Dietary α-linolenic acid and health-related outcomes: a metabolic perspective

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1. Effects of Dietary Lipid Composition and Fatty Acid Desaturase 2 Expression in Broodstock Gilthead Sea Bream on Lipid Metabolism-Related Genes and Methylation of the fads2 Gene Promoter in Their Offspring
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2. Effect of the combined supplementation of diets with increasing levels of fish and linseed oils on yolk fat composition and sensorial quality of eggs in laying hens
   Paloma Garcia-Rebollar, Pilar Cachaldora, C. Alvarez, Carlos De Blas, Jesús Méndez · 2007 · Animal Feed Science and Technology
3. Is fatty acid composition of human bone marrow significant to bone health?
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4. Dietary PUFA and flavonoids as deterrents for environmental pollutants
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5. Postgraduate Symposium Long-chainn-3 PUFA: intakes in the UK and the potential of a chicken meat prototype to increase them
   Rachael A. Gibbs, C. Rymer, David Ian Givens · 2009 · Proceedings of The Nutrition Society
6. Rapid quantitation of fish oil fatty acids and their ethyl esters by FT‐NIR models
   Hormoz Azizian, John K. G. Kramer, Shannon Ehler, Jonathan M. Curtis · 2010 · European Journal of Lipid Science and Technology
7. Maternal intake of flaxseed-based diet (Linum usitatissimum) on hippocampus fatty acid profile: Implications for growth, locomotor activity and spatial memory
   Flávia Spreafico Fernandes, Amanda Santos de Souza, Maria das Graças Tavares do Carmo, Gilson Teles Boaventura · 2011 · Nutrition
8. EPA+DHA, but not ALA, Improved Lipids and Inflammation Status in Hypercholesterolemic Adults: A Randomized, Double‐Blind, Placebo‐Controlled Trial
   Quan Zhou, Zheqing Zhang, Ping Wang, Bo Zhang, Chaogang Chen, Cai‐Xia Zhang, Yixiang Su · 2019 · Molecular Nutrition & Food Research
9. Benefits of blended oil consumption over other sources of lipids on the cardiovascular system in obese rats
   Angelo Uriho, Shaojun Yang, Xue Tang, Chang-Shu Liu, Sai Wang, Cong Yang, Junwei Zhang, Peng Zhou · 2019 · Food & Function
10. Long-chain polyunsaturated fatty acids and inflammation
    Philip C. Calder · 2006 · Scandinavian Journal of Food & Nutrition
11. Influence of duration of supplementation with ruminally protected linseed oil on the fatty acid composition of feedlot lambs
    Soressa M. Kitessa, Andrew J. Williams, S.K. Gulati, Vivian Boghossian, John Reynolds, Kelly L. Pearce · 2009 · Animal Feed Science and Technology
12. Genetically modified plants are an alternative to oily fish for providing n‐3 polyunsaturated fatty acids in the human diet: A summary of the findings of a Biotechnology and Biological Sciences Research Council funded project
    Annette L. West, Elizabeth A. Miles, Karen A. Lillycrop, Johnathan A. Napier, Philip C. Calder, Graham C. Burdge · 2020 · Nutrition Bulletin
13. N-3 Polyunsaturated Fatty Acids and Gut Microbiota
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14. A comparison of heart rate variability,n-3 PUFA status and lipid mediator profile in age- and BMI-matched middle-aged vegans and omnivores
    Ana M. Pinto, T. A. B. Sanders, Alexandra C. Kendall, Anna Nicolaou, Robert Gray, Haya Al Khatib, Wendy Louise Hall · 2017 · British Journal Of Nutrition
15. Perilla Seed Oil Enhances Cognitive Function and Mental Health in Healthy Elderly Japanese Individuals by Enhancing the Biological Antioxidant Potential
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16. Concentration of selected fatty acids, fat-soluble vitamins and β-carotene in late lactation mares' milk
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17. Site Distribution at the Edge of the Palaeolithic World: A Nutritional Niche Approach
    Antony Gavin Brown, Laura Basell, Sian M. Robinson, Graham C. Burdge · 2013 · PLoS ONE
18. Effects of a hypoenergetic diet rich in α-linolenic acid on fatty acid composition of serum phospholipids in overweight and obese patients with metabolic syndrome
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19. The PREDIMED study
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20. Is essential fatty acid interconversion an important source of PUFA in humans?
