SIRT1 Functionally Interacts with the Metabolic Regulator and Transcriptional Coactivator PGC-1α

Oxidants, oxidative stress and the biology of ageing

Finkel, T., & Holbrook, N. J. (2000) · Nature · doi:10.1038/35041687 · Cited by 9,413

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80611-x · Cited by 4,139

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Imai, S.-I., Armstrong, C. M., Kaeberlein, M., & Guarente, L. (2000) · Nature · doi:10.1038/35001622 · Cited by 3,510

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., Tran, H., Ross, S. E., Mostoslavsky, R., Cohen, H. Y., et al. (2004) · Science · doi:10.1126/science.1094637 · Cited by 3,239

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Yeung, F., Hoberg, J. E., Ramsey, C. S., Keller, M. D., Jones, D. R., Frye, R. A., & Mayo, M. W. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600244 · Cited by 2,750

hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

Vaziri, H., Dessain, S. K., Eaton, E. N., Imai, S., Frye, R. A., Pandita, T. K., Guarente, L., & Weinberg, R. A. (2001) · Cell · doi:10.1016/s0092-8674(01)00527-x · Cited by 2,690

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

Kaeberlein, M., McVey, M., & Guarente, L. (1999) · Genes & Development · doi:10.1101/gad.13.19.2570 · Cited by 2,253

Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

Luo, J., Nikolaev, A. Y., Imai, S.-I., Chen, D., Su, F., Shiloh, A., Guarente, L., & Gu, W. (2001) · Cell · doi:10.1016/s0092-8674(01)00524-4 · Cited by 2,081

Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator

Puigserver, P., & Spiegelman, B. M. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0012 · Cited by 2,076

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

Cohen, H. Y., Miller, C., Bitterman, K. J., Wall, N. R., Hekking, B., Kessler, B., Howitz, K. T., Gorospe, M., de Cabo, R., & Sinclair, D. A. (2004) · Science · doi:10.1126/science.1099196 · Cited by 1,924

Innovative Cosmeceuticals: Sirtuin Activators and Anti-Glycation Compounds

Farris, P. K. (2011) · Seminars in Cutaneous Medicine and Surgery · doi:10.1016/j.sder.2011.05.004 · Cited by 22

Hypercholesterolemia and neurodegeneration. Comparison of hippocampal phenotypes in LDLr knockout and APPswe/PS1dE9 mice

Ettcheto, M., Petrov, D., Pedrós, I., de Lemos, L., Pallàs, M., Alegret, M., Laguna, J. C., Folch, J., & Camins, A. (2015) · Experimental Gerontology · doi:10.1016/j.exger.2015.03.010 · Cited by 22

γ-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction

Wang, A., Li, D., Wang, S., Zhou, F., Li, P., Wang, Y., & Lin, L. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.11.047 · Cited by 22

Cardiovascular Adaptive Homeostasis in Exercise

Davies, K. J. A. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00369 · Cited by 24

Alternate day fasting impacts the brain insulin‐signaling pathway of young adult male C57BL/6 mice

Lu, J., Lezi, E., Wang, W., Frontera, J. R., Zhu, H., Wang, W., Lee, P., Choi, I. Y., Brooks, W. M., Burns, J. M., et al. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07184.x · Cited by 23

Sciadopitysin alleviates methylglyoxal-mediated glycation in osteoblastic MC3T3-E1 cells by enhancing glyoxalase system and mitochondrial biogenesis

Choi, E. M., Suh, K. S., Rhee, S. Y., & Kim, Y. S. (2014) · Free Radical Research · doi:10.3109/10715762.2014.903562 · Cited by 21

Pathobiochemistry of Aging and Neurodegeneration: Deregulation of NAD+ Metabolism in Brain Cells

Kolotyeva, N. A., Groshkov, A. A., Rozanova, N. A., Berdnikov, A. K., Novikova, S. V., Komleva, Y. K., Salmina, A. B., Illarioshkin, S. N., & Пирадов, М. А. (2024) · Biomolecules · doi:10.3390/biom14121556 · Cited by 24

Molecular mechanisms and potential interventions during aging-associated sarcopenia

