Identification and Characterization of a Sphingolipid Δ4-Desaturase Family

Cited by (292)

Items 201–292 of 292

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2. Neuronal Ganglioside and Glycosphingolipid (GSL) Metabolism and Disease
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3. Identification of a cytochrome b5-fusion desaturase responsible for the synthesis of triunsaturated sphingolipid long chain bases in the marine diatom Thalassiosira pseudonana
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4. Clinical application of C18 and C20 chain length polyunsaturated fatty acids and their biotechnological production in plants
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5. The combination elexacaftor/tezacaftor/ivacaftor (ETI) modulates the de novo synthethic pathway of ceramides in a genotype-independent manner
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6. Characterization of a neutral ceramidase orthologue fromAspergillus oryzae
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7. A Novel Predicted Bromodomain-Related Protein Affects Coordination Between Meiosis and Spermiogenesis in Drosophila and Is Required for Male Meiotic Cytokinesis
   Laura M. Bergner, F. Edward Hickman, Kathleen H. Wood, Carolyn M. Wakeman, Hunter H. Stone, Tessa J. Campbell, Samantha B Lightcap, Sheena M. Favors, Amanda C. Aldridge, Karen G. Hales · 2010 · DNA and Cell Biology
8. Phylogenomic analysis of integral diiron membrane histidine motif-containing enzymes in ciliates provides insights into their function and evolutionary relationships
   Nicolás G. Cid, María L. Sánchez Granel, María Guadalupe Montes, María E. Elguero, Clara B. Nudel, Alejandro David Nusblat · 2017 · Molecular Phylogenetics and Evolution
9. A Candidate Gene Study for the Association of Host Single Nucleotide Polymorphisms with Liver Cirrhosis Risk in Chinese Hepatitis B Patients
   Lijun Peng, Guo J, Zhe Zhang, Lili Liu, Yirong Cao, Hong Shi, Jian Wang, Jiyao Wang, Scott L. Friedman, John J. Sninsky · 2013 · Genetic Testing and Molecular Biomarkers
10. Structure–function studies of yeast C-4 sphingolipid long chain base hydroxylase
    Jolanta Idkowiak‐Baldys, Jon Y. Takemoto, Michelle M. Grilley · 2003 · Biochimica et Biophysica Acta (BBA) - Biomembranes
11. Sphingolipid base modifying enzymes in sunflower (Helianthus annuus): Cloning and characterization of a C4-hydroxylase gene and a new paralogous Δ8-desaturase gene
    Antonio J. Moreno‐Pérez, Enrique Martínez‐Force, Rafael Garcés, Joaquín Jesús Salas · 2011 · Journal of Plant Physiology
12. Sphingolipids: Less Enigmatic but Still Many Questions about the Role(s) of Ceramide in the Synthesis/Function of the Ganglioside Class of Glycosphingolipids
    Cara‐Lynne Schengrund · 2024 · International Journal of Molecular Sciences
13. Evaluation of reference genes for gene expression analysis in Japanese flounder (Paralichthys olivaceus) under temperature stress
    Ping Han, Jianming Chen, Zhennan Sun, Shengjie Ren, Xubo Wang · 2025 · BMC Genomics
14. Genome‐wide comparative identification and analysis of membrane‐FADS ‐like superfamily genes in freshwater economic fishes
    Yuru Zhang, Junmei Zhang, Kedi Gao, Ronghua Lu, Xianglin Cao, Liping Yang, Guoxing Nie · 2023 · FEBS Open Bio
15. Arabidopsis Leaf Chloroplasts Have a Specific Sphingolipidome
    Chang Yang, Lingyan Wang, Yongkang Li, Jia‐Ting Lin, Ding‐Kang Chen, Nan Yao · 2024 · Plants
16. The Sphinx and the egg: Evolutionary enigmas of the (glyco)sphingolipid biosynthetic pathway
    Assaf Biran, Tânia C.B. Santos, Tamir Dingjan, Anthony H. Futerman · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
17. Characterization of bifunctional sphingolipid Δ4-desaturases/C4-hydroxylases of trypanosomatids by liquid chromatography–electrospray tandem mass spectrometry
    Paola Vacchina, Karina E. J. Trípodi, Andréa M. Escalante, Antonio D. Uttaro · 2012 · Molecular and Biochemical Parasitology
18. Identification of Plant Sphingolipid Desaturases Using Chromatography and Mass Spectrometry
    Dayong Sun, Byron E. Froman, Robert G. Orth, Susan MacIsaac, Thomas Larosa, F. Dong, Henry E. Valentin · 2009 · Journal of Chromatographic Science
19. Sphingolipid Metabolism and Leukemia: A Potential for Novel Therapeutic Approaches
    Tara Ann Burns, Chiara Luberto · 2011 · Anti-Cancer Agents in Medicinal Chemistry
20. Barrier lipid composition and response to plasma lipids: A direct comparison of mouse dorsal back and ear skin
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21. Synthesis of Structural and Storage Lipids by the ER