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21. Male-Specific Cardiac Dysfunction in CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2)-Deficient Mice
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22. Extraction Process, Identification of Fatty Acids, Tocopherols, Sterols and Phenolic Constituents, and Antioxidant Evaluation of Seed Oils from Five Fabaceae Species
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23. Evaluation of Plant Protein Hydrolysates as Natural Antioxidants in Fish Oil-In-Water Emulsions
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24. Changes in plasma and erythrocyte omega-6 and omega-3 fatty acids in response to intravenous supply of omega-3 fatty acids in patients with hepatic colorectal metastases
    Omer Al‐Taan, James Andrew Stephenson, Laura Spencer, Cristina A. Pollard, Annette L. West, Philip C. Calder, Matthew S. Metcalfe, Ashley Robert Dennison · 2013 · Lipids in Health and Disease
25. Oxidative Stress in Chronic Liver Disease and Portal Hypertension: Potential of DHA as Nutraceutical
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26. Harmful, harmless or helpful? The n-6 fatty acid debate goes on
    Philip C. Calder, Richard Joseph Deckelbaum · 2011 · Current Opinion in Clinical Nutrition & Metabolic Care
27. Effect of lipid type on growth performance, meat quality and the content of long chain n−3 fatty acids in pork meat
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28. Omega-3 fatty acids: time to get the messages right!
    Philip C. Calder, Richard Joseph Deckelbaum · 2008 · Current Opinion in Clinical Nutrition & Metabolic Care
29. PHARMACOLOGICAL PROPERTIES OF SALVIA HISPANICA (CHIA) SEEDS: A REVIEW
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30. Impact of a cafeteria diet and daily physical training on the rat serum metabolome
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31. Effect of Long-Term Combined Oral Contraceptive Pill Use on Endometrial Thickness
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32. Effects of Omega-3 Long Chain Polyunsaturated Fatty Acid Supplementation on Equine Synovial Fluid Fatty Acid Composition and Prostaglandin E2
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33. Plasma eicosapentaenoic acid is negatively associated with all-cause mortality among men and women in a population-based prospective study
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34. Comparison of fatty acids in beef tissues from conventional, organic and natural feeding systems in western Canada
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35. Effects of extruded flaxseed on layer performance, nutrient retention and yolk fatty acid composition
    Shuai Huang, Bushansingh Baurhoo, Arif F Mustafa · 2018 · British Poultry Science
36. Effects of α-linolenic acid supplementation in perilla oil on collagen-epinephrine closure time, activated partial thromboplastin time and Lp-PLA 2 activity in non-diabetic and hypercholesterolaemic subjects
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37. Fatty acid elongase7 is regulated via SP1 and is involved in lipid accumulation in bovine mammary epithelial cells
    Si Chen, Zhigang Hu, Hua He, Xiaolin Liu · 2017 · Journal of Cellular Physiology
38. Precision Nutrition and Cardiovascular Disease Risk Reduction: the Promise of High-Density Lipoproteins
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39. Membrane Fatty Acids, Oxidative Burst and Phagocytosis after Enrichment of P388D1 Monocyte/Macrophages with Essential 18-Carbon Fatty Acids
    Herbert Fuhrmann, Elizabeth A. Miles, Annette L. West, Philip C. Calder · 2007 · Annals of Nutrition and Metabolism
40. Validation of a Dietary Questionnaire to Screen Omega-3 Fatty Acids Levels in Healthy Adults
    Wan Shen, Anne M. Weaver, Claudia Salazar, James M. Samet, David Díaz-Sánchez, Haiyan Tong · 2019 · Nutrients
41. Comprehensive Identification of Principal Lipid Classes and Tocochromanols in Silkworm (Antheraea pernyi and Bombyx mori) Pupae Oils
    Weifei Wang, Long Xu, Yuxiao Zou, Daorui Pang, Wei Shi, Lixia Mu, Erna Li, Dongming Lan, Yonghua Wang, Sentai Liao · 2019 · European Journal of Lipid Science and Technology
42. Altered oxylipin levels in human vitreous indicate imbalance in pro-/anti-inflammatory homeostasis in proliferative diabetic retinopathy
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43. Update on the management of severe hypertriglyceridemia – focus on free fatty acid forms of omega-3
    Alberico Luigi Catapano, Angela Pirillo · 2015 · Drug Design Development and Therapy
44. Evidence of inadequate docosahexaenoic acid status in Brazilian pregnant and lactating women
    Alexandre Guedes Torres, Nádia M.F. Trugo · 2009 · Revista de Saúde Pública
45. Lowering the linoleic acid to alpha-linoleic acid ratio decreases the production of inflammatory mediators by cultured human endothelial cells
    Christian Sørensen Bork, Ella J. Baker, Søren Lundbye‐Christensen, Elizabeth A. Miles, Philip C. Calder · 2018 · Prostaglandins Leukotrienes and Essential Fatty Acids