Luo, X., Wang, J., Ju, Q., Li, T., & Bi, X. (2024) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2024.112020 · Cited by 23

Temporal overexpression of SIRT1 in skeletal muscle of adult mice does not improve insulin sensitivity or markers of mitochondrial biogenesis

Svensson, K., LaBarge, S. A., Martins, V. F., & Schenk, S. (2017) · Acta Physiologica · doi:10.1111/apha.12897 · Cited by 22

Identification of Compounds That Inhibit Estrogen-Related Receptor Alpha Signaling Using High-Throughput Screening Assays

Lynch, C., Zhao, J., Sakamuru, S., Zhang, L., Huang, R., Witt, K. L., Merrick, B. A., Teng, C. T., & Xia, M. (2019) · Molecules · doi:10.3390/molecules24050841 · Cited by 21

Silent information regulator 1 ameliorates oxidative stress injury via PGC-1α/PPARγ-Nrf2 pathway after ischemic stroke in rat

Zhou, Y., Li, P., Li, Y., & Zhao, Y. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.11.001 · Cited by 21

Repurposing ezetimibe as a neuroprotective agent in a rotenone-induced Parkinson’s disease model in rats: Role of AMPK/SIRT-1/PGC-1α signaling and autophagy

Elesawy, W. H., El-Sahar, A. E., Sayed, R. H., Ashour, A. M., Alsufyani, S. E., Arab, H. H., & Kandil, E. A. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112640 · Cited by 22

Does SIRT1 determine exercise-induced skeletal muscle mitochondrial biogenesis: differences between in vitro and in vivo experiments?

Gurd, B. J., Little, J. P., & Perry, C. G. R. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01262.2011 · Cited by 22

Sirt1 activator induces proangiogenic genes in preadipocytes to rescue insulin resistance in diet-induced obese mice

Nawaz, A., Mehmood, A., Kanatani, Y., Kado, T., Igarashi, Y., Takikawa, A., Yamamoto, S., Okabe, K., Nakagawa, T., Yagi, K., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-29773-0 · Cited by 20

Suppression of myopathic lamin mutations by muscle-specific activation ofAMPKand modulation of downstream signaling

Chandran, S., Suggs, J. A., Wang, B. J., Han, A., Bhide, S., Cryderman, D. E., Moore, S. A., Bernstein, S. I., Wallrath, L. L., & Melkani, G. C. (2018) · Human Molecular Genetics · doi:10.1093/hmg/ddy332 · Cited by 20

Sirtuins: A Family of Proteins With Implications for Human Performance and Exercise Physiology

Lappalainen, Z. (2010) · Research in Sports Medicine · doi:10.1080/15438627.2011.536068 · Cited by 20

Improvement of oocyte quality through the SIRT signaling pathway

Vo, K., Sato, Y., & Kawamura, K. (2023) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12510 · Cited by 21

Oxymatrine and insulin resistance: Focusing on mechanistic intricacies involve in diabetes associated cardiomyopathy via SIRT1/AMPK and TGF‐β signaling pathway

Seksaria, S., Mehan, S., Dutta, B. J., Gupta, G. D., Ganti, S. S., & Singh, A. (2023) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.23330 · Cited by 23

Transcription factor EB: A potential integrated network regulator in metabolic-associated cardiac injury

Wen, W., Zheng, H., Li, W., Huang, G., Chen, P., Zhu, X., Cao, Y., Li, J., Huang, X., & Huang, Y. (2023) · Metabolism · doi:10.1016/j.metabol.2023.155662 · Cited by 20

Scrapie Infection in Experimental Rodents and SMB-S15 Cells Decreased the Brain Endogenous Levels and Activities of Sirt1

Wang, J., Zhang, J., Shi, Q., Zhang, B., Chen, C., Chen, L., Sun, J. F., Wang, H., Xiao, K., & Dong, X. (2014) · Journal of Molecular Neuroscience · doi:10.1007/s12031-014-0459-4 · Cited by 20

Mitochondrial Dysfunction and Oxidative and Endoplasmic Reticulum Stress in Argyrophilic Grain Disease

Ilieva, E. V., Kichev, A., Naudí, A., Ferrer, I., Pamplona, R., & Portero‐Otín, M. (2011) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31820f8765 · Cited by 20

