The Stable Isotope-based Dynamic Metabolic Profile of Butyrate-induced HT29 Cell Differentiation

Methods of Enzymatic Analysis

(1975) · Journal of AOAC INTERNATIONAL · doi:10.1093/jaoac/58.5.1085 · Cited by 20,078 · see citing works

Methods of Enzymatic Analysis

(1974) · Elsevier eBooks · doi:10.1016/b978-0-12-091304-6.x5001-0 · Cited by 6,786 · see citing works

Utilization of Nutrients by Isolated Epithelial Cells of the Rat Colon

Roediger, W. E. W. (1982) · Gastroenterology · doi:10.1016/s0016-5085(82)80339-9 · Cited by 1,201 · see citing works

Histone Deacetylase Inhibitors: Inducers of Differentiation or Apoptosis of Transformed Cells

Marks, P. A., Richon, V. M., & Rifkind, R. A. (2000) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/92.15.1210 · Cited by 1,152 · see citing works

Oncogenic alterations of metabolism

Dang, C. V., & Semenza, G. L. (1999) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(98)01344-9 · Cited by 1,106 · see citing works

Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate.

Augeron, C., & LABOISSE, C. L. (1984) · PubMed · Cited by 539 · see citing works

Pathways of acetate, propionate, and butyrate formation by the human fecal microbial flora

Miller, T. L., & Wolin, M. J. (1996) · Applied and Environmental Microbiology · doi:10.1128/aem.62.5.1589-1592.1996 · Cited by 481 · see citing works

Metabolic control analysis in drug discovery and disease

Cascante, M., Boros, L. G., Comı́n-Anduix, B., de Atauri, P., Centelles, J. J., & Lee, P. W. N. (2002) · Nature Biotechnology · doi:10.1038/nbt0302-243 · Cited by 281 · see citing works

Butyrate Suppression of Colonocyte NF-κB Activation and Cellular Proteasome Activity

Yin, L., Laevsky, G. S., & Giardina, C. A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105170200 · Cited by 267 · see citing works

Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways

Witt, O., Sand, K., & Pekrun, A. (2000) · Blood · doi:10.1182/blood.v95.7.2391.007k21_2391_2396 · Cited by 192 · see citing works

Glutamine transport by the blood-brain barrier: a possible mechanism for nitrogen removal

Lee, W.-J., Hawkins, R. A., Viña, J. R., & Peterson, D. R. (1998) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1998.274.4.c1101 · Cited by 191 · see citing works

Butyrate and glucose metabolism by colonocytes in experimental colitis in mice

Ahmad, M. S., Krishnan, S., Ramakrishna, B., Mathan, M. M., Pulimood, A. B., & Murthy, S. N. (2000) · Gut · doi:10.1136/gut.46.4.493 · Cited by 186 · see citing works

Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways

Witt, O., Sand, K., & Pekrun, A. (2000) · Blood · doi:10.1182/blood.v95.7.2391 · Cited by 184 · see citing works

Genes modulated by histone acetylation as new effectors of butyrate activity

Ragione, F. D., Criniti, V., Pietra, V. D., Borriello, A., Oliva, A., Indaco, S., Yamamoto, T., & Zappia, V. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02539-x · Cited by 148 · see citing works

Studies of Glycogen Synthesis and the Krebs Cycle by Mass Isotopomer Analysis with [U-13C]Glucose in Rats

Katz, J. J., Lee, W. N., Wals, P. A., & Bergner, E. A. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)51586-6 · Cited by 110 · see citing works

Evidence of a functional role for the cyclin-dependent kinase-inhibitor p21WAF1/CIP1/MDA6 in promoting differentiation and preventing mitochondrial dysfunction and apoptosis induced by sodium butyrate in human myelomonocytic leukemia cells (U937)

Rosato, R. R., Wang, Z., Gopalkrishnan, R. V., Fisher, P. B., & Grant, S. (2001) · International Journal of Oncology · doi:10.3892/ijo.19.1.181 · Cited by 87 · see citing works

Alterations of MAPK Activities Associated with Intestinal Cell Differentiation

Ding, Q., Wang, Q., & Evers, B. M. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.4969 · Cited by 83 · see citing works

Transcriptional Response of a Human Colon Adenocarcinoma Cell Line to Sodium Butyrate

Iacomino, G., Tecce, M. F., Grimaldi, C., Tosto, M., & Russo, G. L. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5323 · Cited by 76 · see citing works