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22. Simultaneous production of sphingolipids and ethanol byKluyveromyces thermotolerans
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23. Sphingolipid synthesis maintains nuclear membrane integrity and genome stability during cell division
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24. Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of Jak1
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25. Unsaturated Fatty Acids
    Peter H. Buist · 2010 · Elsevier eBooks
26. Decreases in 15-lipoxygenase metabolites in Olmsted syndrome model rats
    Masato Wakabayashi, Takeshi Yoshioka, Kenichi Higashino, Yoshito Numata, Yasuyuki Igarashi, Akio Kihara · 2016 · Journal of Dermatological Science
27. 11 Plant sphingolipids
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28. Bioactive Compounds Targeting Dihydroceramide and Their Therapeutic Potential in Cancer Treatment
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29. Cardiomyocytes, sphingolipids and cardio myotoxicity
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30. Sphingolipid Δ4-desaturation is an important metabolic step for glycosylceramide formation in Physcomitrium patens
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31. Insights into membrane-bound fatty acid desaturase genes in tigernut (Cyperus esculentus L.), an oil-rich tuber plant in Cyperaceae
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32. Dihydroceramide Desaturase Inhibition by a Cyclopropanated Dihydroceramide Analog in Cultured Keratinocytes
    Susanne Brodesser, Thomas Kolter · 2010 · Journal of Lipids
33. Tools for the analysis of metabolic flux through the sphingolipid pathway
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34. Regulation mechanism of lipids for extracellular yellow pigments production by Monascus purpureus BWY-5
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35. Systemic and heart autonomous effects of sphingosine Δ-4 desaturase deficiency in lipotoxic cardiac pathophysiology
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36. A novel Tetrahymena thermophila sterol C-22 desaturase belongs to the fatty acid hydroxylase/desaturase superfamily
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37. Relationship between time-dependent epidermal ceramide composition changes and skin barrier function in adult mice
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38. Acyl‐CoA:wax alcohol acyltransferase 2 modulates the cone visual cycle in mouse retina
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39. Occurrence of ceramides in the Acidobacterium Solibacter usitatus: implications for bacterial physiology and sphingolipids in soils
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40. Glycosphingolipids: from metabolism to chemoenzymatic total synthesis
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41. Harnessing the power of yeast to elucidate the role of sphingolipids in metabolic and signaling processes pertinent to psychiatric disorders
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42. Bioactive Sphingolipids in Neuroblastoma
    Mehrdad Rahmaniyan, Amr Qudeimat, M. Jacqueline · 2012 · InTech eBooks
43. Hypoxia remodels the composition of the constituent ceramide species of HexCer and Hex2Cer with phytosphingosine and hydroxy fatty acids in human colon cancer LS174T cells
    Kouji Tanaka, Keiko Tamiya‐Koizumi, Masaki Yamada, Takashi Murate, Reiji Kannagi, Mamoru Kyogashima · 2015 · Glycoconjugate Journal
44. Elucidation of physiological functions of sphingolipid-related molecules by chemical approaches
    Yuta Murai · 2024 · Bioscience Biotechnology and Biochemistry
45. Transcriptome comparison of dengue-susceptible and -resistant field derived strains of Colombian Aedes aegypti using RNA-sequencing
    Heather G. Coatsworth, Paola A. Caicedo, Geoffrey L. Winsor, Fiona S. L. Brinkman, Clara Beatriz Ocampo, Carl A. Lowenberger · 2021 · Memórias do Instituto Oswaldo Cruz
46. Sphingolipids: From structural components to signaling hubs
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47. Characterization of Unique Eukaryotic Sphingolipids with Temperature-Dependent Δ8-Unsaturation from the Picoalga Ostreococcus tauri
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48. WITHDRAWN: Mammalian sphingoid bases: Biophysical, physiological and pathological properties
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49. Genome-Wide Identification, Phylogenetic and Expression Pattern Analysis of Fatty Acid Desaturase Genes in Castor (Ricinus communis L.)