AMP-activated protein kinase controls metabolism and heat production during embryonic development in birds

Walter, I. J., Hegarty, B. D., & Seebacher, F. (2010) · Journal of Experimental Biology · doi:10.1242/jeb.043349 · Cited by 21

Response of BAX, Bcl-2 Proteins, and SIRT1/PGC-1α mRNA Expression to 8-Week Treadmill Running in the Aging Rat Skeletal Muscle

Li, F., Yu, H., Lin, X., & Liu, Y. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-38810-6_38 · Cited by 20

Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri

Kabiljo, J., Murko, C., Pusch, O., & Zupkovitz, G. (2019) · Gene Expression Patterns · doi:10.1016/j.gep.2019.05.001 · Cited by 20

Dietary whey protein stimulates mitochondrial activity and decreases oxidative stress in mouse female brain

Shertzer, H. G., Krishan, M., & Genter, M. B. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.05.061 · Cited by 20

Less is more: Caloric regulation of neurogenesis and adult brain function

Morgan, A. H., Andrews, Z. B., & Davies, J. S. (2017) · Journal of Neuroendocrinology · doi:10.1111/jne.12512 · Cited by 22

Mitochondrial Genome-Encoded Long Noncoding RNA Cytochrome B and Mitochondrial Dysfunction in Diabetic Retinopathy

Mohammad, G., Kumar, J., & Kowluru, R. A. (2023) · Antioxidants and Redox Signaling · doi:10.1089/ars.2023.0303 · Cited by 20

Mitochondrial dynamics in the mouse liver infected by Schistosoma mansoni

Chen, T. T.-W., Wu, L. S.-H., Hsu, P. W.-C., Pang, C., Lee, K.-M., Cheng, P.-C., & Peng, S.-Y. (2015) · Acta Tropica · doi:10.1016/j.actatropica.2015.04.004 · Cited by 19

Bouchardatine suppresses rectal cancer in mice by disrupting its metabolic pathways via activating the SIRT1-PGC-1α-UCP2 axis

Xu, Y., Song, Q., Li, C., Hu, Y., Song, B., Ye, J., Rao, Y., & Huang, Z. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.04.029 · Cited by 20

Systematic identification of Class I HDAC substrates

Li, T., Song, B., Wu, Z., Lu, M., & Zhu, W. (2013) · Briefings in Bioinformatics · doi:10.1093/bib/bbt060 · Cited by 19

Integrin-Dependent Akt1 Activation Regulates PGC-1 Expression and Fatty Acid Oxidation

Beeson, C., Beeson, G. C., Buff, H., Eldridge, J. D., Zhang, A., Seth, A. K., Demcheva, M. V., Vournakis, J. N., & Muise‐Helmericks, R. C. (2012) · Journal of Vascular Research · doi:10.1159/000332326 · Cited by 19

The Heat Shock Connection of Metabolic Stress and Dietary Restriction

Dancsó, B., Spiró, Z., Arslan, M. A., Nguyen, M., Papp, D., Csermely, P., & Sőti, C. (2010) · Current Pharmaceutical Biotechnology · doi:10.2174/138920110790909704 · Cited by 20

The Role of Sirtuins in Sarcopenia and Frailty

Anwar, M., Pradhan, R., Dey, S., & Kumar, R. (2023) · Aging and disease · doi:10.14336/ad.2022.0622 · Cited by 19

Neurobiological Opportunities in Diabetic Polyneuropathy

Poitras, T. M., Munchrath, E., & Zochodne, D. W. (2021) · Neurotherapeutics · doi:10.1007/s13311-021-01138-y · Cited by 20

Sirtuins play critical and diverse roles in acute kidney injury

Peasley, K., Chiba, T., Goetzman, E. S., & Sims‐Lucas, S. (2021) · Pediatric Nephrology · doi:10.1007/s00467-020-04866-z · Cited by 18

Glomerular mitochondrial changes in HIV associated renal injury

Bryant, J., Guda, P. R., Asemu, G., Subedi, R., Ray, S., Khalid, O. S., Shukla, V., Patel, D., Davis, H., Nimmagadda, V. K. C., et al. (2018) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2018.03.004 · Cited by 17