Colonic fermentation: metabolic and clinical implications

Soergel, K. H. (1994) · Journal of Molecular Medicine · doi:10.1007/bf00180540 · Cited by 60 · see citing works

Mass Isotopomer Study of Glutamine Oxidation and Synthesis in Primary Culture of Astrocytes

Lee, W. N. P., Edmond, J., Bassilian, S., & Morrow, J. W. (2007) · Developmental Neuroscience · doi:10.1159/000111442 · Cited by 48 · see citing works

Stable Isotopes and Mass Isotopomer Study of Fatty Acid and Cholesterol Synthesis

Lee, W. N. P. (1996) · Advances in experimental medicine and biology · doi:10.1007/978-1-4613-1151-5_8 · Cited by 39 · see citing works

Tumor cell differentiation by butyrate and environmental stress

Witt, O., Schulze, S., Kanbach, K., Roth, C. L., & Pekrun, A. (2001) · Cancer Letters · doi:10.1016/s0304-3835(01)00628-0 · Cited by 28 · see citing works

Short Chain Fatty Acids Differentially Modulate Cellular Phenotype and c-myc Protein Levels in Primary Human Nonmalignant and Malignant Colonocytes

Emenaker, N. J., & Basson, M. D. (2001) · Digestive Diseases and Sciences · doi:10.1023/a:1005661809250 · Cited by 20 · see citing works

Sodium butyrate modulates p53 and Bcl-2 expression in human retinoblastoma cell lines.

Madigan, M. C., Chaudhri, G., Penfold, P. L., & Conway, R. M. (1999) · PubMed · Cited by 19 · see citing works

Feasibility of analysing [13C]urea breath tests for Helicobacter pylori by gas chromatography‐mass spectrometry in the selected ion monitoring mode

Kasho, V. N., CHENG, S., JENSEN, D. M., Ajie, H. O., LEE, W. P., & Faller, L. D. (1996) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1996.99271000.x · Cited by 18 · see citing works

ATP citrate lyase inhibition can suppress tumor cell growth

Hatzivassiliou, G., Zhao, F., Bauer, D. E., Andreadis, C., Shaw, A. N., Dhanak, D., Hingorani, S. R., Tuveson, D. A., & Thompson, C. B. (2005) · Cancer Cell · doi:10.1016/j.ccr.2005.09.008 · Cited by 1,086 · see citing works

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

Massie, C. E., Lynch, A., Ramos‐Montoya, A., Boren, J., Stark, R., Fazli, L., Warren, A., Scott, H., Madhu, B., Sharma, N., et al. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.158 · Cited by 624 · see citing works

Changes in Transcript Abundance in <i>Chlamydomonas reinhardtii</i> following Nitrogen Deprivation Predict Diversion of Metabolism

Miller, R., Wu, G., Deshpande, R. R., Vieler, A., Gärtner, K., Li, X., Moellering, E. R., Zäuner, S., Cornish, A. J., Liu, B., et al. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.165159 · Cited by 511 · see citing works

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells

Zhang, J., Khvorostov, I., Hong, J. S., Oktay, Y., Vergnes, L., Nuebel, E., Wahjudi, P. N., Setoguchi, K., Wang, G., Do, A., et al. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.401 · Cited by 499 · see citing works

Gut microbiota role in irritable bowel syndrome: New therapeutic strategies

Distrutti, E., Monaldi, L., Ricci, P., & Fiorucci, S. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i7.2219 · Cited by 320 · see citing works

Gut Microbiota, Bacterial Translocation, and Interactions with Diet: Pathophysiological Links between Major Depressive Disorder and Non-Communicable Medical Comorbidities

Slyepchenko, A., Maes, M., Jacka, F. N., Köhler, C. A., Barichello, T., McIntyre, R. S., Berk, M., Grande, I., Foster, J. A., Vieta, E., et al. (2017) · Psychotherapy and Psychosomatics · doi:10.1159/000448957 · Cited by 278 · see citing works

Fluxome analysis using GC-MS.

Wittmann, C. (2007) · Microbial Cell Factories · doi:10.1186/1475-2859-6-6 · Cited by 225 · see citing works

Does butyrate protect from colorectal cancer?

