Evolutionarily Conserved Mammalian Adenine Nucleotide Translocase 4 Is Essential for Spermatogenesis

The mitochondrial permeability transition

Zoratti, M., & Szabó, I. (1995) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(95)00003-a · Cited by 2,395 · see citing works

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

Kokoszka, J. E., Waymire, K. G., Levy, S. E., Sligh, J. E., Cai, J., Jones, D. P., MacGregor, G. R., & Wallace, D. C. (2004) · Nature · doi:10.1038/nature02229 · Cited by 1,086 · see citing works

Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions

Van Goethem, G., Dermaut, B., Löfgren, A., Martin, J.-J., & Van Broeckhoven, C. (2001) · Nature Genetics · doi:10.1038/90034 · Cited by 841 · see citing works

Mili, a mammalian member ofpiwifamily gene, is essential for spermatogenesis

Kuramochi‐Miyagawa, S., Kimura, T., Ijiri, T. W., Isobe, T., Asada, N., Fujita, Y., Ikawa, M., Iwai, N., Okabe, M., Deng, W. W., et al. (2004) · Development · doi:10.1242/dev.00973 · Cited by 763 · see citing works

H2AX Is Required for Chromatin Remodeling and Inactivation of Sex Chromosomes in Male Mouse Meiosis

Fernández-Capetillo, Ó., Mahadevaiah, S. K., Celeste, A., Romanienko, P. J., Camerini‐Otero, R. D., Bonner, W. M., Manova, K., Burgoyne, P. S., & Nussenzweig, A. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00093-5 · Cited by 598 · see citing works

Oxidative Stress, Thiol Reagents, and Membrane Potential Modulate the Mitochondrial Permeability Transition by Affecting Nucleotide Binding to the Adenine Nucleotide Translocase

Halestrap, A. P., Woodfield, K.-Y., & Connern, C. P. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.6.3346 · Cited by 592 · see citing works

Sex Chromosome Specialization and Degeneration in Mammals

Graves, J. A. M. (2006) · Cell · doi:10.1016/j.cell.2006.02.024 · Cited by 591 · see citing works

A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator

Graham, B. H., Waymire, K. G., Cottrell, B. A., Trounce, I. A., MacGregor, G. R., & Wallace, D. C. (1997) · Nature Genetics · doi:10.1038/ng0797-226 · Cited by 556 · see citing works

Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene

McCarrey, J. R., & Thomas, K. (1987) · Nature · doi:10.1038/326501a0 · Cited by 484 · see citing works

Interactions of Cyclophilin with the Mitochondrial Inner Membrane and Regulation of the Permeability Transition Pore, a Cyclosporin A-sensitive Channel

Nicolli, A., Basso, E., Petronilli, V., Wenger, R. M., & Bernardi, P. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.4.2185 · Cited by 482 · see citing works

Extensive Gene Traffic on the Mammalian X Chromosome

Emerson, J. J., Kaessmann, H., Betrán, E., & Long, M. (2004) · Science · doi:10.1126/science.1090042 · Cited by 419 · see citing works

Postmeiotic Sex Chromatin in the Male Germline of Mice

Namekawa, S. H., Park, P. J., Zhang, L., Shima, J. E., McCarrey, J. R., Griswold, M. D., & Lee, J. T. (2006) · Current Biology · doi:10.1016/j.cub.2006.01.066 · Cited by 396 · see citing works

A coiled‐coil related protein specific for synapsed regions of meiotic prophase chromosomes.

Meuwissen, R. L. J., Offenberg, H. H., Dietrich, A. J. J., Riesewijk, A. M., IERSEL, M. V., & Heyting, C. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05616.x · Cited by 392 · see citing works

Differential expression of adenine nucleotide translocator isoforms in mammalian tissues and during muscle cell differentiation.