Sirtuin deficiency and the adverse effects of fructose and uric acid synthesis

Rodríguez‐Iturbe, B., Johnson, R. J., Lanaspa, M. A., Nakagawa, T., García‐Arroyo, F. E., & Sánchez‐Lozada, L. G. (2022) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00238.2021 · Cited by 17

24-Hydroxycholesterol Induces Tau Proteasome-Dependent Degradation via the SIRT1/PGC1α/Nrf2 Pathway: A Potential Mechanism to Counteract Alzheimer’s Disease

Testa, G., Giannelli, S., Sottero, B., Staurenghi, E., Giaccone, G., Caroppo, P., Gamba, P., & Leonarduzzi, G. (2023) · Antioxidants · doi:10.3390/antiox12030631 · Cited by 20

Protection against myocardial ischemia/reperfusion injury in mice by 3-caffeoylquinic acid isomers isolated from Saxifraga tangutica

Tong, Y., Li, G., Shi, X.-B., Wang, L., Zhou, J., Chu, M., Wang, Z., El‐Aty, A. M. A., & Dang, J. (2024) · RSC Advances · doi:10.1039/d4ra00046c · Cited by 17

Nobiletin enhances mitochondrial function by regulating SIRT1/PGC-1α signaling in porcine oocytes during in vitro maturation

Lee, S., Li, X., Lu, Q., Zhan, C., Kim, J.-D., Lee, G.-H., Sim, J.-M., & Cui, X. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.149747 · Cited by 17

The hyaluronic acid inhibitor 4-methylumbelliferone is an NSMase2 activator—role of Ceramide in MU anti-tumor activity

Qin, J., Kilkus, J. P., & Dawson, G. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2015.11.001 · Cited by 17

Physical Activity, Dietary Calorie Restriction, and Cancer

McTiernan, A. (2010) · Springer eBooks · doi:10.1007/978-1-4419-7551-5 · Cited by 17

Nutritional biomarkers: Current view and future perspectives

Pande, S., Kratasyuk, V. A., Медведева, Н. Н., Kolenchukova, O. A., & Salmina, A. B. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1350136 · Cited by 18

Doxorubicin persistently rewires cardiac circadian homeostasis in mice

Ferreira, L. L., Cervantes, M., Froufe, H. J. C., Egas, C., Cunha‐Oliveira, T., Sassone‐Corsi, P., & Oliveira, P. J. (2019) · Archives of Toxicology · doi:10.1007/s00204-019-02626-z · Cited by 17

Improved mass spectrometry-based activity assay reveals oxidative and metabolic stress as sirtuin-1 regulators

Shao, D., Yao, C., Kim, M. H., Fry, J., Cohen, R. A., Costello, C. E., Matsui, R., Seta, F., McComb, M. E., & Bachschmid, M. M. (2019) · Redox Biology · doi:10.1016/j.redox.2019.101150 · Cited by 16

Cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tissue to support fuel preference for fatty acids

Park, C., Park, M., Kelly, M. E., Cheng, H., Lee, S. R., Jang, C., & Chang, J. S. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115888 · Cited by 16

Modulation of Nrf2 and Mitochondrial Function: Pharmacological Implications

Saso, L., Ateş, İ., Tunc, R., Yılmaz, B., Gallorini, M., Carradori, S., & Süzen, S. (2025) · Pharmaceuticals · doi:10.3390/ph18111698 · Cited by 18

Up-regulation of Sirtuin-1/autophagy signaling in human cerebral ischemia: possible role in caspase-3 mediated apoptosis

Teertam, S. K., & Babu, P. P. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e12278 · Cited by 16

NAD + precursor nutritional supplements sensitize the brain to future ischemic events

Qu, W., Ralto, K. M., Qin, T., Cheng, Y., Zong, W., Luo, X., Pérez‐Pinzón, M. A., Parikh, S. M., & Ayata, C. (2023) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x231156500 · Cited by 17

A crosstalk between epigenetic modulations and non-alcoholic fatty liver disease progression

Ramezani, M., Zobeiry, M., Abdolahi, S., Hatami, B., Zali, M. R., & Baghaei, K. (2023) · Pathology - Research and Practice · doi:10.1016/j.prp.2023.154809 · Cited by 16