Sengupta, S., Muir, J. G., & Gibson, P. R. (2006) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04213.x · Cited by 219 · see citing works

Butyrate and Colorectal Cancer: The Role of Butyrate Transport

Gonçalves, P., & Martel, F. (2013) · Current Drug Metabolism · doi:10.2174/1389200211314090006 · Cited by 179 · see citing works

The effects of butyrate enemas on visceral perception in healthy volunteers

Vanhoutvin, S. A. L. W., Troost, F. J., Kilkens, T. O. C., Lindsey, P. J., Hamer, H. M., Jonkers, D. M. A. E., Venema, K., & Brummer, R. ‐. M. (2009) · Neurogastroenterology &amp; Motility · doi:10.1111/j.1365-2982.2009.01324.x · Cited by 171 · see citing works

Metabolic strategy of boar spermatozoa revealed by a metabolomic characterization

Marín, S., Chiang, K., Bassilian, S., Lee, W. P., Boros, L. G., Fernández-Novell, J. M., Centelles, J. J., Medrano, A., Rodríguez-Gil, J. E., & Cascante, M. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)01185-2 · Cited by 164 · see citing works

Non-Digestible Food Ingredients, Colonic Microbiota and the Impact on Gut Health and Immunity: A Role for Metabolomics

Jacobs, D. M., Gaudier, E. A., van Duynhoven, J., & Vaughan, E. E. (2009) · Current Drug Metabolism · doi:10.2174/138920009787048383 · Cited by 162 · see citing works

Metabolic analysis of antibody producing CHO cells in fed‐batch production

Dean, J. T., & Reddy, P. (2013) · Biotechnology and Bioengineering · doi:10.1002/bit.24826 · Cited by 138 · see citing works

Faecal tumour M2 pyruvate kinase: a new, sensitive screening tool for colorectal cancer

Hardt, P. D., Mazurek, S., Toepler, M., Schlierbach, P., Bretzel, R. G., EIGENBRODT, E., & Kloer, H. U. (2004) · British Journal of Cancer · doi:10.1038/sj.bjc.6602033 · Cited by 134 · see citing works

Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex

Blouin, J., Penot, G., Collinet, M., Nacfer, M., Forest, C. D., Laurent‐Puig, P., Coumoul, X., Barouki, R., Benelli, C., & Bortoli, S. (2010) · International Journal of Cancer · doi:10.1002/ijc.25599 · Cited by 131 · see citing works

High-protein diet modifies colonic microbiota and luminal environment but not colonocyte metabolism in the rat model: The increased luminal bulk connection

Liu, X., Blouin, J.-M., Santacruz, A., Lan, A., Andriamihaja, M., Wilkanowicz, S., Benetti, P.-H., Tomé, D., Sanz, Y., Blachier, F., et al. (2014) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00400.2013 · Cited by 103 · see citing works

Metabolomics by Proton Nuclear Magnetic Resonance Spectroscopy of the Response to Chloroethylnitrosourea Reveals Drug Efficacy and Tumor Adaptive Metabolic Pathways

Morvan, D., & Demidem, A. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-2346 · Cited by 103 · see citing works

Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets

Vizán, P., Sánchez‐Tena, S., Alcarraz‐Vizán, G., Soler, M., Messeguer, R., Pujol, M. D., Lee, W.-N. P., & Cascante, M. (2009) · Carcinogenesis · doi:10.1093/carcin/bgp083 · Cited by 94 · see citing works

Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome

Benito, A., Polat, I. H., Noé, V., Ciudad, C. J., Marín, S., & Cascante, M. (2017) · Oncotarget · doi:10.18632/oncotarget.21601 · Cited by 83 · see citing works

Metabolomics in cell culture—A strategy to study crucial metabolic pathways in cancer development and the response to treatment

Halama, A. (2014) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2014.09.002 · Cited by 82 · see citing works

Short-Chain Fatty Acids Induce Apoptosis in Colon Cancer Cells Associated with Changes to Intracellular Redox State and Glucose Metabolism

Matthews, G. M., Howarth, G. S., & Butler, R. N. (2012) · Chemotherapy · doi:10.1159/000335672 · Cited by 82 · see citing works

Experimental colitis: decreased Octn2 and Atb0+ expression in rat colonocytes induces carnitine depletion that is reversible by carnitine‐loaded liposomes

D’Argenio, G., Calvani, M., Casamassimi, A., Petillo, O., Margarucci, S., Rienzo, M., Peluso, I., Calvani, R., Ciccodicola, A., Caporaso, N., et al. (2006) · The FASEB Journal · doi:10.1096/fj.06-5950fje · Cited by 81 · see citing works