Stepien, G., Torroni, A., Chung, A. B., Hodge, J. A., & Wallace, D. C. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42082-0 · Cited by 325 · see citing works

Pachytene Asynapsis Drives Meiotic Sex Chromosome Inactivation and Leads to Substantial Postmeiotic Repression in Spermatids

Turner, J. M. A., Mahadevaiah, S. K., Ellis, P. J. I., Mitchell, M. J., & Burgoyne, P. S. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.02.009 · Cited by 278 · see citing works

Mitochondria-related male infertility

Nakada, K., Sato, A., Yoshida, K., Morita, T., Tanaka, H., Inoue, S., Yonekawa, H., & Hayashi, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604641103 · Cited by 266 · see citing works

A fourth ADP/ATP carrier isoform in man: identification, bacterial expression, functional characterization and tissue distribution

Dolce, V., Scarcia, P., Iacopetta, D., & Palmieri, F. (2004) · FEBS Letters · doi:10.1016/j.febslet.2004.12.034 · Cited by 222 · see citing works

A distinct cyclin A is expressed in germ cells in the mouse

Sweeney, C., Murphy, M. J., Kubelka, M., et al. (1996) · Development · doi:10.1242/dev.122.1.53 · Cited by 218 · see citing works

Increase in liver acetyl — Coenzyme a during ketosis

WIELAND, O. H., & Weiß, L. (1963) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(63)90534-5 · Cited by 214 · see citing works

The mitochondrial ADP/ATP carrier: Structural, physiological and pathological aspects

Fiore, C., Trézéguet, V., Le Saux, A., Roux, P., Schwimmer, C., Dianoux, A. C., Noel, F., Lauquin, G. J.-M., Brandolin, G., & Vignais, P. V. (1998) · Biochimie · doi:10.1016/s0300-9084(98)80020-5 · Cited by 209 · see citing works

Mitochondrial Deoxyribonucleic Acid 4977-bp Deletion is Associated with Diminished Fertility and Motility of Human Sperm1

Kao, S., Chao, H., & Wei, Y. (1995) · Biology of Reproduction · doi:10.1095/biolreprod52.4.729 · Cited by 197 · see citing works

Andrology: Mitochondrial disease and reduced sperm motility

Folgerø, T., Bertheussen, K., Lindal, S., et al. (1993) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a137950 · Cited by 197 · see citing works

Complete loss-of-function of the heart/muscle-specific adenine nucleotide translocator is associated with mitochondrial myopathy and cardiomyopathy

Palmieri, L., Alberio, S., Pisano, I., Lodi, T., Meznarič, M., Zidar, J., Santoro, A., Scarcia, P., Fontanesi, F., Lamantea, E., et al. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi341 · Cited by 186 · see citing works

Dynamic histone modifications mark sex chromosome inactivation and reactivation during mammalian spermatogenesis

Khalil, A. M., Boyar, F. Z., & Driscoll, D. J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406325101 · Cited by 181 · see citing works

Targeted disruption of p70 s6k defines its role in protein synthesis and rapamycin sensitivity

Kawasome, H., Papst, P. J., Webb, S., Keller, G. M., Johnson, G. L., Gelfand, E. W., & Terada, N. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.9.5033 · Cited by 179 · see citing works

Molecular weight and hydrodynamic parameters of the adenosine 5'-diphosphate-adenosine 5'-triphosphate carrier in Triton X-100

HACKENBERG, H., & Klingenberg, M. (1980) · Biochemistry · doi:10.1021/bi00544a024 · Cited by 178 · see citing works

The Mouse and Human Homologs of DMC1, the Yeast Meiosis-Specific Homologous Recombination Gene, Have a Common Unique form of Exon-Skipped Transcript in Meiosis

Habu, T., Taki, T., West, A., et al. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.3.470 · Cited by 173 · see citing works

Can mitochondrial DNA mutations cause sperm dysfunction?