Danqi Tablet (丹七片) Regulates Energy Metabolism in Ischemic Heart Rat Model through AMPK/SIRT1-PGC-1α Pathway

Meng, H., Wang, Q., Li, N., He, H., Wen-ji, L., Wang, Q.-X., Sun, X., Jiao, S., Wang, Y., & Tu, P. (2019) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-019-3040-8 · Cited by 16

Hepatic PPARα Is Destabilized by SIRT1 Deacetylase in Undernourished Male Mice

Suh, J. H., Kim, K. H., Conner, M. E., Moore, D. D., & Preidis, G. A. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.831879 · Cited by 16

Hepatitis C virus core protein induces hepatic steatosis via Sirt1‐dependent pathway

Zhang, C., Wang, J., Zhang, H., Liu, S., Lee, H. J., Jin, W., & Cheng, J. (2017) · Liver International · doi:10.1111/liv.13581 · Cited by 16

Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation

Dent, J. R., Martins, V. F., Svensson, K., LaBarge, S. A., Schlenk, N. C., Esparza, M. C., Buckner, E. H., Meyer, G. A., Hamilton, D. L., Schenk, S., et al. (2017) · Molecular Metabolism · doi:10.1016/j.molmet.2017.10.004 · Cited by 16

CSAG2 is a cancer‐specific activator of SIRT1

Yang, X., & Potts, P. R. (2020) · EMBO Reports · doi:10.15252/embr.202050912 · Cited by 16

Mitoquinone intravitreal injection ameliorates retinal ischemia–reperfusion injury in rats involving SIRT1 /Notch1/ NADPH axis

Tang, D., Liu, X., & Chen, J. (2022) · Drug Development Research · doi:10.1002/ddr.21911 · Cited by 15

NAD+ Therapeutics and Skeletal Muscle Adaptation to Exercise in Humans

Campelj, D. G., & Philp, A. (2022) · Sports Medicine · doi:10.1007/s40279-022-01772-2 · Cited by 20

Adropin: a key player in immune cell homeostasis and regulation of inflammation in several diseases

Wang, J., Ding, N., Chen, C., Gu, S., Liu, J., Wang, Y., Lin, L., Zheng, Y., & Li, Y. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1482308 · Cited by 15

Low‐ω3 Fatty Acid and Soy Protein Attenuate Alcohol‐Induced Fatty Liver and Injury by Regulating the Opposing Lipid Oxidation and Lipogenic Signaling Pathways

Reyes‐Gordillo, K., Shah, R., Varatharajalu, R., Garige, M., Leckey, L. C., & Lakshman, M. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/1840513 · Cited by 15

d -Allulose Ameliorates Hyperglycemia Through IRE1α Sulfonation-RIDD- Sirt1 Decay Axis in the Skeletal Muscle

Lee, H., Lee, G., Hoang, T., Park, S., Lee, J., Lim, J., Sa, S., Kim, G. E., Han, J. S., Kim, J., et al. (2022) · Antioxidants and Redox Signaling · doi:10.1089/ars.2021.0207 · Cited by 15

Involvement of the SIRT1/PGC-1α Signaling Pathway in Noise-Induced Hidden Hearing Loss

Liu, Y.-H., Jiang, Y., Li, C., Chen, X.-M., Huang, L.-G., Zhang, M., Ruan, B., & Wang, X. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.798395 · Cited by 15

PGC‐1α‐Induced Mitochondrial Alterations in 3T3 Fibroblast Cells

Liang, H., Bai, Y., Li, Y.-F., Richardson, A., & Ward, W. F. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1395.028 · Cited by 16

Caloric Restriction-Mediated Induction of Lipid Metabolism Gene Expression in Liver is Enhanced by Keap1-Knockdown

Kulkarni, S. R., Armstrong, L. E., & Slitt, A. L. (2013) · Pharmaceutical Research · doi:10.1007/s11095-013-1138-9 · Cited by 17

Dynamic Partnership between TFIIH, PGC-1α and SIRT1 Is Impaired in Trichothiodystrophy