Electrochemical Biosensing for Direct Biopsy Slices Screening for Colorectal Cancer Detection

Vernick, S., Freeman, A., Rishpon, J., Niv, Y., Vilkin, A., & Shacham‐Diamand, Y. (2010) · Journal of The Electrochemical Society · doi:10.1149/1.3507268 · Cited by 77 · see citing works

SIRT1 promotes GLUT1 expression and bladder cancer progression via regulation of glucose uptake

Chen, J., Cao, L., Li, Z., & Li, Y. (2019) · Human Cell · doi:10.1007/s13577-019-00237-5 · Cited by 76 · see citing works

Metabolomics, Pathway Regulation, and Pathway Discovery

Zhang, G., Sadhukhan, S., Tochtrop, G. P., & Brunengraber, H. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.r110.171405 · Cited by 70 · see citing works

Butyrate metabolism in human colon carcinoma cells: Implications concerning its growth‐inhibitory effect

Andriamihaja, M., Chaumontet, C., Tomé, D., & Blachier, F. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21556 · Cited by 69 · see citing works

Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer

Zecchini, V. R., Madhu, B., Russell, R., Pértega‐Gomes, N., Warren, A. Y., Gaude, E., Borlido, J., Stark, R., Zecchini, H. I., Rao, R. B., et al. (2014) · The EMBO Journal · doi:10.15252/embj.201386874 · Cited by 63 · see citing works

Energy Metabolism in H460 Lung Cancer Cells: Effects of Histone Deacetylase Inhibitors

Amoêdo, N. D., Rodrigues, M. F., Pezzuto, P., Galina, A., da Costa, R. M., Almeida, F. C. L., El‐Bacha, T., & Rumjanek, F. D. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022264 · Cited by 61 · see citing works

Phosphoglycerate Mutase-derived Polypeptide Inhibits Glycolytic Flux and Induces Cell Growth Arrest in Tumor Cell Lines

Engel, M., Mazurek, S., EIGENBRODT, E., & Welter, C. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402768200 · Cited by 61 · see citing works

Gaining Insight into Microbial Physiology in the Large Intestine: A Special Role for Stable Isotopes

de Graaf, A. A., & Venema, K. (2007) · Advances in microbial physiology/Advances in Microbial Physiology · doi:10.1016/s0065-2911(07)53002-x · Cited by 60 · see citing works

Short-chain fatty acid modulation of apoptosis in the kato III human gastric carcinoma cell line

Matthews, G. M., Howarth, G. S., & Butler, R. N. (2007) · Cancer Biology & Therapy · doi:10.4161/cbt.6.7.4318 · Cited by 60 · see citing works

The Warburg effect: a balance of flux analysis

Vaitheesvaran, B., Xu, J., Yee, J. K., Lu, Q., Go, V. L. W., Xiao, G. G., & Lee, W. N. (2014) · Metabolomics · doi:10.1007/s11306-014-0760-9 · Cited by 58 · see citing works

The role of glucose metabolism and glucose-associated signalling in cancer.

Wittig, R., & Coy, J. F. (2008) · PubMed Central · Cited by 56 · see citing works

De novo lipogenesis represents a therapeutic target in mutant Kras non‐small cell lung cancer

Singh, A., Ruiz, C. F., Bhalla, K., Haley, J. D., Li, Q. K., Acquaah-Mensah, G. K., Montal, E. D., Sudini, K. R., Skoulidis, F., Wistuba, I. I., et al. (2018) · The FASEB Journal · doi:10.1096/fj.201800204 · Cited by 55 · see citing works

Carbon nanotubes based electrochemical biosensor for detection of formaldehyde released from a cancer cell line treated with formaldehyde-releasing anticancer prodrugs

Bareket, L., Rephaeli, A., Berkovitch-Luria, G., Nudelman, A., & Rishpon, J. (2009) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2009.06.016 · Cited by 53 · see citing works

The Impact of Carnitine on Dietary Fiber and Gut Bacteria Metabolism and Their Mutual Interaction in Monogastrics

Ghonimy, A., Zhang, D., Farouk, M. H., & Wang, Q. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19041008 · Cited by 53 · see citing works

The Role of Intracellularly Released Formaldehyde and Butyric Acid in the Anticancer Activity of Acyloxyalkyl Esters