Spiropoulos, J. (2002) · Molecular Human Reproduction · doi:10.1093/molehr/8.8.719 · Cited by 168 · see citing works

Human Fetal Mesenchymal Stem Cells as Vehicles for Gene Delivery

Chan, J. K. Y., O’Donoghue, K., de la Fuente, J., Roberts, I. A. G., Kumar, S., Morgan, J. E., & Fisk, N. M. (2005) · Stem Cells · doi:10.1634/stemcells.2004-0138 · Cited by 163 · see citing works

Differential transcription of Pgk genes during spermatogenesis in the mouse

McCarrey, J. R., Berg, W. M., Paragioudakis, S. J., et al. (1992) · Developmental Biology · doi:10.1016/0012-1606(92)90056-m · Cited by 154 · see citing works

X chromosomes, retrogenes and their role in male reproduction

Wang, P. J. (2004) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2004.01.007 · Cited by 128 · see citing works

A Mouse Homeo Box Gene Is Expressed in Spermatocytes and Embryos

Rubin, M. R., Toth, L. E., Patel, M. D., et al. (1986) · Science · doi:10.1126/science.3726554 · Cited by 122 · see citing works

The adenine nucleotide translocator in apoptosis

Belzacq, A.-S., Vieira, H. L. A., Kroemer, G., & Brenner, C. (2002) · Biochimie · doi:10.1016/s0300-9084(02)01366-4 · Cited by 117 · see citing works

Compartmentalization of a unique ADP/ATP carrier protein SFEC (Sperm Flagellar Energy Carrier, AAC4) with glycolytic enzymes in the fibrous sheath of the human sperm flagellar principal piece

Kim, Y.-H., Haidl, G., Schäfer, M., Egner, U., Mandal, A., & Herr, J. C. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.10.004 · Cited by 106 · see citing works

Oligoasthenospermia associated with multiple mitochondrial DNA rearrangements

Lestienne, P. P. (1997) · Molecular Human Reproduction · doi:10.1093/molehr/3.9.811 · Cited by 106 · see citing works

An X-to-autosome retrogene is required for spermatogenesis in mice

Bradley, J., Baltus, A. E., Skaletsky, H., Royce-Tolland, M., Dewar, K., & Page, D. C. (2004) · Nature Genetics · doi:10.1038/ng1390 · Cited by 105 · see citing works

Expression and sequence analysis of the mouse adenine nucleotide translocase 1 and 2 genes

Levy, S., Chen, Y., Graham, B. H., & Wallace, D. C. (2000) · Gene · doi:10.1016/s0378-1119(00)00252-3 · Cited by 93 · see citing works

Structure-function studies of adenine nucleotide transport in mitochondria. II. Biochemical analysis of distinct AAC1 and AAC2 proteins in yeast.

Gawaz, M., Douglas, M. G., & Klingenberg, M. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)77287-6 · Cited by 93 · see citing works

DNA Methylation Is Required for Silencing of <i>Ant4</i> , an Adenine Nucleotide Translocase Selectively Expressed in Mouse Embryonic Stem Cells and Germ Cells

Rodić, N., Oka, M., Hamazaki, T., Murawski, M. R., Jorgensen, M., Maatouk, D. M., Resnick, J. L., Li, E., & Terada, N. (2005) · STEM CELLS · doi:10.1634/stemcells.2005-0119 · Cited by 89 · see citing works

Stage‐specific and tissue‐specific expression characteristics of differentially expressed genes during mouse spermatogenesis

Guo, R., Yu, Z., Guan, J., et al. (2004) · Molecular Reproduction and Development · doi:10.1002/mrd.20026 · Cited by 72 · see citing works

Complex Events in the Evolution of the Human Pseudoautosomal Region 2 (PAR2)Preprint

Charchar, F. J., Svartman, M., El‐Mogharbel, N., et al. (2003) · Genome Research · doi:10.1101/gr.390503 · Cited by 71 · see citing works

Murine A-myb: evidence for differential splicing and tissue-specific expression.

Mettus, R. V., Litvin, J., Wali, A., et al. (1994) · PubMed · Cited by 70 · see citing works

Quantitation of mRNAs during mouse spermatogenesis: protamine-like histone and phosphoglycerate kinase-2 mRNAs increase after meiosis.

Erickson, R. P., Kramer, J. M., Rittenhouse, J., et al. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.10.6086 · Cited by 58 · see citing works

The multiple ADP/ATP translocase genes are differentially expressed during human muscle development.

