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Cited by 406

The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.

A review of sleep disorders and melatonin

Open access
Xie, Zizhen, Chen, Fei, Li, William A., Geng, Xiaokun, Li, Changhong, Meng, Xiaomei, Feng, Yan, Liu, Wei, Yu, Fengchun·2017·Neurological Research

Abstract

Sleep disorders are a group of conditions that affect the ability to sleep well on a regular basis and cause significant impairments in social and occupational functions. Although currently approved medications are efficacious, they are far from satisfactory. Benzodiazepines, antidepressants, antihistamines and anxiolytics have the potential for dependence and addiction. Moreover, some of these medications can gradually impair cognition. Melatonin (N-acetyl-5-methoxytryptamine) is an endogenous hormone produced by the pineal gland and released exclusively at night. Exogenous melatonin supplementation is well tolerated and has no obvious short- or long-term adverse effects. Melatonin has been shown to synchronize the circadian rhythms, and improve the onset, duration and quality of sleep. It is centrally involved in anti-oxidation, circadian rhythmicity maintenance, sleep regulation and neuronal survival. This narrative review aims to provide a comprehensive overview of various therapeutic functions of melatonin in insomnia, sleep-related breathing disorders, hypersomnolence, circadian rhythm sleep-wake disorders and parasomnias. Melatonin offers an alternative treatment to the currently available pharmaceutical therapies for sleep disorders with significantly less side effects.

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Metadata

Authors
Xie, Z., Chen, F., Li, W. A., Geng, X., Li, C., Meng, X., Feng, Y., Liu, W., & Yu, F.
Venue
Neurological Research
Published
2017-05-01
Volume
39
Issue
6
Pages
559-565
ISSN
  • 0161-6412 (ISSN-L)
  • 1743-1328
OpenAlex
W2610909132
Cited by
406
References
52
FWCI
11.86
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: A review of sleep disorders and melatonin. https://app.cochat.ai/papers/10.1080/01616412.2017.1315864
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Xie, Z., Chen, F., Li, W. A., Geng, X., Li, C., Meng, X., Feng, Y., Liu, W., & Yu, F. (2017). A review of sleep disorders and melatonin. Neurological Research. https://doi.org/10.1080/01616412.2017.1315864

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