Nudelman, A., Levovich, I., Cutts, S. M., Phillips, D. R., & Rephaeli, A. (2005) · Journal of Medicinal Chemistry · doi:10.1021/jm049428p · Cited by 52 · see citing works

Quantitative two‐dimensional HRMAS 1H‐NMR spectroscopy‐based metabolite profiling of human cancer cell lines and response to chemotherapy

Bayet‐Robert, M., Loiseau, D., Rio, P. G., Demidem, A., Barthomeuf, C., Stepien, G., & Morvan, D. (2010) · Magnetic Resonance in Medicine · doi:10.1002/mrm.22303 · Cited by 52 · see citing works

Colonic butyrate- algesic or analgesic?: Colonic butyrate function

Kannampalli, P., Shaker, R., & Sengupta, J. N. (2011) · Neurogastroenterology &amp; Motility · doi:10.1111/j.1365-2982.2011.01775.x · Cited by 50 · see citing works

Role of eIF3a (eIF3 p170) in intestinal cell differentiation and its association with early development

Liu, Z., Dong, Z., Yang, Z., Chen, Q., Pan, Y., Yang, Y., Cui, P., Zhang, X., & Zhang, J. (2007) · Differentiation · doi:10.1111/j.1432-0436.2007.00165.x · Cited by 50 · see citing works

Colorectal Carcinogenesis: A Cellular Response to Sustained Risk Environment

Fung, K. Y. C., Ooi, C. C., Zucker, M., Lockett, T. J., Williams, D. B., Cosgrove, L. J., & Topping, D. L. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140713525 · Cited by 46 · see citing works

Electrochemical lab on a chip for high-throughput analysis of anticancer drugs efficiency

Popovtzer, R., Neufeld, T., Popovtzer, A., Rivkin, I., Margalit, R., Engel, D., Nudelman, A., Rephaeli, A., Rishpon, J., & Shacham‐Diamand, Y. (2008) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2008.03.002 · Cited by 44 · see citing works

Profiling of central metabolism in human cancer cells by two-dimensional NMR, GC-MS analysis, and isotopomer modeling

Chen, Y., Richardson, A. D., Osterman, A. L., & Smith, J. W. (2007) · Metabolomics · doi:10.1007/s11306-007-0094-y · Cited by 41 · see citing works

Hydrolysed inulin alleviates the azoxymethane-induced preneoplastic aberrant crypt foci by altering selected intestinal microbiota in Sprague–Dawley rats

Pattananandecha, T., Sirilun, S., Duangjitcharoen, Y., Sivamaruthi, B. S., Suwannalert, P., Peerajan, S., & Chaiyasut, C. (2016) · Pharmaceutical Biology · doi:10.3109/13880209.2015.1110597 · Cited by 41 · see citing works

The Role of Glucose Metabolism and Glucose-Associated Signalling in Cancer

Wittig, R., & Coy, J. F. (2007) · Perspectives in Medicinal Chemistry · doi:10.1177/1177391x0700100006 · Cited by 57 · see citing works

Hypoxanthine–xanthine oxidase down-regulates GLUT1 transcription via SIRT1 resulting in decreased glucose uptake in human placenta

Lappas, M., Andrikopoulos, S., & Permezel, M. (2012) · Journal of Endocrinology · doi:10.1530/joe-11-0355 · Cited by 39 · see citing works

Epicatechin Gallate Impairs Colon Cancer Cell Metabolic Productivity

Sánchez‐Tena, S., Alcarraz‐Vizán, G., Marín, S., Torres, J. L., & Cascante, M. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf3052785 · Cited by 38 · see citing works

Histone deacetylase inhibition results in a common metabolic profile associated with HT29 differentiation

Alcarraz‐Vizán, G., Boren, J., Lee, W. P., & Cascante, M. (2010) · Metabolomics · doi:10.1007/s11306-009-0192-0 · Cited by 36 · see citing works

Nutrient-Gene Interaction: Tracer-Based Metabolomics-

Lee, W. P., & Go, V. L. W. (2005) · Journal of Nutrition · doi:10.1093/jn/135.12.3027s · Cited by 36 · see citing works

Chronic acetyl-L-carnitine treatment alleviates behavioral deficits and neuroinflammation through enhancing microbiota derived-SCFA in valproate model of autism