Traboulsi, H., Davoli, S., Catez, P., Egly, J., & Compe, E. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004732 · Cited by 17

Proof of interaction between Leishmania SIR2RP1 deacetylase and chaperone HSP83

Monte-Alegre, A. F., Vergnes, B., Poncet, J., Mathieu-Daudé, F., Cordeiro‐da‐Silva, A., Ouaissi, A., & Séréno, D. (2006) · Parasitology Research · doi:10.1007/s00436-006-0352-3 · Cited by 15

Deterioration of mitochondrial biogenesis and degradation in the endometrium is a cause of subfertility in cows

Matsuyama, S., Nakamura, S., Minabe, S., Sakatani, M., Takenouchi, N., Sasaki, T., Inoue, Y., Iwata, H., & Kimura, K. (2023) · Molecular Reproduction and Development · doi:10.1002/mrd.23670 · Cited by 15

Free radical scavenging polyphenols isolated from Phyllanthus niruri L. ameliorates hyperglycemia via SIRT1 induction and GLUT4 translocation in in vitro and in vivo models

Swargiary, D., Kashyap, B., Sarma, P., Ahmed, S. A., Gurumayum, S., Barge, S., Basumatary, D., & Borah, J. C. (2024) · Fitoterapia · doi:10.1016/j.fitote.2023.105803 · Cited by 15

Therapeutic Role of Sirtuins Targeting Unfolded Protein Response, Coagulation, and Inflammation in Hypoxia-Induced Thrombosis

Sadia, K., Ashraf, M. Z., & Mishra, A. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.733453 · Cited by 17

Association of genetic variants in the Sirt1 and Nrf2 genes with the risk of metabolic syndrome in a Chinese Han population

Tao, T. T., Lin, X., Tang, S., Gui, W., Zhu, W., & Li, H. (2022) · BMC Endocrine Disorders · doi:10.1186/s12902-022-00965-0 · Cited by 14

Emerging cues mediating astroglia lineage restriction of progenitor cells in the injured/diseased adult CNS

Teng, F. Y. H., Hor, C. H. H., & Tang, B. L. (2009) · Differentiation · doi:10.1016/j.diff.2008.09.013 · Cited by 14

Metformin, metabolic stress, and mitochondria. Focus on “A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells”

Sugden, M. C., & Holness, M. J. (2012) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00090.2012 · Cited by 14

Obesity-induced upregulation of miR-361-5p promotes hepatosteatosis through targeting Sirt1

Zhang, Z., Liu, X., Xu, H., Feng, X., Lin, Y., Huang, Y., Peng, Y., & Gu, M. (2018) · Metabolism · doi:10.1016/j.metabol.2018.08.007 · Cited by 14

Sirtuin1 in vascular endothelial function, an overview

Kumar, J., & Kumar, S. (2021) · Epigenetics · doi:10.1080/15592294.2021.1975936 · Cited by 14

Is Fasting Good When One Is at Risk of Liver Cancer?

Minciună, I., van Kleef, L. A., Ştefănescu, H., & Procopeț, B. (2022) · Cancers · doi:10.3390/cancers14205084 · Cited by 13

PM2.5-induced premature senescence in HUVECs through the SIRT1/PGC-1α/SIRT3 pathway

Yan, Q., Zheng, R., Li, Y., Hu, J., Gong, M., Lin, M., Xu, X., Wu, J., & Sun, S. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.171177 · Cited by 13

DEHP regulates ferritinophagy to promote testicular ferroptosis via suppressing SIRT1/PGC-1α pathway

Zhu, Q., Zhai, J., Chen, Z., Guo, Z., Sun, X., Li, J., Wang, N., Yao, X., Zhang, C., Deng, H., et al. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.176497 · Cited by 13

Ergothioneine-rich Lentinula edodes mushroom extract restores mitochondrial functions in senescent HT22 cells

Apparoo, Y., Phan, C., Kuppusamy, U. R., & Chan, E. W. C. (2024) · Neuroscience · doi:10.1016/j.neuroscience.2024.11.082 · Cited by 13

Distinct and additive effects of sodium bicarbonate and continuous mild heat stress on fiber type shift via calcineurin/NFAT pathway in human skeletal myoblasts

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