Lunardi, J., Hurko, O., Engel, W. K., et al. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)49526-4 · Cited by 52 · see citing works

Defect in germ cells, not in supporting cells, is the cause of male infertility in the jsd mutant mouse: proliferation of spermatogonial stem cells without differentiation

Ohta, H., Yomogida, K., Tadokoro, Y., et al. (2001) · International Journal of Andrology · doi:10.1046/j.1365-2605.2001.00257.x · Cited by 52 · see citing works

Male infertility and mitochondrial DNA

Carra, E., Sangiorgi, D., Gattuccio, F., et al. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.07.112 · Cited by 46 · see citing works

Expression of Deoxyribonucleic Acid Repair Enzymes During Spermatogenesis in Mice1

Richardson, L. L., Pedigo, C., & Handel, M. A. (2000) · Biology of Reproduction · doi:10.1095/biolreprod62.3.789 · Cited by 45 · see citing works

Epigenetic Regulation of Testis‐Specific Gene Expression

McCarrey, J. R., Geyer, C. B., & Yoshioka, H. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1336.025 · Cited by 32 · see citing works

CSF2RA, ANT3, and STS are autosomal in marsupials: implications for the origin of the pseudoautosomal region of mammalian sex chromosomes

Toder, R., & Graves, J. A. M. (1998) · Mammalian Genome · doi:10.1007/s003359900772 · Cited by 27 · see citing works

Molecular characterization of the porcine testis-specificphosphoglycerate kinase 2 (PGK2) gene and its association with male fertility

Chen, K., Knörr, C., Moser, G., et al. (2004) · Mammalian Genome · doi:10.1007/s00335-004-2405-1 · Cited by 22 · see citing works

The evolution of the adenine nucleotide translocase family

Santamaría, M., Lanave, C., & Saccone, C. (2004) · Gene · doi:10.1016/j.gene.2004.02.013 · Cited by 20 · see citing works

Mutation D104G in ANT1 gene: Complementation study in Saccharomyces cerevisiae as a model system

Lodi, T., Bove, C. G., Fontanesi, F., et al. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.01.034 · Cited by 17 · see citing works

Genetic Mapping of the Adenine Nucleotide Translocase-2 Gene (Ant2) to the Mouse Proximal X Chromosome

Ellison, J. W., SALIDO, E. C., & Shapiro, L. J. (1996) · Genomics · doi:10.1006/geno.1996.0478 · Cited by 15 · see citing works

Synopsis: 2005 Annual Meeting of the American Society of Andrology

Bailey, J. L., Evans, J. P., Hardy, M., et al. (2005) · Journal of Andrology · doi:10.2164/jandrol.05125 · Cited by 1 · see citing works

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death &amp; Differentiation · doi:10.1038/s41418-017-0012-4 · Cited by 6,680 · see citing works

A 20/20 view of ANT function in mitochondrial biology and necrotic cell death

Bround, M. J., Bers, D. M., & Molkentin, J. D. (2020) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2020.05.012 · Cited by 83 · see citing works

Hormonal induction of all stages of spermatogenesis in germ‐somatic cell coculture from immature Japanese eel testis

Miura, C., Miura, T., Yamashita, M., et al. (1996) · Development Growth & Differentiation · doi:10.1046/j.1440-169x.1996.t01-2-00004.x · Cited by 78 · see citing works

Comparison of somatic and germ cell models for cytogenetic screening

Holden, H. E. (1982) · Journal of Applied Toxicology · doi:10.1002/jat.2550020405 · Cited by 59 · see citing works

Germ cell fate and seminiferous tubule development in bovine testis xenografts

Rathi, R., Honaramooz, A., Zeng, W., et al. (2005) · Reproduction · doi:10.1530/rep.1.00912 · Cited by 80 · see citing works

Approaches for identifying germ cell mutagens: Report of the 2013 IWGT workshop on germ cell assays☆

Yauk, C. L., Aardema, M. J., van Benthem, J., Bishop, J. B., Dearfield, K. L., DeMarini, D. M., Dubrova, Y. E., Honma, M., Lupski, J. R., Marchetti, F., et al. (2015) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2015.01.008 · Cited by 112 · see citing works

Fas expression correlates with human germ cell degeneration in meiotic and post-meiotic arrest of spermatogenesis

Francavilla, S. (2002) · Molecular Human Reproduction · doi:10.1093/molehr/8.3.213 · Cited by 67 · see citing works