Zahedi, E., Sadr, S. S., Sanaeierad, A., & Roghani, M. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114848 · Cited by 34 · see citing works

Mitochondrial bioenergetic background confers a survival advantage to HepG2 cells in response to chemotherapy

Loiseau, D., Morvan, D., Chevrollier, A., Demidem, A., Douay, O., Reynier, P., & Stepien, G. (2009) · Molecular Carcinogenesis · doi:10.1002/mc.20539 · Cited by 28 · see citing works

Bioactive Food Components and Cancer‐Specific Metabonomic Profiles

Kim, Y. S., & Milner, J. A. (2010) · BioMed Research International · doi:10.1155/2011/721213 · Cited by 26 · see citing works

Nutrient and antioxidant modulation of apoptosis in gastric and colon cancer cells

Matthews, G. M., Howarth, G. S., & Butler, R. N. (2006) · Cancer Biology & Therapy · doi:10.4161/cbt.5.6.2868 · Cited by 25 · see citing works

Characterizing phenotype with tracer based metabolomics

Lee, W.-N. P. (2006) · Metabolomics · doi:10.1007/s11306-006-0017-3 · Cited by 23 · see citing works

Faecal M2-pyruvate kinase: a novel, noninvasive marker of ileal pouch inflammation

Johnson, M. W., Maestranzi, S., Duffy, A. M., Dewar, D. H., Ciclitira, P. J., Sherwood, R. A., & Nicholls, J. R. (2009) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0b013e3283040cb3 · Cited by 20 · see citing works

Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1

Sánchez‐Tena, S., Vizán, P., Dudeja, P. K., Centelles, J. J., & Cascante, M. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.08.009 · Cited by 19 · see citing works

Blastomere removal from cleavage-stage mouse embryos alters placental function, which is associated with placental oxidative stress and inflammation

Yao, Q. Z., Chen, L., Liang, Y., Sui, L., Guo, L., Zhou, J., Fan, K., Jing, J., Zhang, Y., & Yao, B. (2016) · Scientific Reports · doi:10.1038/srep25023 · Cited by 19 · see citing works

Butyrate Alters Pyruvate Flux and Induces Lipid Accumulation in Cultured Colonocytes

Bekebrede, A. F., van Deuren, T., Gerrits, W. J. J., Keijer, J., & de Boer, V. C. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222010937 · Cited by 18 · see citing works

Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: Trichostatin A as a case study

Alcarraz‐Vizán, G., Sánchez‐Tena, S., Moyer, M. P., & Cascante, M. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.12.024 · Cited by 16 · see citing works

SiDMAP: a metabolomics approach to assess the effects of drug candidates on the dynamic properties of biochemical pathways

Maguire, G., Lee, P., Manheim, D., & Boros, L. G. (2006) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.1.4.351 · Cited by 15 · see citing works

Homeodomain transcription factor CDX1 is required for the transcriptional induction of PPARγ in intestinal cell differentiation

Park, M. J., Kim, H. Y., Kim, K., & Cheong, J. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.11.030 · Cited by 12 · see citing works

The Production of Listeriolysin O and Subsequent Intracellular Infections by Listeria monocytogenes Are Regulated by Exogenous Short Chain Fatty Acid Mixtures

Rinehart, E., Chapman, J. I., & Sun, Y. (2020) · Toxins · doi:10.3390/toxins12040218 · Cited by 9 · see citing works

Unveiling the Metabolic Changes on Muscle Cell Metabolism Underlying p-Phenylenediamine Toxicity

de Mas, I. M., Marín, S., Pachón, G., Rodríguez‐Prados, J., Vizán, P., Centelles, J. J., Tauler, R., Azqueta, A., Selivanov, V. A., de Ceráin, A. L., et al. (2017) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2017.00008 · Cited by 9 · see citing works

Development of Tracer-Based Metabolomics and its Implications for the Pharmaceutical Industry

Maguire, G., Boros, L. G., & Lee, P. (2007) · International Journal of Pharmaceutical Medicine · doi:10.2165/00124363-200721030-00004 · Cited by 6 · see citing works

Cancer cell sensitization and improved treatment efficacy by combined sodium butyrate and paclitaxel formulations is cancer-type specific

Rivkin, I., Cohen, K., Bod, T., Argov, M., & Margalit, R. (2013) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.12.021 · Cited by 6 · see citing works