46. Effects of the flavonol quercetin andα-linolenic acid onn-3 PUFA status in metabolically healthy men and women: a randomised, double-blinded, placebo-controlled, crossover trial
    Constanze Burak, Siegfried Wolffram, Berndt Zur, Peter Langguth, Rolf Fimmers, Birgit Alteheld, Peter Stehle, Sarah Egert · 2017 · British Journal Of Nutrition
47. Marine n-3 Fatty Acids and the Risk of Peripheral Arterial Disease
    Anne N. Lasota, Marie-Louise Moes Grønholdt, Christian Sørensen Bork, Søren Lundbye‐Christensen, Kim Overvad, Erik Berg Schmidt · 2018 · Journal of the American College of Cardiology
48. A systematic review and meta-analysis of clinical trials investigating the effects of flaxseed supplementation on plasma C-reactive protein concentrations
    Sorin Ursoniu, Amirhossein Sahebkar, Maria-Corina Șerban, Iulia Pînzaru, Cristina Adriana Dehelean, Lavinia Noveanu, Jacek Rysz, Maciej Banach · 2019 · Archives of Medical Science
49. Different Dietary N-3 Polyunsaturated Fatty Acid Formulations Distinctively Modify Tissue Fatty Acid and N-Acylethanolamine Profiles
    Elisabetta Murru, Paula A. Lopes, Gianfranca Carta, Claudia Manca, Armita Abolghasemi, José Luis Guil‐Guerrero, José A. M. Prates, Sebastiano Banni · 2021 · Nutrients
50. Nutritional benefits of omega-3 fatty acids
    Philip C. Calder · 2013 · Elsevier eBooks
51. Neurotrophic Factors and Maternal Nutrition During Pregnancy
    Madhavi V. Dhobale · 2016 · Vitamins and hormones
52. Enriching milk fat with n−3 polyunsaturated fatty acids by supplementing grazing dairy cows with ruminally protected Echium oil
    Soressa M. Kitessa, Paul Young · 2011 · Animal Feed Science and Technology
53. Docosahexaenoic Acid-Enriched Phosphatidylcholine Exerted Superior Effects to Triglyceride in Ameliorating Obesity-Induced Osteoporosis through Up-Regulating the Wnt/β-Catenin Pathway
    Hao Yue, Yuying Bo, Yingying Tian, Lei Mao, Changhu Xue, Ping Dong, Jingfeng Wang · 2022 · Journal of Agricultural and Food Chemistry
54. Dietary fatty acid profile: effects on caecal fermentation and performance of young and fattening rabbits
    Cristina Casado, V.J. Moya, Juan José Pascual, E. Blas, Concha Cervera · 2013 · World Rabbit Science
55. Is there A Role for Alpha-Linolenic Acid in the Fetal Programming of Health?
    Alicia I. Leikin-Frenkel · 2016 · Journal of Clinical Medicine
56. Eicosapentaenoic acid and/or aspirin for preventing colorectal adenomas during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme: the seAFOod RCT
    Mark A. Hull, Kirsty Sprange, Trish Hepburn, Wei Tan, Aisha Shafayat, Colin John Rees, Gayle M. Clifford, Richard F. Logan, Paul M. Loadman, Elizabeth A. Williams et al. · 2019 · Efficacy and Mechanism Evaluation
57. Postprandial lipid responses to an alpha-linolenic acid-rich oil, olive oil and butter in women: A randomized crossover trial
    Julia Svensson, Anna Rosenquist, Lena Ohlsson · 2011 · Lipids in Health and Disease
58. Effect of dietary EPA and DHA on murine blood and liver fatty acid profile and liver oxylipin pattern depending on high and low dietary n6-PUFA
    Laura Kutzner, Carsten Esselun, Nicole Franke, Kirsten Schoenfeld, Gunter Peter Eckert, Nils Helge Schebb · 2020 · Food & Function
59. Association of serum eicosapentaenoic acid to arachidonic acid ratio with microalbuminuria in a population of community-dwelling Japanese
    Ako Fukami, Hisashi Adachi, Yuji Hirai, Mika Enomoto, Maki Otsuka, Eita Kumagai, Sachiko Nakamura, Ayako Yoshimura, Aya Obuchi, Yume Nohara et al. · 2015 · Atherosclerosis
60. Enrichment of RAW264.7 macrophages with essential 18-carbon fatty acids affects both respiratory burst and production of immune modulating cytokines
    Bernd Walloschke, Herbert Fuhrmann, Julia E. Schumann · 2009 · The Journal of Nutritional Biochemistry
61. Regulatory Mechanisms of EPA and DHA Proportions in a PUFA-Producing Microalga, Schizochytrium sp. ATCC 20888: From the Biosynthesis and Storage Distribution Aspects
    Yaqi Xu, Zhao Zhang, Yanqing Bian, Yuanhao Wang, Ziliang Deng, Rui Luo, Weijia Li, Jingyi Yan, Baohua Zhao, Daye Sun · 2025 · Journal of Agricultural and Food Chemistry
62. Effect of Dietary Combination of Methionine and Fish Oil on Cellular Immunity and Plasma Fatty Acids in Infectious Bursal Disease Challenged Chickens
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63. Effects of feeding camelina cake to weaned pigs on safety, growth performance, and fatty acid composition of pork1
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64. Omega-3 Polyunsaturated Fatty Acid Metabolism in Vegetarians
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65. Sex- and Age-Related Metabolic Characteristics of Serum Free Fatty Acids in Healthy Chinese Adults
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66. Omega-3 fatty acid intake and decreased risk of skin cancer in organ transplant recipients
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67. Effects of plant oils with different fatty acid composition on cardiovascular risk factors in moderately hypercholesteremic Chinese adults: a randomized, double-blinded, parallel-designed trial
