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SR-BI-mediated High Density Lipoprotein (HDL) Endocytosis Leads to HDL Resecretion Facilitating Cholesterol Efflux
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SR-BI is endocytosed and localized in recycling endosomes.
“Several studies have shown that SR-BI is endocytosed (59,60) and localized in recycling endosomes (60).”
From The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance (2019) · cites this paper as [59]
The section on holo-HDL particle uptake reports internalization of SR-BI-GFP alongside HDL, supporting SR-BI endocytosis. The passage on the endosomal recycling compartment describes HDL particles being transported there, not localization of SR-BI itself; the copy does not establish that part of the claim. Page numbers are unavailable in our copy. (LLM, conf=0.86)
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Cited by
Sorted by citations
Adrenal cholesterol utilization
Kraemer, F. B. (2007) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.12.001 · Cited by 171
The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance
Wijers, M., Zanoni, P., Liv, N., Vos, D. Y., Jäckstein, M. Y., Smit, M., Wilbrink, S., Wolters, J. C., van der Veen, Y. T., Huijkman, N., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.126462 · Cited by 44
Metadata
- Authors
- Pagler, T. A., Rhode, S., Neuhofer, A., Laggner, H., Strobl, W., Hinterndorfer, C., Volf, I., Pavelka, M., Eckhardt, E. R. M., van der Westhuyzen, D. R., Schütz, G. J., & Stangl, H.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2006-04
- Volume
- 281
- Issue
- 16
- Pages
- 11193-11204
- ISSN
- 0021-9258
- Cited by
- 119
- References
- 0
- Language
- en
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