Metabolomics in Systems Toxicology: Towards Personalized Medicine

Schnackenberg, L. K., Sun, J., & Beger, R. D. (2009) · General, Applied and Systems Toxicology · doi:10.1002/9780470744307.gat217 · Cited by 5 · see citing works

Protein Acetylation as an Integral Part of Metabolism in Cancer Development and Progression

Čuperlović‐Culf, M., & Culf, A. S. (2014) · Cited by 4 · see citing works

The effects of gut microbiota-derived short-chain fatty acids (SCFAs) on human colon cancer cells: An in vitro study

Darabi, S., Keshavarzi, F., Ashtari, P., Motamedi-Sedeh, F., & Alirezapour, B. (2025) · Journal of Genetic Engineering and Biotechnology · doi:10.1016/j.jgeb.2025.100610 · Cited by 3 · see citing works

Fluxomics

Cascante, M., Benito, A., de Mas, I. M., Centelles, J. J., Miranda, A., & de Atauri, P. (2013) · Springer eBooks · doi:10.1007/978-3-319-01008-3_12 · Cited by 3 · see citing works

Modeling Networks of Glycolysis, Overall Energy Metabolism and Drug Metabolism under a Systems Biology Approach

Sarnyai, Z., & Boros, L. G. (2008) · Annual reports in medicinal chemistry · doi:10.1016/s0065-7743(08)00020-1 · Cited by 2 · see citing works

Application of Tracer-Based Metabolomics and Flux Analysis in Targeted Cancer Drug Design

Cascante, M., Selivanov, V. A., & Ramos‐Montoya, A. (2012) · Methods in pharmacology and toxicology · doi:10.1007/978-1-61779-618-0_10 · Cited by 2 · see citing works

Nano-Bio Electrochemical Interfacing–Linking Cell Biology and Micro-Electronics

Shacham‐Diamand, Y., Popovtzer, R., & Rishpon, Y. (2009) · Nanostructure science and technology · doi:10.1007/978-1-4419-1424-8_12 · Cited by 1 · see citing works

8.2 Modeling of Regulation of Glycolysis and Overall Energy Metabolism Under a Systems Biology Approach

Cascante, M., Boros, L. G., & Boren, J. (2007) · Springer eBooks · doi:10.1007/978-0-387-30411-3_31 · Cited by 1 · see citing works

Metabolism of the challenged intestinal epithelial cell

Bekebrede, A. F. (2023) · doi:10.18174/578215 · Cited by 1 · see citing works

Caracterització de l'efecte de compostos naturals en models in vitro i in vivo de càncer de còlon

Tena, S. S. (2012) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Caracterització metabòlica de la transformació i la progressió tumoral i anàlisi de l'efecte de nous compostos amb potencial terapèutic

Porquet, M. Z. (2010) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

The colorectal response to butyrate in health and IBS

Vanhoutvin, S. A. L. W. (2014) · doi:10.26481/dis.20141106sv

The study of RAS-induced metabolic reprogramming and the role of the pentose phosphate pathway in tumor metabolism

Mauricio, A. B. (2014) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Histone deacetylase inhibition results in a common metabolic profile associated with HT29 differentiation

Alcarraz‐Vizán, G., Boren, J., Lee, W. P., & Cascante, M. (2010) · Metabolomics · doi:10.1007/s11306-009-0192-0 · Cited by 36 · see citing works

Energy state in HT-29 cells is linked to differentiation

Graz, C. J. M., & Cowley, H. M. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0047-9 · Cited by 5 · see citing works

Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex

Blouin, J., Penot, G., Collinet, M., Nacfer, M., Forest, C. D., Laurent‐Puig, P., Coumoul, X., Barouki, R., Benelli, C., & Bortoli, S. (2010) · International Journal of Cancer · doi:10.1002/ijc.25599 · Cited by 131 · see citing works

Enterocytic differentiation of a subpopulation of the human colon tumor cell line HT‐29 selected for growth in sugar‐free medium and its inhibition by glucose

Zweibaum, A., Pinto, M., Chevalier, G., Dussaulx, E., Triadou, N., Lacroix, B. D., HAFFEN, K., Brun, J.-F., & Rousset, M. (1985) · Journal of Cellular Physiology · doi:10.1002/jcp.1041220105 · Cited by 341 · see citing works

Butyrate rapidly induces growth inhibition and differentiation

Barnard, J. A., & Warwick, G. J. (1993)