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68. Vitamin D and Omega-3 (Fatty Acid) Supplementation in Pregnancy for the Primary Prevention of Food Allergy in Children-Literature Review
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69. Chronic dietary intake of α-linolenic acid does not replicate the effects of DHA on passive properties of entorhinal cortex neurons
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70. The role of dietary polyunsaturated fatty acids in inflammation
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71. Overcoming the Bitter Taste of Oils Enriched in Fatty Acids to Obtain Their Effects on the Heart in Health and Disease
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72. Association of dietary n-3 polyunsaturated fatty acids intake with depressive symptoms in midlife women
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73. Effect of sex and dietary fat intake on the fatty acid composition of phospholipids and triacylglycerol in rat heart
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74. Dietary (n-6 : n-3) Fatty Acids Alter Plasma and Tissue Fatty Acid Composition in Pregnant Sprague Dawley Rats
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75. Spirulina supplementation and its effects on inflammation and oxidative stress: A systematic review and Meta-analysis on randomized clinical trials
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76. FADS2 genotype influences whole-body resting fat oxidation in young adult men
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77. Flavonoids as putative modulators of Δ4‐, Δ5‐, and Δ6‐desaturases: Studies in cultured hepatocytes, myocytes, and adipocytes
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78. The effect of altering the 20:5n-3 and 22:6n-3 content of a meal on the postprandial incorporation of n-3 polyunsaturated fatty acids into plasma triacylglycerol and non-esterified fatty acids in humans
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79. n−3 fatty acids: functional differences between food intake, oral supplementation and drug treatments
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80. In Vitro and In Vivo Anti-Inflammatory Effects of Cannabis sativa Stem Extract
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81. Different dietary omega-3 sources during pregnancy and DHA in the developing rat brain
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82. Effects of duodenal infusion of free α-linolenic acid on the plasma and milk proteome of lactating dairy cows
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83. miR-26a mediates LC-PUFA biosynthesis by targeting the Lxrα–Srebp1 pathway in the marine teleost Siganus canaliculatus
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84. Fatty Acid Profiles of Mediterranean Wild Edible Plants
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85. Lack of evidence for Omega-3 fatty acid supplementation in enhancing lean mass, muscle strength, and physical function in healthy adults and clinical populations: an overview of reviews.
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86. An Optimized Ex Vivo n –3 PUFA Supplementation Strategy for Primary Human Macrophages Shows That DHA Suppresses Prostaglandin E2 Formation
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90. Polyunsaturated fatty acid intakes and α-linolenic acid metabolism
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91. Dietary Antioxidant Properties of Vegetable Oils and Nuts – The Race Against Cardiovascular Disease Progression
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92. Alpha-Linolenic acid: A Pharmacologically Active Ingredient from Nature
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93. Effect of essential fatty acid blend on circadian variations of ambulatory blood pressure in patients with essential hypertension and coronary artery disease risk markers
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94. Postprandial lipemic response to alpha‐linolenic acid rich oil, butter, and olive oil
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95. Sex specific differences in hepatic and plasma lipid profiles in healthy cats pre and post spaying and neutering: relationship with feline hepatic lipidosis
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96. Long chain fatty acids metabolism and cardiovascular risk factors in youth with type 1 diabetes
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97. In Vivo Antitumoral Effects of Linseed Oil and Its Combination With Doxorubicin
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98. Erythrocyte membrane and plasma non-esterified n-3 and n-6 polyunsaturated fatty acids of pregnant and non-pregnant Brazilian adolescents
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99. Formulation and Antimicrobial Activity on Escherichia coli of Nanoemulsion Coated with Whey Protein Isolate
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100. Populational segregation of Echium plantagineum L. based on seed oil fatty acid ratios as chemotaxonomical marker sets
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