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50. Polymorphisms of AZIN1 rs2679757 and TRPM5 rs886277 are Associated with Cirrhosis Risk in Chinese Patients with Chronic Hepatitis B
    Lijun Peng, Guo J, Zhe Zhang, Lili Liu, Yirong Cao, Hong Shi, Jian Wang, Scott L. Friedman, John J. Sninsky, Jiyao Wang · 2012 · Infection International/Infection International (Electronic Edition)
51. Sphingolipid metabolism and signaling in plant stress responses and crop improvement
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52. The role of sphingolipids in major depressive disorder and associated cognitive impairment: interactions with monoaminergic signaling, neuroinflammation, and neurogenesis
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53. Genetic Tools for Studying the Roles of Sphingolipids in Viral Infections
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54. Genetic Characterization of the Acidic and Neutral Glycosphingolipid Biosynthetic Pathways in Neurospora crassa
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55. Functional characterization of a plastidial cytochrome b5-fused Δ4-desaturase from Ostreococcus tauri in higher plants
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56. SPHINGOLIPID VARIETY, BIOSYNTHESIS AND REGULATION
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57. Lipid Metabolism in Model Fungi: The Achilles Heel of Fungal Pathogens
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58. Structure and function of mammalian sphingolipids in health and disease
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59. Sphingolipid Metabolism via Sphingosine 1-Phosphate and Its Role in Physiology, Pathology, and Nutrition
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60. Analysis of the Effects of Brefeldin A on Deuterium-Labeled Sphinganine Metabolism Using Liquid Chromatography–Tandem Mass Spectrometry
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61. Emerging roles of lipids in nuclear function and homeostasis
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62. Evolutionary patterns and repeated adaptive strategies of deep-sea anemones
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63. Genome‐Scale CRISPR/Cas9 Screening Reveals Squalene Epoxidase as a Susceptibility Factor for Cytotoxicity of Malformin A1
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65. In-silico characterization of Δ4 and Δ5 desaturases in Symbiodinium microadriaticum and Perkinsus marinus, symbiont and parasitic organisms’ similarities
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66. A novel splice site variant in DEGS1 leads to aberrant splicing and loss of DEGS1 enzyme activity, a VUS resolved
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67. Deletion Testing of the DEGS1 Gene Should Be Part of the Diagnostic Pipeline for Hypomyelinating Leukodystrophy (HLD18)
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68. Synthesis, Metabolism, and Trans-Bilayer Movement of Long-Chain Base
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69. SPTLC1 variants associated with childhood onset amyotrophic lateral sclerosis produce distinct sphingolipid signatures through impaired interaction with ORMDL proteins
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72. Métabolisme et intérêt nutritionnel de l’acide docosapentaénoïque n-3 : modulation du statut tissulaire en acides gras n-3 par les lipides laitiers alimentaires chez le rat
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73. Oncology Drug Targets in the Sphingomyelin-Signaling Pathway
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74. Metabolism and physiological functions of sphingolipids
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75. Sphingolipid Asymmetry and Transmembrane Translocation in Mammalian Cells
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76. Ceramide: Cell Regulation from a Lipid Perspective
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77. Biochemische und molekulare Evidenz für die Beteiligung einer ∆4-Desaturase an der Biosynthese von Docosahexaensäure in Mikroorganismen
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78. Application of liquid chromatography tandem mass spectrometry for the separation and quantitative analysis of sphingolipids.
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79. Genome Wide Analysis Identifies Sphingolipid Metabolism As A New Target Of Valproic Acid
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80. Dihydroceramide: Sphinganine Δ4-Desaturase and C4-Hydroxylase
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81. Understanding the Impact of Low Temperatures in Maize Seed Germination
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82. Sphingoid Bases and -1-Phosphates in Plants: Functional Diversity of
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83. Molecular Mechanism of Skin Permeability Barrier Formation by Ceramides
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84. New sphingolipid probes for metabolism and trafficking studies
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85. Etude structurale des modifications de la glycosylation des macrophages induites par Mycobacterium bovis BCG
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86. Caractérisation d’une signature sphingolipidique d’immunoéchappement dans le cancer du sein triple négatif
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87. Rôle des sphingolipides hépatiques dans la physiopathologie du diabète de type 2
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88. Antitumor potential of anti-glycosphingolipid therapy
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89. Sphingolipid Metabolism in Bone Homeostasis: From Mechanisms and Functional Insights to Clinical Implications
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90. Ceramide Metabolic Pathways and Their Regulation in Adolescent Acne Vulgaris
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91. Functional Characterization and Application of Yarrowia lipolytica YlYxc1 for Enhanced Production of Sphingoid Bases
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92. Sterol Glucosides and Ceramide Glucosides: Cloning of Enzymes Contributing to Their Biosynthesis
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