, 829, 10.1038/nm0895-829 · DOI
- Tyler, 2002, Biochem. Biophys. Res. Commun., 299, 373, 10.1016/S0006-291X(02)02635-9 · DOI
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The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease
Hur, J.-Y., Frost, G. R., Wu, X., Crump, C., Pan, S. J., Wong, E., Barros, M., Li, T., Nie, P., Zhai, Y., et al. (2020) · Nature · doi:10.1038/s41586-020-2681-2 · Cited by 382
Self-citationGarcía-González, L., Pilat, D., Baranger, K., & Rivera, S. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00244 · Cited by 88
Spilman, P. R., Corset, V., Gorostiza, O., Poksay, K. S., Galvan, V., Zhang, J., Rao, R., Peters-Libeu, C., Vincelette, J., McGeehan, A., et al. (2016) · Journal of Alzheimer's Disease · doi:10.3233/jad-151046 · Cited by 39
Metadata
- Authors
- Tian, Y., Crump, C. J., & Li, Y.-M.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2010-10
- Volume
- 285
- Issue
- 42
- Pages
- 32549-32556
- ISSN
- 0021-9258
- Cited by
- 42
- References
- 2
- Language
- en
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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