The DOI matches its Crossref record.
Effects of basic fibroblast growth factor (bFGF) on early stages of tendon healing: A rat patellar tendon model
Open accessAbstract
We studied the effects of basic fibroblast growth factor (bFGF) on cell proliferation, type III collagen expression, ultimate stress and the pyridinoline content in the early stages of healing in rat patellar tendon. 96 male Sprague Dawley rats were injected with increasing doses of basic fibroblast growth factor (bFGF) at 3 days after a "window defect" was induced in the mid-part of the patellar tendon. They were killed at 7 and 14 days after the injury. A dose-dependent increase in the number of proliferating cells and the level of expression of type III collagen was demonstrated at only 7 days post-injury. On the other hand, we found no effects of bFGF on ultimate stress and the pyridinoline content of healing tendons. Only time significantly affected both strength-associated parameters. We showed that in vivo supplementation with bFGF affected the initial events of healing such as cell proliferation and type III collagen expression.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Pathogenesis of tendinopathies: inflammation or degeneration?
Abate, M., Gravare-Silbernagel, K., Siljeholm, C., Di Iorio, A., De Amicis, D., Salini, V., Werner, S., & Paganelli, R. (2009) · Arthritis Research & Therapy · doi:10.1186/ar2723 · Cited by 571
Kular, J. K., Basu, S., & Sharma, R. I. (2014) · Journal of Tissue Engineering · doi:10.1177/2041731414557112 · Cited by 559
Tendon and ligament regeneration and repair: Clinical relevance and developmental paradigm
Yang, G., Rothrauff, B. B., & Tuan, R. S. (2013) · Birth Defects Research Part C: Embryo Today: Reviews · doi:10.1002/bdrc.21041 · Cited by 469
Sahoo, S., Toh, S. L., & Goh, J. C. H. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.01.004 · Cited by 329
The Influence of Platelet-Rich Plasma on Angiogenesis During the Early Phase of Tendon Healing
Lyras, D. N., Kazakos, K., Verettas, D., Polychronidis, A., Tryfonidis, M., Botaitis, S., Agrogiannis, G., Simopoulos, C., Kokka, A., & Patsouris, E. (2009) · Foot & Ankle International · doi:10.3113/fai.2009.1101 · Cited by 147
Metadata
- Authors
- Chan, B. P., Fu, S.-C., Qin, L., Lee, K.-M., Rolf, C. G., & Chan, K.-M.
- Venue
- Acta Orthopaedica Scandinavica
- Published
- 2000-01
- Volume
- 71
- Issue
- 5
- Pages
- 513-518
- ISSN
- 0001-6470 (ISSN-L)
- OpenAlex
- W2029935659
- Cited by
- 218
- References
- 0
- FWCI
- 3.55
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Effects of basic fibroblast growth factor (bFGF) on early stages of tendon healing: A rat patellar tendon model. https://app.cochat.ai/papers/10.1080/000164700317381234
- The paper
- Chan, B. P., Fu, S.-C., Qin, L., Lee, K.-M., Rolf, C. G., & Chan, K.-M. (2000). Effects of basic fibroblast growth factor (bFGF) on early stages of tendon healing: A rat patellar tendon model. Acta Orthopaedica Scandinavica. https://doi.org/10.1080/000164700317381234
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
